Cesarean section tied to higher risk for later leukemia in offspring

Elective cesarean section (CS) is associated with an increased risk for leukemia in offspring, according to a systematic review and meta-analysis published online Aug. 24 inHematological Oncolog

Updated on: January 02,2024 9

Cesarean section tied to higher risk for later leukemia in offspring

Elective cesarean section (CS) is associated with an increased risk for leukemia in offspring, according to a systematic review and meta-analysis published online Aug. 24 inHematological Oncolog

Updated on:January 02,2024 9

Unique insights into differences between primary and metastatic cancer by large-scale DNA data analyses

by Hartwig Medical FoundationInference of HLA-I tumor status with LILAC. a, Representation of the six immune escape pathways considered in the present study alongside their associated genes (adapted f

Updated on: January 07,2024 15

Unique insights into differences between primary and metastatic cancer by large-scale DNA data analyses

by Hartwig Medical FoundationInference of HLA-I tumor status with LILAC. a, Representation of the six immune escape pathways considered in the present study alongside their associated genes (adapted f

Updated on:January 07,2024 15

An elusive mechanism of wasting syndrome cachexia revealed

by Justin Jackson , Medical XpressOSM induces Eda2r expression in muscle and the depletion of OSMR protects from muscle wasting. a, Mouse primary myotubes were treated with recombinant TNFα, IL-6, LIF

Updated on: February 01,2024 16

An elusive mechanism of wasting syndrome cachexia revealed

by Justin Jackson , Medical XpressOSM induces Eda2r expression in muscle and the depletion of OSMR protects from muscle wasting. a, Mouse primary myotubes were treated with recombinant TNFα, IL-6, LIF

Updated on:February 01,2024 16

Researchers revisit potent drug as promising treatment for acute leukemia

by National University of SingaporeChemical screening using the GIMAP enhancer reporter system. (A) Overview of the chemical screening strategy. Using a liquid handling workstation, 2,961 compoun

Updated on: February 03,2024 11

Researchers revisit potent drug as promising treatment for acute leukemia

by National University of SingaporeChemical screening using the GIMAP enhancer reporter system. (A) Overview of the chemical screening strategy. Using a liquid handling workstation, 2,961 compoun

Updated on:February 03,2024 11

Researchers develop 'Goldilocks drug' to treat triple-negative breast cancer

by Mikayla Mace Kelley,University of ArizonacSNX1.3 competitively inhibits binding of EGFR to SNX1.ARibbon drawing of EGFR kinase domain (PDB ID 5CNO) and SNX1 Bar domain (PDB ID 4FZ

Updated on: February 20,2024 11

Researchers develop 'Goldilocks drug' to treat triple-negative breast cancer

by Mikayla Mace Kelley,University of ArizonacSNX1.3 competitively inhibits binding of EGFR to SNX1.ARibbon drawing of EGFR kinase domain (PDB ID 5CNO) and SNX1 Bar domain (PDB ID 4FZ

Updated on:February 20,2024 11

How 'paralyzed' immune cells can be reactivated against brain tumors

by German Cancer Research CenterGlioma of the left parietal lobe. CT scan with contrast enhancement. Credit: Mikhail Kalinin/CC BY-SA 3.0Brain tumor cells with a certain common mutation reprogram

Updated on: April 01,2024 11

How 'paralyzed' immune cells can be reactivated against brain tumors

by German Cancer Research CenterGlioma of the left parietal lobe. CT scan with contrast enhancement. Credit: Mikhail Kalinin/CC BY-SA 3.0Brain tumor cells with a certain common mutation reprogram

Updated on:April 01,2024 11

New therapeutic approach for the treatment of neuroblastoma in young children

by Jonas Machner, Universitätsmedizin HalleLead author Sven Hagemann is handling cell cultures. Credit: University Medicine HalleNeuroblastomas are tumors of the nervous system. They can form in many

Updated on: February 18,2024 17

New therapeutic approach for the treatment of neuroblastoma in young children

by Jonas Machner, Universitätsmedizin HalleLead author Sven Hagemann is handling cell cultures. Credit: University Medicine HalleNeuroblastomas are tumors of the nervous system. They can form in many

Updated on:February 18,2024 17

A myeloma-targeting monoclonal antibody offers new hope for treating multiple myeloma

by Osaka UniversitySummary of the research. Credit: Naoki HosenMultiple myeloma (MM) is a largely incurable cancer of plasma cells with an extremely poor prognosis. However, investigators from Ja

Updated on: May 07,2024 19

A myeloma-targeting monoclonal antibody offers new hope for treating multiple myeloma

by Osaka UniversitySummary of the research. Credit: Naoki HosenMultiple myeloma (MM) is a largely incurable cancer of plasma cells with an extremely poor prognosis. However, investigators from Ja

Updated on:May 07,2024 19

Study reveals mechanism linking heart disease to cancer development

byTel-Aviv UniversityCredit: CC0 Public DomainResearchers at Tel Aviv University (TAU) and the Leviev Cardiothoracic and Vascular Center at the Sheba Medical Center have found a mechanism respon

Updated on: April 28,2024 0

Study reveals mechanism linking heart disease to cancer development

byTel-Aviv UniversityCredit: CC0 Public DomainResearchers at Tel Aviv University (TAU) and the Leviev Cardiothoracic and Vascular Center at the Sheba Medical Center have found a mechanism respon

Updated on:April 28,2024 0

Leukemia treatment breakthrough for babies

by Hayley Jarvis,Brunel UniversityComparison of K562-t(7;12) transcriptional landscape with t(7;12) patient signatures. A 177-gene signature of t(7;12)-patient gene expression extrapolated from

Updated on: February 23,2024 16

Leukemia treatment breakthrough for babies

by Hayley Jarvis,Brunel UniversityComparison of K562-t(7;12) transcriptional landscape with t(7;12) patient signatures. A 177-gene signature of t(7;12)-patient gene expression extrapolated from

Updated on:February 23,2024 16

New immunotherapy holds promise for ovarian cancer

byKarolinska InstitutetIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous epithelium (right) a

Updated on: January 12,2024 10

New immunotherapy holds promise for ovarian cancer

byKarolinska InstitutetIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous epithelium (right) a

Updated on:January 12,2024 10

Study shows how to make (and destroy) a metastatic cancer cell

by CU Anschutz Medical CampusColorado study shows that inhibiting the lysosomal stage of autophagy (and not necessarily the action of the autophagosome) may kill metastatic cancer cells. Credit:

Updated on: May 31,2024 3

Study shows how to make (and destroy) a metastatic cancer cell

by CU Anschutz Medical CampusColorado study shows that inhibiting the lysosomal stage of autophagy (and not necessarily the action of the autophagosome) may kill metastatic cancer cells. Credit:

Updated on:May 31,2024 3