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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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New mathematical model shows promising results for prostate cancer treatment

New mathematical model shows promising results for prostate cancer treatment

byUniversity of PortsmouthGraphical abstract. Credit:Mathematical Biosciences(2022). DOI: 10.1016/j.mbs.2022.108940A new mathematical model which aims to optimize treatment for prost

New mathematical model shows promising results for prostate cancer treatment

byUniversity of PortsmouthGraphical abstract. Credit:Mathematical Biosciences(2022). DOI: 10.1016/j.mbs.2022.108940A new mathematical model which aims to optimize treatment for prost
Immune checkpoint blockade prior to surgery promising in multiple cancer types, finds study

Immune checkpoint blockade prior to surgery promising in multiple cancer types, finds study

byJohns Hopkins University School of MedicineThis graphic highlights the vast scientific research opportunities associated with neoadjuvant immune checkpoint blockade. Credit:Cancer CellTr

Immune checkpoint blockade prior to surgery promising in multiple cancer types, finds study

byJohns Hopkins University School of MedicineThis graphic highlights the vast scientific research opportunities associated with neoadjuvant immune checkpoint blockade. Credit:Cancer CellTr
Polyploidy study reveals why some cancers are resistant to therapeutic drugs

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea
Wildfire exposure decreases chances of survival for vulnerable cancer patients, study shows

Wildfire exposure decreases chances of survival for vulnerable cancer patients, study shows

by Rob Spahr,Emory UniversityCredit: Unsplash/CC0 Public DomainPeople exposed to a wildfire within a year after having lung cancer surgery have significantly lower chances of survival compared t

Wildfire exposure decreases chances of survival for vulnerable cancer patients, study shows

by Rob Spahr,Emory UniversityCredit: Unsplash/CC0 Public DomainPeople exposed to a wildfire within a year after having lung cancer surgery have significantly lower chances of survival compared t
Soluble immune checkpoint factors in blood as potential biomarkers of therapeutic efficacy for ICI cancer immunotherapy

Soluble immune checkpoint factors in blood as potential biomarkers of therapeutic efficacy for ICI cancer immunotherapy

by Kindai UniversityThe concentration of soluble PD-L1m PD-1, CTLA4 in plasma were highly correlated with the expression of genes associated with exhaustion in the peripheral CD8+T cells. R valu

Soluble immune checkpoint factors in blood as potential biomarkers of therapeutic efficacy for ICI cancer immunotherapy

by Kindai UniversityThe concentration of soluble PD-L1m PD-1, CTLA4 in plasma were highly correlated with the expression of genes associated with exhaustion in the peripheral CD8+T cells. R valu
An antenna for detecting breast cancer

An antenna for detecting breast cancer

by David Bradley,InderscienceCredit: CC0 Public DomainBreast cancer is a common illness around the world. It is the most common invasive of cancers in women and affects around one in eight and r

An antenna for detecting breast cancer

by David Bradley,InderscienceCredit: CC0 Public DomainBreast cancer is a common illness around the world. It is the most common invasive of cancers in women and affects around one in eight and r
Graph filtration learning reveals new dimensions in hepatocellular carcinoma imaging

Graph filtration learning reveals new dimensions in hepatocellular carcinoma imaging

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial was published inOncotarget, titled "Beyond pixels: Graph filtration learning unveils new dimensions in hepatocellular

Graph filtration learning reveals new dimensions in hepatocellular carcinoma imaging

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial was published inOncotarget, titled "Beyond pixels: Graph filtration learning unveils new dimensions in hepatocellular
Novel approach to study hypoxia enables identification of a marker for ovarian cancers

Novel approach to study hypoxia enables identification of a marker for ovarian cancers

by Myreille Larouche,University of MontrealLong-term severe hypoxia adaptation induces EMT-like morphological changes. Credit:Cancer Gene Therapy(2024). DOI: 10.1038/s41417-024-00795

Novel approach to study hypoxia enables identification of a marker for ovarian cancers

by Myreille Larouche,University of MontrealLong-term severe hypoxia adaptation induces EMT-like morphological changes. Credit:Cancer Gene Therapy(2024). DOI: 10.1038/s41417-024-00795
More women in US receive 3-D mammography but disparities remain

More women in US receive 3-D mammography but disparities remain

by Yale UniversityCredit: CC0 Public DomainUse of 3-D mammography, an advanced form of breast cancer screening, has risen rapidly in recent years, according to Yale researchers in a new study. Bu

More women in US receive 3-D mammography but disparities remain

by Yale UniversityCredit: CC0 Public DomainUse of 3-D mammography, an advanced form of breast cancer screening, has risen rapidly in recent years, according to Yale researchers in a new study. Bu
Assay to ID anticancer reagents targeting fructose-1,6-bisphosphate aldolase

Assay to ID anticancer reagents targeting fructose-1,6-bisphosphate aldolase

by SLAS (Society for Laboratory Automation and Screening)ALDOA catalyzes the reversible aldol cleavage of fructose-1,6-bisphosphate (F-1,6-BP) into D-Glyceraldehyde-3-phosphate (GAP) and dihydroxyacet

Assay to ID anticancer reagents targeting fructose-1,6-bisphosphate aldolase

by SLAS (Society for Laboratory Automation and Screening)ALDOA catalyzes the reversible aldol cleavage of fructose-1,6-bisphosphate (F-1,6-BP) into D-Glyceraldehyde-3-phosphate (GAP) and dihydroxyacet
Major progress in curing brain tumors by blocking certain functions in cells with a docked molecule

Major progress in curing brain tumors by blocking certain functions in cells with a docked molecule

by University of GothenburgThe researchers’ molecule Z4P inhibits one of the mechanisms that regulate protein production in a cancer cell. This inhibition causes the cancer cell to die. Three pic

Major progress in curing brain tumors by blocking certain functions in cells with a docked molecule

by University of GothenburgThe researchers’ molecule Z4P inhibits one of the mechanisms that regulate protein production in a cancer cell. This inhibition causes the cancer cell to die. Three pic
Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l