Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

by Southern Methodist UniversityLong exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMUResearchers at SMU's Center for Dr

Updated on: April 18,2024 11

Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

by Southern Methodist UniversityLong exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMUResearchers at SMU's Center for Dr

Updated on:April 18,2024 11

Patients coping with mesothelioma experienced higher levels of toxicity on CheckMate743 regimen than reported in trials

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainBased on results from the CheckMate743 trial, the dual regimen of ipilimumab and nivolumab is the standard of

Updated on: April 10,2024 16

Patients coping with mesothelioma experienced higher levels of toxicity on CheckMate743 regimen than reported in trials

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainBased on results from the CheckMate743 trial, the dual regimen of ipilimumab and nivolumab is the standard of

Updated on:April 10,2024 16

First line immunotherapy combination fails to improve overall survival in lung cancer

by European Society for Medical OncologyStudy author Dr Naiyer Rizvi, director of thoracic oncology and immunotherapeutics, Columbia University Medical Center, New York, US. Credit: © European So

Updated on: May 23,2024 6

First line immunotherapy combination fails to improve overall survival in lung cancer

by European Society for Medical OncologyStudy author Dr Naiyer Rizvi, director of thoracic oncology and immunotherapeutics, Columbia University Medical Center, New York, US. Credit: © European So

Updated on:May 23,2024 6

Molecular change to immunotherapy antibody could accelerate immune response to cancer

byWeizmann Institute of ScienceTissue sample of a particularly aggressive skin cancer reveals immune cells (yellow) that express on their surfaces a “brake pedal” receptor called FcgIIb (purple)

Updated on: January 02,2024 9

Molecular change to immunotherapy antibody could accelerate immune response to cancer

byWeizmann Institute of ScienceTissue sample of a particularly aggressive skin cancer reveals immune cells (yellow) that express on their surfaces a “brake pedal” receptor called FcgIIb (purple)

Updated on:January 02,2024 9

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Updated on: March 06,2024 16

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Updated on:March 06,2024 16

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p

Updated on: January 02,2024 6

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p

Updated on:January 02,2024 6

Researchers identify possible approach to prevent cancer from evolving to resist treatment

by University of California, Los AngelesSingle-agent inhibitory potencies in human melanoma, PDAC, and NSCLC clonogenic growth assays. A to G, Long-term clonogenic growth of indicated BRAFV600MUT

Updated on: February 18,2024 16

Researchers identify possible approach to prevent cancer from evolving to resist treatment

by University of California, Los AngelesSingle-agent inhibitory potencies in human melanoma, PDAC, and NSCLC clonogenic growth assays. A to G, Long-term clonogenic growth of indicated BRAFV600MUT

Updated on:February 18,2024 16

Extracellular cell matrix stiffness may induce drug resistance of breast cancer cells

by Shanghai Jiao Tong University Journal CenterCredit:Mechanobiology in Medicine(2023). DOI: 10.1016/j.mbm.2023.100023A new study, led by Prof. Liu from the department of pharmacy, Univers

Updated on: April 30,2024 0

Extracellular cell matrix stiffness may induce drug resistance of breast cancer cells

by Shanghai Jiao Tong University Journal CenterCredit:Mechanobiology in Medicine(2023). DOI: 10.1016/j.mbm.2023.100023A new study, led by Prof. Liu from the department of pharmacy, Univers

Updated on:April 30,2024 0

New imaging technology for diagnosing and treating bowel cancer patients

byUniversity of GlasgowRepresentative transverse PET images from each mouse model and tracer. Credit:Clinical Cancer Research(2024). DOI: 10.1158/1078-0432.CCR-23-1063Biopsies are cu

Updated on: March 30,2024 0

New imaging technology for diagnosing and treating bowel cancer patients

byUniversity of GlasgowRepresentative transverse PET images from each mouse model and tracer. Credit:Clinical Cancer Research(2024). DOI: 10.1158/1078-0432.CCR-23-1063Biopsies are cu

Updated on:March 30,2024 0

Tracing cancer back to birth uncovers promising biomarkers for prevention, targeted treatment of childhood leukemia

byMurdoch Children's Research InstituteDiscovery, validation and functional analysis of VTRNA2-1 methylation in association with pediatric pre-B ALL development. Credit:Molecular Cance

Updated on: November 11,2024 0

Tracing cancer back to birth uncovers promising biomarkers for prevention, targeted treatment of childhood leukemia

byMurdoch Children's Research InstituteDiscovery, validation and functional analysis of VTRNA2-1 methylation in association with pediatric pre-B ALL development. Credit:Molecular Cance

Updated on:November 11,2024 0

Researchers use machine learning to unlock the genomic code in clinical cancer samples

by University of HelsinkiMutational signatures of formalin exposure. a C>T FFPE-only mutation count increases with formalin fixation time. We observed this increase in both unrepaired and repa

Updated on: February 18,2024 20

Researchers use machine learning to unlock the genomic code in clinical cancer samples

by University of HelsinkiMutational signatures of formalin exposure. a C>T FFPE-only mutation count increases with formalin fixation time. We observed this increase in both unrepaired and repa

Updated on:February 18,2024 20

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Updated on: June 08,2024 8

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Updated on:June 08,2024 8