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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Study sends strong signal not to sequence immune checkpoint inhibitors in advanced kidney cancer

Study sends strong signal not to sequence immune checkpoint inhibitors in advanced kidney cancer

byDana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainPatients with advanced kidney cancer are routinely given immune checkpoint inhibitors (ICIs) as first-line treatment. The CONTACT-0

Study sends strong signal not to sequence immune checkpoint inhibitors in advanced kidney cancer

byDana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainPatients with advanced kidney cancer are routinely given immune checkpoint inhibitors (ICIs) as first-line treatment. The CONTACT-0
Study reveals persistent cancer disparities in Appalachian Kentucky

Study reveals persistent cancer disparities in Appalachian Kentucky

by Elizabeth Chapin,University of KentuckyCredit: Pixabay/CC0 Public DomainA recent University of Kentucky Markey Cancer Center study published inThe Journal of Rural Healthsheds lig

Study reveals persistent cancer disparities in Appalachian Kentucky

by Elizabeth Chapin,University of KentuckyCredit: Pixabay/CC0 Public DomainA recent University of Kentucky Markey Cancer Center study published inThe Journal of Rural Healthsheds lig
Immune system B-cells can help predict HER2-positive breast cancer treatment response

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce
Preclinical characterization of therapeutic antibodies

Preclinical characterization of therapeutic antibodies

by Rapamycin PressSchematic of experimental procedures for generation of novel anti-Sonic Hedgehog (Shh) candidate therapeutic antibodies directed at the carboxy (C)-terminal. (A) Two synthetic peptid

Preclinical characterization of therapeutic antibodies

by Rapamycin PressSchematic of experimental procedures for generation of novel anti-Sonic Hedgehog (Shh) candidate therapeutic antibodies directed at the carboxy (C)-terminal. (A) Two synthetic peptid
Effectiveness of a new bladder cancer treatment demonstrated

Effectiveness of a new bladder cancer treatment demonstrated

by IMIM (Hospital del Mar Medical Research Institute)Credit: IMIMResearchers from the Molecular Cancer group at the Hospital del Mar Medical Research Institute (IMIM) and doctors from Hospital del Mar

Effectiveness of a new bladder cancer treatment demonstrated

by IMIM (Hospital del Mar Medical Research Institute)Credit: IMIMResearchers from the Molecular Cancer group at the Hospital del Mar Medical Research Institute (IMIM) and doctors from Hospital del Mar
New class of drugs could treat ovarian cancer

New class of drugs could treat ovarian cancer

by Mike Addelman,University of ManchesterIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous ep

New class of drugs could treat ovarian cancer

by Mike Addelman,University of ManchesterIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous ep
Solving the mystery of NPM1 in acute myeloid leukemia

Solving the mystery of NPM1 in acute myeloid leukemia

by Allison Mickey,Baylor College of MedicineDr. Margaret Goodell, the corresponding author of this work. Credit: Baylor College of MedicineAlthough it has long been recognized that mutations of

Solving the mystery of NPM1 in acute myeloid leukemia

by Allison Mickey,Baylor College of MedicineDr. Margaret Goodell, the corresponding author of this work. Credit: Baylor College of MedicineAlthough it has long been recognized that mutations of
Fighting cancer one cell at a time

Fighting cancer one cell at a time

by Agency for Science, Technology and Research (A*STAR), SingaporeDrug-induced stem-cell switch (from Sox2 to Sox9) activates epigenetic re-programming driving tumour evolution in squamous cell c

Fighting cancer one cell at a time

by Agency for Science, Technology and Research (A*STAR), SingaporeDrug-induced stem-cell switch (from Sox2 to Sox9) activates epigenetic re-programming driving tumour evolution in squamous cell c
Researchers uncover how breast cancer cells become resistant to therapy

Researchers uncover how breast cancer cells become resistant to therapy

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainAbout one-fourth of recurrent estrogen receptor-positive (ER+) breast cancers lose ER expression, which renders them res

Researchers uncover how breast cancer cells become resistant to therapy

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainAbout one-fourth of recurrent estrogen receptor-positive (ER+) breast cancers lose ER expression, which renders them res
New tool helps find genetic culprits in cancer's spread

New tool helps find genetic culprits in cancer's spread

by Bill Hathaway,Yale UniversityYale researchers developed a new approach to simultaneously investigate hundreds of mutation combinations for their ability to drive lung metastasis. Credit: Yale

New tool helps find genetic culprits in cancer's spread

by Bill Hathaway,Yale UniversityYale researchers developed a new approach to simultaneously investigate hundreds of mutation combinations for their ability to drive lung metastasis. Credit: Yale
Supercharging immunotherapy to stop breast cancer from spreading to the lung

Supercharging immunotherapy to stop breast cancer from spreading to the lung

byUniversity of GlasgowGraphical abstract. Credit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20211431Breast cancer immunotherapy could be more effective if an immune ce

Supercharging immunotherapy to stop breast cancer from spreading to the lung

byUniversity of GlasgowGraphical abstract. Credit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20211431Breast cancer immunotherapy could be more effective if an immune ce
ACP issues guidance statement for breast cancer screening of average-risk women

ACP issues guidance statement for breast cancer screening of average-risk women

by American College of PhysiciansThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by T

ACP issues guidance statement for breast cancer screening of average-risk women

by American College of PhysiciansThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by T