Meningioma molecular profile reliably predicts tumor recurrence

by Baylor College of MedicineCredit: CC0 Public DomainAlthough typically benign, about one-fifth of meningiomas, the most common primary brain tumors, recur despite complete surgical removal. The

Updated on: March 12,2024

Meningioma molecular profile reliably predicts tumor recurrence

by Baylor College of MedicineCredit: CC0 Public DomainAlthough typically benign, about one-fifth of meningiomas, the most common primary brain tumors, recur despite complete surgical removal. The

Updated on:March 12,2024

Fighting aggressive blood cancer ages and exhausts immune cells, study shows

byNottingham Trent UniversityGraphical abstract. Credit:Journal of Clinical Investigation(2022). DOI: 10.1172/JCI159579Scientists at Nottingham Trent University and John Hopkins Kimm

Updated on: January 22,2024

Fighting aggressive blood cancer ages and exhausts immune cells, study shows

byNottingham Trent UniversityGraphical abstract. Credit:Journal of Clinical Investigation(2022). DOI: 10.1172/JCI159579Scientists at Nottingham Trent University and John Hopkins Kimm

Updated on:January 22,2024

Tracing the footprints of a tumor—genomic 'scars' allow cancer profiling

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesHap1 Cells stained for different DNA damages (yellow = antibody against phosphorilated ATM; red = antibody against 53B

Updated on: April 01,2024

Tracing the footprints of a tumor—genomic 'scars' allow cancer profiling

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesHap1 Cells stained for different DNA damages (yellow = antibody against phosphorilated ATM; red = antibody against 53B

Updated on:April 01,2024

Genes with strong impact on menopause timing also link to cancer risk

byUniversity of ExeterCredit: Unsplash/CC0 Public DomainNew research has found four genes with some of the largest known effects on the timing of menopause discovered to date, providing new insi

Updated on: September 15,2024

Genes with strong impact on menopause timing also link to cancer risk

byUniversity of ExeterCredit: Unsplash/CC0 Public DomainNew research has found four genes with some of the largest known effects on the timing of menopause discovered to date, providing new insi

Updated on:September 15,2024

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer

by Impact Journals LLCVolcano plot of significant differentially expressed genes with the left volcano being the discovery cohort and validation cohort on the right. Credit:Oncotarget(2022

Updated on: January 02,2024

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer

by Impact Journals LLCVolcano plot of significant differentially expressed genes with the left volcano being the discovery cohort and validation cohort on the right. Credit:Oncotarget(2022

Updated on:January 02,2024

Research uncovers how to target 'sleeping' breast cancer cells and prevent relapse

byInstitute of Cancer ResearchModel: Endocrine therapy-induced dormancy is characterized by a consistent epigenetic reprogramming involving a global increase in histone repressive marks. The dor

Updated on: March 28,2024

Research uncovers how to target 'sleeping' breast cancer cells and prevent relapse

byInstitute of Cancer ResearchModel: Endocrine therapy-induced dormancy is characterized by a consistent epigenetic reprogramming involving a global increase in histone repressive marks. The dor

Updated on:March 28,2024

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells

by Impact JournalsCaspase inhibitors (CI) selectively protect normal cells from chemotherapy-induced apoptosis, without protection multidrug-resistant cancer cells. Flavopiridol (shown in red, as a cy

Updated on: January 15,2024

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells

by Impact JournalsCaspase inhibitors (CI) selectively protect normal cells from chemotherapy-induced apoptosis, without protection multidrug-resistant cancer cells. Flavopiridol (shown in red, as a cy

Updated on:January 15,2024

Newly discovered RNA molecules hold promise for detecting and treating esophageal cancer

by Bill Lubinger,Case Western Reserve UniversityA hairpin loop from a pre-mRNA. Highlighted are the nucleobases (green) and the ribose-phosphate backbone (blue). Note that this is a single stran

Updated on: April 29,2024

Newly discovered RNA molecules hold promise for detecting and treating esophageal cancer

by Bill Lubinger,Case Western Reserve UniversityA hairpin loop from a pre-mRNA. Highlighted are the nucleobases (green) and the ribose-phosphate backbone (blue). Note that this is a single stran

Updated on:April 29,2024

How post-feeding breasts bounce back from the brink of death to kick-start milk production

byUniversity of SheffieldDelayed alveolar regression in Rac1−/− glands in involution. (A-D) Carmine staining of whole-mounted mammary glands of WT (A, C) and Rac1−/− (B, D) mice at postlactation

Updated on: January 02,2024

How post-feeding breasts bounce back from the brink of death to kick-start milk production

byUniversity of SheffieldDelayed alveolar regression in Rac1−/− glands in involution. (A-D) Carmine staining of whole-mounted mammary glands of WT (A, C) and Rac1−/− (B, D) mice at postlactation

Updated on:January 02,2024

High-resolution brain tumor mapping reveals possible reason why some patients don't respond to new drug

byWeizmann Institute of ScienceGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.03.029The cells that make up cancerous brain tumors are extremely varied and sometimes

Updated on: September 10,2024

High-resolution brain tumor mapping reveals possible reason why some patients don't respond to new drug

byWeizmann Institute of ScienceGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.03.029The cells that make up cancerous brain tumors are extremely varied and sometimes

Updated on:September 10,2024

Researchers gain new insights into chromosome shortening and identify new potential cancer drug targets

by Institute of Cancer ResearchALT-reliant cells, with telomeres being marked by the green dots. Credit: Cancer and Genome Stability Team at the ICRA new study has provided insights into an impor

Updated on: January 28,2024

Researchers gain new insights into chromosome shortening and identify new potential cancer drug targets

by Institute of Cancer ResearchALT-reliant cells, with telomeres being marked by the green dots. Credit: Cancer and Genome Stability Team at the ICRA new study has provided insights into an impor

Updated on:January 28,2024

Are older women being over-screened for cervical cancer?

byUniversity of Illinois at ChicagoCredit: CC0 Public DomainA new study published inJAMA Internal Medicinesuggests that women over the age of 65 may be undergoing unnecessary cervica

Updated on: December 28,2023

Are older women being over-screened for cervical cancer?

byUniversity of Illinois at ChicagoCredit: CC0 Public DomainA new study published inJAMA Internal Medicinesuggests that women over the age of 65 may be undergoing unnecessary cervica

Updated on:December 28,2023