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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
Sub Categories on Oncology
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Research: Insufficient evidence to recommend low-dose CT screening in never smokers

Research: Insufficient evidence to recommend low-dose CT screening in never smokers

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainLung cancer remains the leading cause of cancer-related deaths worldwide. Detecting this disease in its early

Research: Insufficient evidence to recommend low-dose CT screening in never smokers

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainLung cancer remains the leading cause of cancer-related deaths worldwide. Detecting this disease in its early
Nirogacestat, a new desmoid tumor treatment, found to improve outcomes for people with sarcoma

Nirogacestat, a new desmoid tumor treatment, found to improve outcomes for people with sarcoma

byMemorial Sloan Kettering Cancer CenterCredit:New England Journal of Medicine(2023). DOI: 10.1056/NEJMoa2210140When Dana Avellino, now 36, first noticed a lump near her groin in the

Nirogacestat, a new desmoid tumor treatment, found to improve outcomes for people with sarcoma

byMemorial Sloan Kettering Cancer CenterCredit:New England Journal of Medicine(2023). DOI: 10.1056/NEJMoa2210140When Dana Avellino, now 36, first noticed a lump near her groin in the
Experimental AI method boosts doctors' ability to diagnose cancers and precancers of the esophagus

Experimental AI method boosts doctors' ability to diagnose cancers and precancers of the esophagus

by Delthia Ricks , Medical XpressEndoscopic photographs of lesions in three false-negative patients. Credit:Science Translational Medicine(2024). DOI: 10.1126/scitranslmed.adk5395Artificia

Experimental AI method boosts doctors' ability to diagnose cancers and precancers of the esophagus

by Delthia Ricks , Medical XpressEndoscopic photographs of lesions in three false-negative patients. Credit:Science Translational Medicine(2024). DOI: 10.1126/scitranslmed.adk5395Artificia
How do we know health screening programs work?

How do we know health screening programs work?

by Christian Yates,The ConversationLead-time bias can appear to make a treatment more effective than it actually is, if the perceived post-diagnosis survival time increases while the course of d

How do we know health screening programs work?

by Christian Yates,The ConversationLead-time bias can appear to make a treatment more effective than it actually is, if the perceived post-diagnosis survival time increases while the course of d
Medical scientists describe optimal immune therapeutic strategies for liver cancer

Medical scientists describe optimal immune therapeutic strategies for liver cancer

by The Korea Advanced Institute of Science and Technology (KAIST)Schematic image of study. Credit: KAISTKAIST medical scientists have presented a novel pathways involving T immune cell exhaustion

Medical scientists describe optimal immune therapeutic strategies for liver cancer

by The Korea Advanced Institute of Science and Technology (KAIST)Schematic image of study. Credit: KAISTKAIST medical scientists have presented a novel pathways involving T immune cell exhaustion
A new combination therapy regimen shows promising results for prostate cancer

A new combination therapy regimen shows promising results for prostate cancer

by Huntsman Cancer InstituteCredit: CC0 Public DomainTALAPRO-2, a study led by Neeraj Agarwal, MD, demonstrated that using TALZENNA, in combination with XTANDI, may reduce the risk of disease progress

A new combination therapy regimen shows promising results for prostate cancer

by Huntsman Cancer InstituteCredit: CC0 Public DomainTALAPRO-2, a study led by Neeraj Agarwal, MD, demonstrated that using TALZENNA, in combination with XTANDI, may reduce the risk of disease progress
Exploring how gene mutations in tumors impact radiation sensitivity

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad
Tackling resistance to HIF2 drugs with an RNA-based therapy

Tackling resistance to HIF2 drugs with an RNA-based therapy

byUT Southwestern Medical CenterDownregulation of HIF2α by ARO-HIF2 in patient tumor biopsies. Credit: Dr. Payal KapurExpected to be diagnosed in 2% of men and 1% of women in the U.S., kidney ca

Tackling resistance to HIF2 drugs with an RNA-based therapy

byUT Southwestern Medical CenterDownregulation of HIF2α by ARO-HIF2 in patient tumor biopsies. Credit: Dr. Payal KapurExpected to be diagnosed in 2% of men and 1% of women in the U.S., kidney ca
Convection-enhanced delivery of topotecan active in glioblastoma

Convection-enhanced delivery of topotecan active in glioblastoma

by Elana GotkineA subcutaneously implanted, catheter-pump system capable of chronic convection-enhanced delivery (CED) of topotecan is well tolerated and active for patients with recurrent glioblastom

Convection-enhanced delivery of topotecan active in glioblastoma

by Elana GotkineA subcutaneously implanted, catheter-pump system capable of chronic convection-enhanced delivery (CED) of topotecan is well tolerated and active for patients with recurrent glioblastom
The surprising link between circadian disruption and cancer may have to do with temperature

The surprising link between circadian disruption and cancer may have to do with temperature

byThe Scripps Research InstituteFor mice placed in ‘chronic jet lag’ (CJL) conditions, they showed a 68% increase in tumor burden when compared to mice placed in 12 hours of light, 12 hours of d

The surprising link between circadian disruption and cancer may have to do with temperature

byThe Scripps Research InstituteFor mice placed in ‘chronic jet lag’ (CJL) conditions, they showed a 68% increase in tumor burden when compared to mice placed in 12 hours of light, 12 hours of d
Researchers describe a new resistance mechanism

Researchers describe a new resistance mechanism

by IDIBELL-Bellvitge Biomedical Research InstituteDue to the treatment with the antibody against Semaphorin 4D (anti-Sema4D), changes occur in the tumor vasculature as well as a decrease in tumor

Researchers describe a new resistance mechanism

by IDIBELL-Bellvitge Biomedical Research InstituteDue to the treatment with the antibody against Semaphorin 4D (anti-Sema4D), changes occur in the tumor vasculature as well as a decrease in tumor
Research illuminates a therapeutic strategy to induce cancer cell death

Research illuminates a therapeutic strategy to induce cancer cell death

by Rachel Sauer,CU Anschutz Medical CampusCredit: CC0 Public DomainCancer is a disease driven by gene mutations. These mutated genes in cancer fall into two major categories: tumor suppressors a

Research illuminates a therapeutic strategy to induce cancer cell death

by Rachel Sauer,CU Anschutz Medical CampusCredit: CC0 Public DomainCancer is a disease driven by gene mutations. These mutated genes in cancer fall into two major categories: tumor suppressors a