Supercharging CAR-T cells for cancer treatment

byEcole Polytechnique Federale de LausanneIL-10-expressing CAR T cells counter dysfunction in tumors.a, Schematic depicting the HER2 CAR and IL-10 HER2 CAR constructs; scFv, single-chain v

Updated on: January 26,2024 16

Supercharging CAR-T cells for cancer treatment

byEcole Polytechnique Federale de LausanneIL-10-expressing CAR T cells counter dysfunction in tumors.a, Schematic depicting the HER2 CAR and IL-10 HER2 CAR constructs; scFv, single-chain v

Updated on:January 26,2024 16

Study identifies link between DNA-protein binding, cancer onset

byStanford University Medical CenterResearchers at the Stanford University School of Medicine and their collaborators at other institutions have identified a link between how proteins bind to ou

Updated on: December 18,2023 22

Study identifies link between DNA-protein binding, cancer onset

byStanford University Medical CenterResearchers at the Stanford University School of Medicine and their collaborators at other institutions have identified a link between how proteins bind to ou

Updated on:December 18,2023 22

How do we overcome treatment resistance in a sarcoma cancer with already limited treatment options?

by Elena Daviter-Nowell,Institute of Cancer ResearchHistopathology image of leiomyosarcoma. Credit:Wikimedia Commons, CC-BY-SA 4.0Leiomyosarcoma is a type of soft tissue sarcoma that is ha

Updated on: January 10,2024 8

How do we overcome treatment resistance in a sarcoma cancer with already limited treatment options?

by Elena Daviter-Nowell,Institute of Cancer ResearchHistopathology image of leiomyosarcoma. Credit:Wikimedia Commons, CC-BY-SA 4.0Leiomyosarcoma is a type of soft tissue sarcoma that is ha

Updated on:January 10,2024 8

Lymphoma mutation yields super-competitive immune cells

by Heather Lindsey,Cornell UniversitySupercompetition in germinal centers leads to aggressive B cell lymphomas. GC B cells vigorously compete against each other to receive limiting T cell help,

Updated on: December 28,2023 10

Lymphoma mutation yields super-competitive immune cells

by Heather Lindsey,Cornell UniversitySupercompetition in germinal centers leads to aggressive B cell lymphomas. GC B cells vigorously compete against each other to receive limiting T cell help,

Updated on:December 28,2023 10

The molecules behind metastasis

by Greta Friar,Whitehead Institute for Biomedical ResearchBreast cancer stem cells (red) that have reached the lung begin to divide into clusters that could become metastatic tumors. Credit: Art

Updated on: January 21,2024 16

The molecules behind metastasis

by Greta Friar,Whitehead Institute for Biomedical ResearchBreast cancer stem cells (red) that have reached the lung begin to divide into clusters that could become metastatic tumors. Credit: Art

Updated on:January 21,2024 16

New treatment option for prostate cancer shows successful outcomes

by The Reis GroupCredit: CC0 Public DomainA minimally-invasive treatment using MRI and transurethral ultrasound instead of surgery or radiation is effective in treating prostate cancer, according to n

Updated on: March 30,2024 0

New treatment option for prostate cancer shows successful outcomes

by The Reis GroupCredit: CC0 Public DomainA minimally-invasive treatment using MRI and transurethral ultrasound instead of surgery or radiation is effective in treating prostate cancer, according to n

Updated on:March 30,2024 0

Race, income can determine blood cancer outcomes, studies show

by Ernie MundellIf someone is stricken with a blood cancer or life-threatening clot, they'll probably fare better if they are white and wealthy, three new studies show.The ongoing impact of patien

Updated on: January 22,2024 15

Race, income can determine blood cancer outcomes, studies show

by Ernie MundellIf someone is stricken with a blood cancer or life-threatening clot, they'll probably fare better if they are white and wealthy, three new studies show.The ongoing impact of patien

Updated on:January 22,2024 15

Exploring mini-labs as an alternative to animal testing for evaluating radiopharmaceuticals

byHelmholtz Association of German Research CentresMPS layout; red—media circuit with integrated pump; blue—pneumatic connectors; yellow—microwells for organoids; green—LUER-connectors). Credit:&

Updated on: January 07,2024 12

Exploring mini-labs as an alternative to animal testing for evaluating radiopharmaceuticals

byHelmholtz Association of German Research CentresMPS layout; red—media circuit with integrated pump; blue—pneumatic connectors; yellow—microwells for organoids; green—LUER-connectors). Credit:&

Updated on:January 07,2024 12

Collaborative study shows CAR-T cell therapy safe, effective even for high-risk patients

byUniversity of Miami Leonard M. Miller School of MedicineCredit: Pixabay/CC0 Public DomainCAR-T cell therapy is a safe and effective treatment for diffuse large B-cell lymphoma (DLBCL), even fo

Updated on: January 25,2024 24

Collaborative study shows CAR-T cell therapy safe, effective even for high-risk patients

byUniversity of Miami Leonard M. Miller School of MedicineCredit: Pixabay/CC0 Public DomainCAR-T cell therapy is a safe and effective treatment for diffuse large B-cell lymphoma (DLBCL), even fo

Updated on:January 25,2024 24

Exploring the biology of 'double positive' T cells

byLudwig Cancer ResearchCredit: CC0 Public DomainThe molecular markers CD4 and CD8—defining helper T cells and killer T cells, respectively—were once considered mutually exclusive. But "dou

Updated on: January 07,2024 25

Exploring the biology of 'double positive' T cells

byLudwig Cancer ResearchCredit: CC0 Public DomainThe molecular markers CD4 and CD8—defining helper T cells and killer T cells, respectively—were once considered mutually exclusive. But "dou

Updated on:January 07,2024 25

A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

byFriedrich–Alexander University Erlangen–NurnbergZeb1 regulates the expression of enzymes crucial for adjusting the PUFA:MUFA ratio in phospholipids. Credit:Nature Cell Biology(2024

Updated on: July 17,2024 0

A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

byFriedrich–Alexander University Erlangen–NurnbergZeb1 regulates the expression of enzymes crucial for adjusting the PUFA:MUFA ratio in phospholipids. Credit:Nature Cell Biology(2024

Updated on:July 17,2024 0

Physical exercise prevents nerve damage during chemotherapy, sports scientist shows

byUniversity of BaselSports therapy to combat side effects: Fiona Streckmann with a patient during a neurological examination. A tuning fork is used to test vibration sensation, which can be alt

Updated on: July 08,2024 0

Physical exercise prevents nerve damage during chemotherapy, sports scientist shows

byUniversity of BaselSports therapy to combat side effects: Fiona Streckmann with a patient during a neurological examination. A tuning fork is used to test vibration sensation, which can be alt

Updated on:July 08,2024 0