New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on: April 23,2024

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on:April 23,2024

Elegant antibody nanoparticles override immunological tolerance of tumors

by Chinese Academy of SciencesSchematic illustration of the engineered antibody nanoparticle for robust cancer immunotherapy. Credit: WANG DanggeImmune checkpoint blockade (ICB) therapy using the

Updated on: May 09,2024

Elegant antibody nanoparticles override immunological tolerance of tumors

by Chinese Academy of SciencesSchematic illustration of the engineered antibody nanoparticle for robust cancer immunotherapy. Credit: WANG DanggeImmune checkpoint blockade (ICB) therapy using the

Updated on:May 09,2024

Breast cancer researchers find bacteria imbalance link

by Cleveland ClinicCharis Eng, M.D., Ph.D., chair of the Cleveland Clinic's Genomic Medicine Institute. Credit: Cleveland ClinicResearchers in the United States have uncovered differences in

Updated on: June 15,2024

Breast cancer researchers find bacteria imbalance link

by Cleveland ClinicCharis Eng, M.D., Ph.D., chair of the Cleveland Clinic's Genomic Medicine Institute. Credit: Cleveland ClinicResearchers in the United States have uncovered differences in

Updated on:June 15,2024

Paper filter helps make new cancer drug 1000 times cheaper

by Eindhoven University of TechnologyLech-Gustav Milroy demonstrates the simple separation technique that took the place of the very expensive HPLC. In the background you can see HPLC equipment.

Updated on: April 10,2024

Paper filter helps make new cancer drug 1000 times cheaper

by Eindhoven University of TechnologyLech-Gustav Milroy demonstrates the simple separation technique that took the place of the very expensive HPLC. In the background you can see HPLC equipment.

Updated on:April 10,2024

Aspirin could play valuable role as additional treatment for cancer

by Cardiff UniversityCoated aspirin tablets. Image: Wikimedia Commons.Regular use of aspirin could help in the treatment of some cancers, finds a new review of 71 medical studies.Thesystema

Updated on: March 01,2024

Aspirin could play valuable role as additional treatment for cancer

by Cardiff UniversityCoated aspirin tablets. Image: Wikimedia Commons.Regular use of aspirin could help in the treatment of some cancers, finds a new review of 71 medical studies.Thesystema

Updated on:March 01,2024

Novel pretargeted radionuclide therapy for HER2-expressing cancers shows promise

by Society of Nuclear Medicine and Molecular ImagingTransversal (A), coronal (B), sagittal (C) nanoSPECT/CT images and maximum intensity projection (D) obtained 30 h after injection of pretargeted&nbs

Updated on: March 06,2024

Novel pretargeted radionuclide therapy for HER2-expressing cancers shows promise

by Society of Nuclear Medicine and Molecular ImagingTransversal (A), coronal (B), sagittal (C) nanoSPECT/CT images and maximum intensity projection (D) obtained 30 h after injection of pretargeted&nbs

Updated on:March 06,2024

Scientists develop a new model for glioblastoma using gene-edited organoids

by Salk InstituteOrganoids reveal how a deadly brain cancer grows. From left to right, tumor cells labeled with red fluorescent marker tdTomato spread in a cerebral organoid over a time period of

Updated on: March 01,2024

Scientists develop a new model for glioblastoma using gene-edited organoids

by Salk InstituteOrganoids reveal how a deadly brain cancer grows. From left to right, tumor cells labeled with red fluorescent marker tdTomato spread in a cerebral organoid over a time period of

Updated on:March 01,2024

Health insurance premiums dropped? Not so fast

by E.J. Antoni, The Heritage FoundationCredit: Pixabay/CC0 Public DomainThe latest Consumer Price Index report showed inflation slowing in October, due in part to a supposed 34% drop in the cost of he

Updated on: May 17,2024

Health insurance premiums dropped? Not so fast

by E.J. Antoni, The Heritage FoundationCredit: Pixabay/CC0 Public DomainThe latest Consumer Price Index report showed inflation slowing in October, due in part to a supposed 34% drop in the cost of he

Updated on:May 17,2024

Vaccine boosts response of engineered T cells, may help eradicate solid tumors

by Massachusetts Institute of TechnologyCredit: CC0 Public DomainEngineering T cells to destroy cancer cells has shown success in treating some types of cancer, such as leukemia and lymphoma. How

Updated on: January 30,2024

Vaccine boosts response of engineered T cells, may help eradicate solid tumors

by Massachusetts Institute of TechnologyCredit: CC0 Public DomainEngineering T cells to destroy cancer cells has shown success in treating some types of cancer, such as leukemia and lymphoma. How

Updated on:January 30,2024

Second primary malignancies represent small proportion of adverse events after CAR T-cell therapy

by Elana GotkineSecond primary malignancies (SPMs) represent a small proportion of adverse events (AEs) reported by patients receiving chimeric antigen receptor T-cell (CAR T-cell) therapy, according

Updated on: March 30,2024

Second primary malignancies represent small proportion of adverse events after CAR T-cell therapy

by Elana GotkineSecond primary malignancies (SPMs) represent a small proportion of adverse events (AEs) reported by patients receiving chimeric antigen receptor T-cell (CAR T-cell) therapy, according

Updated on:March 30,2024

South Florida girl in need of rare blood to fight cancer

Credit: CC0 Public DomainA worldwide search is on to find blood donors with a rare genetic variation to help save a 2-year-old South Florida girl battling cancer.Zainab Mughal has neuroblastoma and ne

Updated on: March 12,2024

South Florida girl in need of rare blood to fight cancer

Credit: CC0 Public DomainA worldwide search is on to find blood donors with a rare genetic variation to help save a 2-year-old South Florida girl battling cancer.Zainab Mughal has neuroblastoma and ne

Updated on:March 12,2024

Deep learning and radiomics allow precise differentiation in brain tumors

by Karl Landsteiner University of Health SciencesGeneral diagram of the proposed radiomics and radiophysiomics approach, showing the major steps: MRI data acquisition, calculation of MRI biomarker map

Updated on: January 04,2024

Deep learning and radiomics allow precise differentiation in brain tumors

by Karl Landsteiner University of Health SciencesGeneral diagram of the proposed radiomics and radiophysiomics approach, showing the major steps: MRI data acquisition, calculation of MRI biomarker map

Updated on:January 04,2024