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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Double testing better at identifying bowel cancer

Double testing better at identifying bowel cancer

byUniversity of EdinburghReceiver operating characteristic (ROC) curve analysis for the detection of colorectal cancer between cohorts. Area under the curve 0.85 (95% c.i. 0.80 to 0.90) for the

Double testing better at identifying bowel cancer

byUniversity of EdinburghReceiver operating characteristic (ROC) curve analysis for the detection of colorectal cancer between cohorts. Area under the curve 0.85 (95% c.i. 0.80 to 0.90) for the
Cytokine mediates obesity-related factors linked to colorectal cancer

Cytokine mediates obesity-related factors linked to colorectal cancer

byMary Ann Liebert, IncCredit: Mary Ann Liebert, Inc., publishersA new study describes the mechanistic relationship between the cytokine interleukin-1ß, (IL-1ß) and obesity, showing that when IL

Cytokine mediates obesity-related factors linked to colorectal cancer

byMary Ann Liebert, IncCredit: Mary Ann Liebert, Inc., publishersA new study describes the mechanistic relationship between the cytokine interleukin-1ß, (IL-1ß) and obesity, showing that when IL
Researchers target mutation that leads to pancreatic cancer

Researchers target mutation that leads to pancreatic cancer

by Leslie Cantu,Medical University of South CarolinaCrystal structures of 12D5(K63S) in complex with KRAS(G12D)•GTPγS and with KRAS(G12D)•GDP. (A) A comparison of 12D5(K63S)–KRAS(G12D)•GTPγS (Le

Researchers target mutation that leads to pancreatic cancer

by Leslie Cantu,Medical University of South CarolinaCrystal structures of 12D5(K63S) in complex with KRAS(G12D)•GTPγS and with KRAS(G12D)•GDP. (A) A comparison of 12D5(K63S)–KRAS(G12D)•GTPγS (Le
Genetic discovery could improve treatment of colorectal cancer

Genetic discovery could improve treatment of colorectal cancer

by Rémi Carlier,Ecole Polytechnique Federale de LausannePOU5F1B differs from OCT4. a Representative immunofluorescence–confocal microscopy of POU5F1B-HA overexpressing SW480 cells, with DAPI in

Genetic discovery could improve treatment of colorectal cancer

by Rémi Carlier,Ecole Polytechnique Federale de LausannePOU5F1B differs from OCT4. a Representative immunofluorescence–confocal microscopy of POU5F1B-HA overexpressing SW480 cells, with DAPI in
U.S. cancer deaths decline overall, but prostate cancers make rebound

U.S. cancer deaths decline overall, but prostate cancers make rebound

by Dennis ThompsonCancer deaths continue to decline, dropping 33% since 1991 and saving an estimated 3.8 million lives, according to the American Cancer Society's annual statistics report.But indi

U.S. cancer deaths decline overall, but prostate cancers make rebound

by Dennis ThompsonCancer deaths continue to decline, dropping 33% since 1991 and saving an estimated 3.8 million lives, according to the American Cancer Society's annual statistics report.But indi
Examining how gender inequalities worsen women's access to cancer prevention, detection and care

Examining how gender inequalities worsen women's access to cancer prevention, detection and care

by LancetWomen, power, and cancer: a Lancet Commission highlights how, at all these intersections with cancer, women across the globe are subject to overlapping forms of discrimination and inequi

Examining how gender inequalities worsen women's access to cancer prevention, detection and care

by LancetWomen, power, and cancer: a Lancet Commission highlights how, at all these intersections with cancer, women across the globe are subject to overlapping forms of discrimination and inequi
Scientists discover mucus allows young pancreatic cancer cells to grow but may also prevent a deadly transformation

Scientists discover mucus allows young pancreatic cancer cells to grow but may also prevent a deadly transformation

FEBRUARY 28, 2024by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of a mouse's early-stage pancreatic tumor. CSHL scientists discovered that early pancreatic cancer cells depend

Scientists discover mucus allows young pancreatic cancer cells to grow but may also prevent a deadly transformation

FEBRUARY 28, 2024by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of a mouse's early-stage pancreatic tumor. CSHL scientists discovered that early pancreatic cancer cells depend
The role of p53 as a target for novel cancer therapies

The role of p53 as a target for novel cancer therapies

by Erika Rindsjö,Karolinska InstitutetComplex interplay between TP53-mutant cancer cells and their microenvironment. Credit:Nature Reviews Clinical Oncology(2023). DOI: 10.1038/s4157

The role of p53 as a target for novel cancer therapies

by Erika Rindsjö,Karolinska InstitutetComplex interplay between TP53-mutant cancer cells and their microenvironment. Credit:Nature Reviews Clinical Oncology(2023). DOI: 10.1038/s4157
CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A: Study

CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A: Study

by Higher Education PressCoactivator-associated arginine methyltransferase 1 (CARM1) was recruited by hypoxia-inducible factor 1 subunit alpha (HIF1A) to form a complex and transactivate CDK4 and HIF1

CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A: Study

by Higher Education PressCoactivator-associated arginine methyltransferase 1 (CARM1) was recruited by hypoxia-inducible factor 1 subunit alpha (HIF1A) to form a complex and transactivate CDK4 and HIF1
Patients with HPV-positive oropharynx cancer should receive chemoradiation

Patients with HPV-positive oropharynx cancer should receive chemoradiation

byEuropean Society for Medical OncologyProf Hisham Mehanna, Chair, Head and Neck Surgery, Institute of Cancer and Genomic Sciences, University of Birmingham, UK, study author. Credit: © European

Patients with HPV-positive oropharynx cancer should receive chemoradiation

byEuropean Society for Medical OncologyProf Hisham Mehanna, Chair, Head and Neck Surgery, Institute of Cancer and Genomic Sciences, University of Birmingham, UK, study author. Credit: © European
Novel radiotracer identifies critical cancer biomarker, opens door to new therapeutic target for solid tumors

Novel radiotracer identifies critical cancer biomarker, opens door to new therapeutic target for solid tumors

by Society of Nuclear Medicine and Molecular Imaging[18F]AlF-RESCA-T4 immuno-PET/CT imaging of patient with primary lung cancer. (A–C) Maximum-intensity projection (A) and fusion images (B and C) of [

Novel radiotracer identifies critical cancer biomarker, opens door to new therapeutic target for solid tumors

by Society of Nuclear Medicine and Molecular Imaging[18F]AlF-RESCA-T4 immuno-PET/CT imaging of patient with primary lung cancer. (A–C) Maximum-intensity projection (A) and fusion images (B and C) of [
Small-Volume Blood Collection Tubes Can Reduce Transfusions in Intensive Care

Small-Volume Blood Collection Tubes Can Reduce Transfusions in Intensive Care

January 2024Leah LawrenceNew data indicate that the use of tubes that automatically collect less blood in the intensive care unit (ICU) may decrease red blood cell (RBC) transfusions without affecting

Small-Volume Blood Collection Tubes Can Reduce Transfusions in Intensive Care

January 2024Leah LawrenceNew data indicate that the use of tubes that automatically collect less blood in the intensive care unit (ICU) may decrease red blood cell (RBC) transfusions without affecting