Researchers uncover potential biomarkers of positive response to immunotherapy

by Denise Heady,University of California, Los AngelesResponse to ICI or MAPKi therapy is associated with increased T cell infiltration and enhanced interferon gamma (IFNγ) pathway activity in th

Updated on: January 30,2024

Researchers uncover potential biomarkers of positive response to immunotherapy

by Denise Heady,University of California, Los AngelesResponse to ICI or MAPKi therapy is associated with increased T cell infiltration and enhanced interferon gamma (IFNγ) pathway activity in th

Updated on:January 30,2024

In breast-cancer prevention, race matters

by The Ohio State UniversityCredit: CC0 Public DomainAfrican-American women at high risk of breast cancer are less likely than white women to pursue potentially life-saving preventive care, and r

Updated on: April 22,2024

In breast-cancer prevention, race matters

by The Ohio State UniversityCredit: CC0 Public DomainAfrican-American women at high risk of breast cancer are less likely than white women to pursue potentially life-saving preventive care, and r

Updated on:April 22,2024

Researchers develop novel gold-nanocluster-based tumor radiodynamic therapy

by Zhang Nannan,Chinese Academy of SciencesGold-nanocluster-based radiodynamic therapy. Credit: IGDBRadiotherapy (RT) is a primary method of tumor treatment. However, in clinical practice, radio

Updated on: February 01,2024

Researchers develop novel gold-nanocluster-based tumor radiodynamic therapy

by Zhang Nannan,Chinese Academy of SciencesGold-nanocluster-based radiodynamic therapy. Credit: IGDBRadiotherapy (RT) is a primary method of tumor treatment. However, in clinical practice, radio

Updated on:February 01,2024

Researchers discover a new mechanism of cancer immune defense

by Universitätsmedizin MagdeburgGraphical summary of inflammatory cell death induction of MHC-deficient and IFN-unresponsive tumors by CD4+ T cells in cooperation with iNOS-expressing myeloid cells. C

Updated on: February 01,2024

Researchers discover a new mechanism of cancer immune defense

by Universitätsmedizin MagdeburgGraphical summary of inflammatory cell death induction of MHC-deficient and IFN-unresponsive tumors by CD4+ T cells in cooperation with iNOS-expressing myeloid cells. C

Updated on:February 01,2024

Multi-modal AI models for intermediate- to high-risk localized prostate cancer

by NRG OncologyCredit: Pixabay/CC0 Public DomainNRG Oncology investigators analyzed clinical and digital histopathology data from five Phase III prostate cancer trials (NRG/RTOG 9202, 9408, 9413, 9910

Updated on: January 30,2024

Multi-modal AI models for intermediate- to high-risk localized prostate cancer

by NRG OncologyCredit: Pixabay/CC0 Public DomainNRG Oncology investigators analyzed clinical and digital histopathology data from five Phase III prostate cancer trials (NRG/RTOG 9202, 9408, 9413, 9910

Updated on:January 30,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on: June 04,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on:June 04,2024

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on: April 07,2024

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on:April 07,2024

Patients coping with mesothelioma experienced higher levels of toxicity on CheckMate743 regimen than reported in trials

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainBased on results from the CheckMate743 trial, the dual regimen of ipilimumab and nivolumab is the standard of

Updated on: April 10,2024

Patients coping with mesothelioma experienced higher levels of toxicity on CheckMate743 regimen than reported in trials

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainBased on results from the CheckMate743 trial, the dual regimen of ipilimumab and nivolumab is the standard of

Updated on:April 10,2024

Unemployment due to brain or spine cancer is linked to more pain and depression

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople who are unemployed due to brain or spine cancer may experience more severe symptoms of pain, discomfort, anxiety and depres

Updated on: January 02,2024

Unemployment due to brain or spine cancer is linked to more pain and depression

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople who are unemployed due to brain or spine cancer may experience more severe symptoms of pain, discomfort, anxiety and depres

Updated on:January 02,2024

Docs should consider a patient's weight before prescribing new chemotherapy drugs

by Sharon Parmet,University of Illinois at ChicagoAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA new class of cancer drugs just now

Updated on: May 13,2024

Docs should consider a patient's weight before prescribing new chemotherapy drugs

by Sharon Parmet,University of Illinois at ChicagoAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA new class of cancer drugs just now

Updated on:May 13,2024

Genetic breast cancer study alters guidelines in Sweden

by Lund UniversityCredit: Pixabay/CC0 Public DomainBRCA1 and BRCA2 are well-known breast cancer genes associated with a significantly increased risk of hereditary breast and ovarian cancer. Howev

Updated on: February 01,2024

Genetic breast cancer study alters guidelines in Sweden

by Lund UniversityCredit: Pixabay/CC0 Public DomainBRCA1 and BRCA2 are well-known breast cancer genes associated with a significantly increased risk of hereditary breast and ovarian cancer. Howev

Updated on:February 01,2024

New study indicates treatment patterns, not genetics, drive prostate cancer disparities

by Sylvester Comprehensive Cancer CenterOverview of study design and overall genomic landscape (A) Study overview. The study comprised 11 741 patients with prostate cancer who underwent CGP to assess

Updated on: January 12,2024

New study indicates treatment patterns, not genetics, drive prostate cancer disparities

by Sylvester Comprehensive Cancer CenterOverview of study design and overall genomic landscape (A) Study overview. The study comprised 11 741 patients with prostate cancer who underwent CGP to assess

Updated on:January 12,2024