Polybrominated diphenyl ether linked to increased risk for cancer mortality

by Elana GotkinePolybrominated diphenyl ether (PBDE) exposure is associated with an increased risk for cancer mortality, according to a studypublishedinJAMA Network Open.Buyun Liu, M

Updated on: April 06,2024

Polybrominated diphenyl ether linked to increased risk for cancer mortality

by Elana GotkinePolybrominated diphenyl ether (PBDE) exposure is associated with an increased risk for cancer mortality, according to a studypublishedinJAMA Network Open.Buyun Liu, M

Updated on:April 06,2024

Researchers uncover new targets for breast cancers resistant to standard therapies

by Leslie Cantu,Medical University of South CarolinaSOC therapy commonly induces DNA damage, BRCAness and toxic PARP1 trapping, leading to transcriptional blockage and growth inhibition in ER+ b

Updated on: June 22,2024

Researchers uncover new targets for breast cancers resistant to standard therapies

by Leslie Cantu,Medical University of South CarolinaSOC therapy commonly induces DNA damage, BRCAness and toxic PARP1 trapping, leading to transcriptional blockage and growth inhibition in ER+ b

Updated on:June 22,2024

Researchers develop method for identifying aggressive breast cancer drivers

by University of North Carolina at Chapel Hill School of MedicineUNC Lineberger’s Xian Chen, PhD. Credit: University of North Carolina at Chapel Hill School of MedicinePrecision cancer medicine r

Updated on: June 08,2024

Researchers develop method for identifying aggressive breast cancer drivers

by University of North Carolina at Chapel Hill School of MedicineUNC Lineberger’s Xian Chen, PhD. Credit: University of North Carolina at Chapel Hill School of MedicinePrecision cancer medicine r

Updated on:June 08,2024

Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

by Strata OncologyDevelopment of an integrative immunotherapy response score (IRS) model to stratify PD-(L)1 therapy benefit in patients with advanced solid tumors.aReal-world treatment an

Updated on: February 03,2024

Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

by Strata OncologyDevelopment of an integrative immunotherapy response score (IRS) model to stratify PD-(L)1 therapy benefit in patients with advanced solid tumors.aReal-world treatment an

Updated on:February 03,2024

Researchers make next move in the fight against ovarian cancer

by University of Arizona College of EngineeringGraphic representation of falloposcope image resolution on the University of Arizona's "Block A." Credit: University of ArizonaOvarian canc

Updated on: June 04,2024

Researchers make next move in the fight against ovarian cancer

by University of Arizona College of EngineeringGraphic representation of falloposcope image resolution on the University of Arizona's "Block A." Credit: University of ArizonaOvarian canc

Updated on:June 04,2024

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i

Updated on: June 08,2024

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i

Updated on:June 08,2024

Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

by Southern Methodist UniversityLong exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMUResearchers at SMU's Center for Dr

Updated on: April 18,2024

Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

by Southern Methodist UniversityLong exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMUResearchers at SMU's Center for Dr

Updated on:April 18,2024

New regulator in aggressive breast cancer cells discovered

by Leibniz Institute on AgingThe protein TRPS1 controls the activity of the YAP protein in breast cancer. If YAP activity is downregulated, the survival prognosis for patients is reduced. If TRPS1 is

Updated on: April 22,2024

New regulator in aggressive breast cancer cells discovered

by Leibniz Institute on AgingThe protein TRPS1 controls the activity of the YAP protein in breast cancer. If YAP activity is downregulated, the survival prognosis for patients is reduced. If TRPS1 is

Updated on:April 22,2024

Growing microtumors in a dish helps rapidly identify genes that drive tumor growth

by Emily Stone,University of Illinois at ChicagoCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113355Researchers have identified a new way to screen genes that cause several d

Updated on: April 22,2024

Growing microtumors in a dish helps rapidly identify genes that drive tumor growth

by Emily Stone,University of Illinois at ChicagoCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113355Researchers have identified a new way to screen genes that cause several d

Updated on:April 22,2024

Genetic breast cancer study alters guidelines in Sweden

by Lund UniversityCredit: Pixabay/CC0 Public DomainBRCA1 and BRCA2 are well-known breast cancer genes associated with a significantly increased risk of hereditary breast and ovarian cancer. Howev

Updated on: February 01,2024

Genetic breast cancer study alters guidelines in Sweden

by Lund UniversityCredit: Pixabay/CC0 Public DomainBRCA1 and BRCA2 are well-known breast cancer genes associated with a significantly increased risk of hereditary breast and ovarian cancer. Howev

Updated on:February 01,2024

Researchers find superantigen mutant can trigger immune response in ovarian cancer cells

by Liu Jia,Chinese Academy of SciencesThe transwell co-culture models of transcriptome experiment. Credit:International Journal of Molecular Sciences(2023). DOI: 10.3390/ijms24141179

Updated on: January 30,2024

Researchers find superantigen mutant can trigger immune response in ovarian cancer cells

by Liu Jia,Chinese Academy of SciencesThe transwell co-culture models of transcriptome experiment. Credit:International Journal of Molecular Sciences(2023). DOI: 10.3390/ijms24141179

Updated on:January 30,2024

COVID reforms in cancer care and research could have long-term benefits

by King's College LondonCredit: Unsplash/CC0 Public DomainA new review led by Professor James Spicer considers the reforms in cancer care and research made due to the pandemic, arguing that s

Updated on: January 29,2024

COVID reforms in cancer care and research could have long-term benefits

by King's College LondonCredit: Unsplash/CC0 Public DomainA new review led by Professor James Spicer considers the reforms in cancer care and research made due to the pandemic, arguing that s

Updated on:January 29,2024