On-the-move cancer cells prefer a 'comfort cruise,' follow predictable paths of least resistance

by Spencer Turney,Vanderbilt UniversityA cancer cell migrating through a collagen track with fluorescent biomarkers showing cellular energy levels assigned a hue on the color spectrum from purpl

Updated on: May 13,2024

On-the-move cancer cells prefer a 'comfort cruise,' follow predictable paths of least resistance

by Spencer Turney,Vanderbilt UniversityA cancer cell migrating through a collagen track with fluorescent biomarkers showing cellular energy levels assigned a hue on the color spectrum from purpl

Updated on:May 13,2024

Researchers use X-ray spectroscopy to explain why FLASH cancer therapy is so effective

by American Crystallographic Association (ACA)Overhead view of the XFMS experimental setup: A syringe pump pushes samples (proteins or peptides) through a capillary (blue tubing in the figure) and out

Updated on: February 18,2024

Researchers use X-ray spectroscopy to explain why FLASH cancer therapy is so effective

by American Crystallographic Association (ACA)Overhead view of the XFMS experimental setup: A syringe pump pushes samples (proteins or peptides) through a capillary (blue tubing in the figure) and out

Updated on:February 18,2024

Study successfully mimics complex neuroblastoma vasculature on a chip to explore treatments

by Institute for Bioengineering of CataloniaGraphical abstract. Credit:Cancers(2024). DOI: 10.3390/cancers16051060Neuroblastoma, one of the most common childhood cancers, is classified as

Updated on: March 30,2024

Study successfully mimics complex neuroblastoma vasculature on a chip to explore treatments

by Institute for Bioengineering of CataloniaGraphical abstract. Credit:Cancers(2024). DOI: 10.3390/cancers16051060Neuroblastoma, one of the most common childhood cancers, is classified as

Updated on:March 30,2024

Researchers explore why patients don't follow up with their doctors after receiving a positive colorectal cancer test

by American Academy of Family PhysiciansReasons for no colonoscopy after an unfavorable screening result in Dutch colorectal cancer screening: a nation-wise questionnaire. Credit:The Annals

Updated on: February 01,2024

Researchers explore why patients don't follow up with their doctors after receiving a positive colorectal cancer test

by American Academy of Family PhysiciansReasons for no colonoscopy after an unfavorable screening result in Dutch colorectal cancer screening: a nation-wise questionnaire. Credit:The Annals

Updated on:February 01,2024

Substance in the blood is found to increase as early as two years before diagnosis of pancreatic cancer

by Ola Nilsson,Umea UniversitySeparating future PDAC cases from controls in pre-diagnostic and diagnostic samples with a cross-sectional analysis. Box plots of the individual marker concentratio

Updated on: February 01,2024

Substance in the blood is found to increase as early as two years before diagnosis of pancreatic cancer

by Ola Nilsson,Umea UniversitySeparating future PDAC cases from controls in pre-diagnostic and diagnostic samples with a cross-sectional analysis. Box plots of the individual marker concentratio

Updated on:February 01,2024

Understanding the role of cancer's circular genome in tumor evolution

byQueen Mary, University of LondonOverview of strategies to develop and test rules of ecDNA behavior with mathematical modeling, computer simulations, cell line and patient data. Credit:Na

Updated on: December 28,2023

Understanding the role of cancer's circular genome in tumor evolution

byQueen Mary, University of LondonOverview of strategies to develop and test rules of ecDNA behavior with mathematical modeling, computer simulations, cell line and patient data. Credit:Na

Updated on:December 28,2023

Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on: September 28,2024

Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on:September 28,2024

Beating cancer-related fatigue with personalized interventions

byUniversity of TwenteFlow diagram of selection of eligible studies. Credit:European Journal of Cancer Care(2022). DOI: 10.1111/ecc.13754After diagnosis and treatment of breast cance

Updated on: January 07,2024

Beating cancer-related fatigue with personalized interventions

byUniversity of TwenteFlow diagram of selection of eligible studies. Credit:European Journal of Cancer Care(2022). DOI: 10.1111/ecc.13754After diagnosis and treatment of breast cance

Updated on:January 07,2024

Tumor macrophage marker offers unique target for treatment

by National Institutes of HealthA nanoparticle attached to CRV (CRV-NP) specifically homed to macrophages in breast tumors in mice (yellow arrow) and did not home to spleen, lung or heart. Nanopa

Updated on: April 09,2024

Tumor macrophage marker offers unique target for treatment

by National Institutes of HealthA nanoparticle attached to CRV (CRV-NP) specifically homed to macrophages in breast tumors in mice (yellow arrow) and did not home to spleen, lung or heart. Nanopa

Updated on:April 09,2024

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on: April 23,2024

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on:April 23,2024

Seeking microscopic clues to beating deadly brain tumors

by Hackensack Meridian HealthH&E stained sections of patient glioblastoma samples. Higher magnifcation of representative regions are shown in the colored boxes. Histologic features include low (bl

Updated on: January 23,2024

Seeking microscopic clues to beating deadly brain tumors

by Hackensack Meridian HealthH&E stained sections of patient glioblastoma samples. Higher magnifcation of representative regions are shown in the colored boxes. Histologic features include low (bl

Updated on:January 23,2024

Simple test could lead to more personalized treatment of rare ovarian cancer

by University of New South WalesKaplan Meier curves of overall survival of ‘high’, ‘medium’ and ‘low’ tertiles of mRNA expression of THSB2 (left) and TAGLN (right) in MOC (n=185). Credit:Cl

Updated on: January 29,2024

Simple test could lead to more personalized treatment of rare ovarian cancer

by University of New South WalesKaplan Meier curves of overall survival of ‘high’, ‘medium’ and ‘low’ tertiles of mRNA expression of THSB2 (left) and TAGLN (right) in MOC (n=185). Credit:Cl

Updated on:January 29,2024