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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Researchers reveal key mechanism of natural killer cell dysfunction

Researchers reveal key mechanism of natural killer cell dysfunction

by Liu Jia,Chinese Academy of SciencesIntratumoral NK cells lack abundant membrane protrusions. Credit:Nature Immunology(2023). DOI: 10.1038/s41590-023-01462-9A team has revealed the

Researchers reveal key mechanism of natural killer cell dysfunction

by Liu Jia,Chinese Academy of SciencesIntratumoral NK cells lack abundant membrane protrusions. Credit:Nature Immunology(2023). DOI: 10.1038/s41590-023-01462-9A team has revealed the
Research: Insufficient evidence to recommend low-dose CT screening in never smokers

Research: Insufficient evidence to recommend low-dose CT screening in never smokers

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainLung cancer remains the leading cause of cancer-related deaths worldwide. Detecting this disease in its early

Research: Insufficient evidence to recommend low-dose CT screening in never smokers

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainLung cancer remains the leading cause of cancer-related deaths worldwide. Detecting this disease in its early
Exploring ways to overcome cisplatin resistance and alleviate pain in cancer treatment

Exploring ways to overcome cisplatin resistance and alleviate pain in cancer treatment

by Korea University College of MedicineThe study reveals that the transcription factor NANOG activates the transient receptor potential vanilloid 1 (TRPV1)—causing neuropathic pain. TRPV1 further stim

Exploring ways to overcome cisplatin resistance and alleviate pain in cancer treatment

by Korea University College of MedicineThe study reveals that the transcription factor NANOG activates the transient receptor potential vanilloid 1 (TRPV1)—causing neuropathic pain. TRPV1 further stim
Examining a potential second generation epigenetic therapy for advanced solid tumors

Examining a potential second generation epigenetic therapy for advanced solid tumors

by Vall d'Hebron Institute of OncologyCredit: Unsplash/CC0 Public DomainPreliminary results of a first-in-human study show manageable toxicity and preliminary antitumor activity of a potential sec

Examining a potential second generation epigenetic therapy for advanced solid tumors

by Vall d'Hebron Institute of OncologyCredit: Unsplash/CC0 Public DomainPreliminary results of a first-in-human study show manageable toxicity and preliminary antitumor activity of a potential sec
Innovative test that detects complex DNA patterns may improve mesothelioma detection rate in blood

Innovative test that detects complex DNA patterns may improve mesothelioma detection rate in blood

by Susan Murphy,Mayo ClinicStudy design. Our study involved detecting junctions that result from chromosomal rearrangements, insertions and deletions in mesothelioma in Step 1, then designing pr

Innovative test that detects complex DNA patterns may improve mesothelioma detection rate in blood

by Susan Murphy,Mayo ClinicStudy design. Our study involved detecting junctions that result from chromosomal rearrangements, insertions and deletions in mesothelioma in Step 1, then designing pr
Team develops tools and techniques to explore cancer signals at the subcellular level

Team develops tools and techniques to explore cancer signals at the subcellular level

by Jerry Grillo,Georgia Institute of TechnologyGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104980This year, about 240,000 people in the U.S. will discover the

Team develops tools and techniques to explore cancer signals at the subcellular level

by Jerry Grillo,Georgia Institute of TechnologyGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104980This year, about 240,000 people in the U.S. will discover the
Microbiome: Scientists highlight role of harmful gut bacteria in fever afflicting cancer patients

Microbiome: Scientists highlight role of harmful gut bacteria in fever afflicting cancer patients

by Delthia Ricks , Medical XpressSchematic of histological quantification of the dense inner colonic mucus layer histologically, following PAS staining. Eight equally radially spaced sites are identif

Microbiome: Scientists highlight role of harmful gut bacteria in fever afflicting cancer patients

by Delthia Ricks , Medical XpressSchematic of histological quantification of the dense inner colonic mucus layer histologically, following PAS staining. Eight equally radially spaced sites are identif
Neoadjuvant nivolumab shows long-term benefit in patients with non–small cell lung cancer

Neoadjuvant nivolumab shows long-term benefit in patients with non–small cell lung cancer

byAmerican Association for Cancer ResearchA–D, Kaplan–Meier curves depicting the recurrence-free survival (A) and overall survival (B) for patients who underwent definitive resection after recei

Neoadjuvant nivolumab shows long-term benefit in patients with non–small cell lung cancer

byAmerican Association for Cancer ResearchA–D, Kaplan–Meier curves depicting the recurrence-free survival (A) and overall survival (B) for patients who underwent definitive resection after recei
A new treatment for acute myeloid leukemia could prove beneficial for even more people

A new treatment for acute myeloid leukemia could prove beneficial for even more people

by Peter MacCallum Cancer CentreAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainNew research published inScience Advancestoday conducted by researchers at Peter MacCallu

A new treatment for acute myeloid leukemia could prove beneficial for even more people

by Peter MacCallum Cancer CentreAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainNew research published inScience Advancestoday conducted by researchers at Peter MacCallu
Immunotherapy before surgery induces complete response in more than half of patients with common skin cancer

Immunotherapy before surgery induces complete response in more than half of patients with common skin cancer

by University of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainIn an international, multicenter Phase II clinical trial led by The University of Texas MD Anderson Cancer Center, 63.3

Immunotherapy before surgery induces complete response in more than half of patients with common skin cancer

by University of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainIn an international, multicenter Phase II clinical trial led by The University of Texas MD Anderson Cancer Center, 63.3
Research: Subset of breast cancers have two PIK3CA mutations on the same allele

Research: Subset of breast cancers have two PIK3CA mutations on the same allele

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA team of researchers affiliated with a large number of institutions in the U.S. has found that a subgroup of breast cancers have two PIK3CA mutat

Research: Subset of breast cancers have two PIK3CA mutations on the same allele

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA team of researchers affiliated with a large number of institutions in the U.S. has found that a subgroup of breast cancers have two PIK3CA mutat
Life-threatening side effects of novel cancer immunotherapies could be treatable

Life-threatening side effects of novel cancer immunotherapies could be treatable

byKarolinska InstitutetLaboratory tests after immune checkpoint inhibitor (ICI) treatment in a patient with metastatic renal cell carcinoma. (A) Routine blood tests for the indicated markers at

Life-threatening side effects of novel cancer immunotherapies could be treatable

byKarolinska InstitutetLaboratory tests after immune checkpoint inhibitor (ICI) treatment in a patient with metastatic renal cell carcinoma. (A) Routine blood tests for the indicated markers at