Marker for therapy response in acute myeloid leukemia identified

byGerman Cancer Research CenterCell line sensitivity and additional patient data. A IC50s for VEN of 19 AML cell lines classified as primitive (Prim-AML, n = 11) or monocytic (Mono-AML, n = 8) t

Updated on: December 21,2023

Marker for therapy response in acute myeloid leukemia identified

byGerman Cancer Research CenterCell line sensitivity and additional patient data. A IC50s for VEN of 19 AML cell lines classified as primitive (Prim-AML, n = 11) or monocytic (Mono-AML, n = 8) t

Updated on:December 21,2023

Newfound mechanism suggests drug combination could starve pancreatic cancer

byNYU Langone HealthPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteA new combination of treatments safely decreased growth of pan

Updated on: October 14,2023

Newfound mechanism suggests drug combination could starve pancreatic cancer

byNYU Langone HealthPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteA new combination of treatments safely decreased growth of pan

Updated on:October 14,2023

Multisite multiomic analysis reveals diverse resistance mechanisms in end-stage ovarian cancer

by Justin Jackson , Medical XpressThe clinical journey is shown for each patient, in 100 day intervals (x-axis), with the first tick referring to the day of first diagnostic information (surgery or CA

Updated on: December 21,2023

Multisite multiomic analysis reveals diverse resistance mechanisms in end-stage ovarian cancer

by Justin Jackson , Medical XpressThe clinical journey is shown for each patient, in 100 day intervals (x-axis), with the first tick referring to the day of first diagnostic information (surgery or CA

Updated on:December 21,2023

PAD4 inhibition in neutrophils halts cancer progression and metastasis

byThe Wistar InstituteCancer Cell Dividing. Credit: The Wistar InstituteResearchers in the laboratory of Yulia Nefedova, M.D., Ph.D., at The Wistar Institute and collaborators at Jubilant Therap

Updated on: December 17,2023

PAD4 inhibition in neutrophils halts cancer progression and metastasis

byThe Wistar InstituteCancer Cell Dividing. Credit: The Wistar InstituteResearchers in the laboratory of Yulia Nefedova, M.D., Ph.D., at The Wistar Institute and collaborators at Jubilant Therap

Updated on:December 17,2023

Sub-lobar surgery for peripheral non-small cell lung cancer non-inferior to lobectomy

by International Association for the Study of Lung CancerCancer cell during cell division. Credit: National Institutes of HealthA large international study of patients with non-small cell lung cancer

Updated on: December 18,2023

Sub-lobar surgery for peripheral non-small cell lung cancer non-inferior to lobectomy

by International Association for the Study of Lung CancerCancer cell during cell division. Credit: National Institutes of HealthA large international study of patients with non-small cell lung cancer

Updated on:December 18,2023

Multimodal sequencing achieves high-quality results from small volumes of frozen tumor specimens

byColumbia University School of Engineering and Applied ScienceA Circos plot representing the results of matched T-cell receptor sequencing collected on a patient undergoing anti-PD1 therapy. Co

Updated on: December 21,2023

Multimodal sequencing achieves high-quality results from small volumes of frozen tumor specimens

byColumbia University School of Engineering and Applied ScienceA Circos plot representing the results of matched T-cell receptor sequencing collected on a patient undergoing anti-PD1 therapy. Co

Updated on:December 21,2023

Are inflammatory bowel disease patients more at risk of colorectal cancer

In a recent study published in the journalFrontiers in Medicine, researchers analyzed data from a large cohort of inflammatory bowel disease (IBD) patients and compared the risk and frequency of

Updated on: October 30,2023

Are inflammatory bowel disease patients more at risk of colorectal cancer

In a recent study published in the journalFrontiers in Medicine, researchers analyzed data from a large cohort of inflammatory bowel disease (IBD) patients and compared the risk and frequency of

Updated on:October 30,2023

Research collaboration reveals promising drug candidate for treatment of blood cancers

by Children's Cancer Institute AustraliaCredit: CC0 Public DomainToday, OncoTartis, Inc. and Children's Cancer Institute jointly announced the publication of two research manuscripts in a lead

Updated on: December 20,2023

Research collaboration reveals promising drug candidate for treatment of blood cancers

by Children's Cancer Institute AustraliaCredit: CC0 Public DomainToday, OncoTartis, Inc. and Children's Cancer Institute jointly announced the publication of two research manuscripts in a lead

Updated on:December 20,2023

Black/white breast cancer subtype incidence in men differs from trends in women

byAmerican Cancer SocietyCredit: CC0 Public DomainIncidence rates for hormone receptor positive (HR+) breast cancers are considerably higher in black men than white men, in stark contrast to low

Updated on: December 22,2023

Black/white breast cancer subtype incidence in men differs from trends in women

byAmerican Cancer SocietyCredit: CC0 Public DomainIncidence rates for hormone receptor positive (HR+) breast cancers are considerably higher in black men than white men, in stark contrast to low

Updated on:December 22,2023

Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma

by Compuscript LtdGraphical abstract:Constitutively activated Gαq/11 proteins drive the vast majority of uveal melanoma (UM). GQ262 effectively combats UM both in vitro and in vivo by targeting Gαq/11

Updated on: December 21,2023

Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma

by Compuscript LtdGraphical abstract:Constitutively activated Gαq/11 proteins drive the vast majority of uveal melanoma (UM). GQ262 effectively combats UM both in vitro and in vivo by targeting Gαq/11

Updated on:December 21,2023

New classification system for tumors can guide diagnosis and treatment options for cancer

by Center for Genomic RegulationCredit: CC0 Public DomainBased on the largest study of cancer patients of its kind, scientists have created a new way of classifying tumours. Clinicians can use genome

Updated on: December 22,2023

New classification system for tumors can guide diagnosis and treatment options for cancer

by Center for Genomic RegulationCredit: CC0 Public DomainBased on the largest study of cancer patients of its kind, scientists have created a new way of classifying tumours. Clinicians can use genome

Updated on:December 22,2023

How a patient partnership is propelling cancer research

by Leah Eisenstadt,Broad Institute of MIT and HarvardCount Me In Director Nikhil Wagle and Strategic Advisor Corrie Painter. Credit: Broad Institute of MIT and HarvardIn the fall of 2018, cancer

Updated on: December 19,2023

How a patient partnership is propelling cancer research

by Leah Eisenstadt,Broad Institute of MIT and HarvardCount Me In Director Nikhil Wagle and Strategic Advisor Corrie Painter. Credit: Broad Institute of MIT and HarvardIn the fall of 2018, cancer

Updated on:December 19,2023