Soluble immune checkpoint factors in blood as potential biomarkers of therapeutic efficacy for ICI cancer immunotherapy

by Kindai UniversityThe concentration of soluble PD-L1m PD-1, CTLA4 in plasma were highly correlated with the expression of genes associated with exhaustion in the peripheral CD8+T cells. R valu

Updated on: April 06,2024 0

Soluble immune checkpoint factors in blood as potential biomarkers of therapeutic efficacy for ICI cancer immunotherapy

by Kindai UniversityThe concentration of soluble PD-L1m PD-1, CTLA4 in plasma were highly correlated with the expression of genes associated with exhaustion in the peripheral CD8+T cells. R valu

Updated on:April 06,2024 0

Drug-like molecules show early success in targeting breast cancer brain metastases

byDrexel UniversityComputational pipeline and predicted drug-like properties for the discovery of AD-2441 and its analogs. Credit:Frontiers in Pharmacology(2024). DOI: 10.3389/fphar.

Updated on: August 01,2024 0

Drug-like molecules show early success in targeting breast cancer brain metastases

byDrexel UniversityComputational pipeline and predicted drug-like properties for the discovery of AD-2441 and its analogs. Credit:Frontiers in Pharmacology(2024). DOI: 10.3389/fphar.

Updated on:August 01,2024 0

Study sheds light on the function of a long-mysterious PCSK9 mutation

by American Society for Biochemistry and Molecular BiologyCredit: CC0 Public DomainHigh levels of low-density lipoproteins, parcels of lipids and protein that carry cholesterol, are a leading ris

Updated on: April 18,2024 18

Study sheds light on the function of a long-mysterious PCSK9 mutation

by American Society for Biochemistry and Molecular BiologyCredit: CC0 Public DomainHigh levels of low-density lipoproteins, parcels of lipids and protein that carry cholesterol, are a leading ris

Updated on:April 18,2024 18

First line immunotherapy combination fails to improve overall survival in lung cancer

by European Society for Medical OncologyStudy author Dr Naiyer Rizvi, director of thoracic oncology and immunotherapeutics, Columbia University Medical Center, New York, US. Credit: © European So

Updated on: May 23,2024 6

First line immunotherapy combination fails to improve overall survival in lung cancer

by European Society for Medical OncologyStudy author Dr Naiyer Rizvi, director of thoracic oncology and immunotherapeutics, Columbia University Medical Center, New York, US. Credit: © European So

Updated on:May 23,2024 6

Novel machine-learning blood test detects cancers with genome-wide mutations in single molecules of cell-free DNA

by Amy Mone,Johns Hopkins UniversitySchematic of overall approach for cancer detection using single-molecule cfDNA sequencing. Credit:Nature Genetics(2023). DOI: 10.1038/s41588-023-0

Updated on: January 30,2024 15

Novel machine-learning blood test detects cancers with genome-wide mutations in single molecules of cell-free DNA

by Amy Mone,Johns Hopkins UniversitySchematic of overall approach for cancer detection using single-molecule cfDNA sequencing. Credit:Nature Genetics(2023). DOI: 10.1038/s41588-023-0

Updated on:January 30,2024 15

The hidden challenge: Imaging perineural invasion in head and neck tumors

by Association of Basic Medical Sciences of FBIHA. 39-year-old male diagnosed with adenoid cystic carcinoma of maxillary sinus, with multiple extensions. Clinically: Right abducens nerve palsy, d

Updated on: February 24,2024 19

The hidden challenge: Imaging perineural invasion in head and neck tumors

by Association of Basic Medical Sciences of FBIHA. 39-year-old male diagnosed with adenoid cystic carcinoma of maxillary sinus, with multiple extensions. Clinically: Right abducens nerve palsy, d

Updated on:February 24,2024 19

Vitamin A derivative selectively kills liver cancer stem cells

by RIKENRetinol or Vitamin A 3D space model (balls model). Credit: YassineMrabet, Wikipedia.Acyclic retinoid, an artificial compound derived from vitamin A, has been found to prevent the recurren

Updated on: March 06,2024 16

Vitamin A derivative selectively kills liver cancer stem cells

by RIKENRetinol or Vitamin A 3D space model (balls model). Credit: YassineMrabet, Wikipedia.Acyclic retinoid, an artificial compound derived from vitamin A, has been found to prevent the recurren

Updated on:March 06,2024 16

Long-term survey reveals worsening death rate for oral cancer in Queensland

by James Cook UniversityTrends in number of cases and number of deaths during the 36-year period. Credit:Journal of Oral Pathology & Medicine(2023). DOI: 10.1111/jop.13421A study

Updated on: January 30,2024 10

Long-term survey reveals worsening death rate for oral cancer in Queensland

by James Cook UniversityTrends in number of cases and number of deaths during the 36-year period. Credit:Journal of Oral Pathology & Medicine(2023). DOI: 10.1111/jop.13421A study

Updated on:January 30,2024 10

New study shows Medicaid expansion associated with increase in palliative care for patients with advanced cancers

byAmerican Cancer SocietyMore people with advanced cancers in the United States received critical palliative care services, according to new findings by researchers at the American Cancer Societ

Updated on: January 12,2024 12

New study shows Medicaid expansion associated with increase in palliative care for patients with advanced cancers

byAmerican Cancer SocietyMore people with advanced cancers in the United States received critical palliative care services, according to new findings by researchers at the American Cancer Societ

Updated on:January 12,2024 12

Bacteria subtype linked to growth in up to 50% of human colorectal cancers, researchers report

byFred Hutchinson Cancer CenterA microscope image shows a human colorectal cancer tumor with Fusobacterium nucleatum stained in a red-purple color. The bacterium is commonly found in people'

Updated on: March 30,2024 0

Bacteria subtype linked to growth in up to 50% of human colorectal cancers, researchers report

byFred Hutchinson Cancer CenterA microscope image shows a human colorectal cancer tumor with Fusobacterium nucleatum stained in a red-purple color. The bacterium is commonly found in people'

Updated on:March 30,2024 0

Supporting smokers with new lung health checks could save thousands of lives

by University of NottinghamCredit: Unsplash/CC0 Public DomainResearchers and national cancer charities strongly welcome the UK Government's decision to back National Screening Committee recom

Updated on: January 30,2024 14

Supporting smokers with new lung health checks could save thousands of lives

by University of NottinghamCredit: Unsplash/CC0 Public DomainResearchers and national cancer charities strongly welcome the UK Government's decision to back National Screening Committee recom

Updated on:January 30,2024 14

Researchers develop novel gold-nanocluster-based tumor radiodynamic therapy

by Zhang Nannan,Chinese Academy of SciencesGold-nanocluster-based radiodynamic therapy. Credit: IGDBRadiotherapy (RT) is a primary method of tumor treatment. However, in clinical practice, radio

Updated on: February 01,2024 12

Researchers develop novel gold-nanocluster-based tumor radiodynamic therapy

by Zhang Nannan,Chinese Academy of SciencesGold-nanocluster-based radiodynamic therapy. Credit: IGDBRadiotherapy (RT) is a primary method of tumor treatment. However, in clinical practice, radio

Updated on:February 01,2024 12