FDA approves Abecma for relapsed, refractory multiple myeloma

by Lori SolomonThe U.S. Food and Drug Administration has approved Abecma (idecabtagene vicleucel) as a personalized CAR T-cell therapy for triple-class exposed relapsed or refractory multiple myeloma.

Updated on: April 28,2024

FDA approves Abecma for relapsed, refractory multiple myeloma

by Lori SolomonThe U.S. Food and Drug Administration has approved Abecma (idecabtagene vicleucel) as a personalized CAR T-cell therapy for triple-class exposed relapsed or refractory multiple myeloma.

Updated on:April 28,2024

Immune cells trained to hunt tumors after scientists plant synthetic 'flags' on cancer

Updated on: June 15,2025

Immune cells trained to hunt tumors after scientists plant synthetic 'flags' on cancer

Updated on:June 15,2025

CAR-T Therapy Under Scrutiny: The Emerging Risk of Secondary Malignant Tumors

CAR-T therapy has long been an effective treatment for hematological cancers such as leukemia and lymphoma. However, some patients have developed secondary malignant tumors after undergoing CAR-T ......

Updated on: May 29,2024

CAR-T Therapy Under Scrutiny: The Emerging Risk of Secondary Malignant Tumors

CAR-T therapy has long been an effective treatment for hematological cancers such as leukemia and lymphoma. However, some patients have developed secondary malignant tumors after undergoing CAR-T ......

Updated on:May 29,2024

New health mapping study pinpoints cancer risk factors at local level

byQueensland University of TechnologyThe maps show areas where unhealthy behaviors are more (marked in red) or less (in blue) common than the national average. The deeper the shade, the greater

Updated on: December 28,2023

New health mapping study pinpoints cancer risk factors at local level

byQueensland University of TechnologyThe maps show areas where unhealthy behaviors are more (marked in red) or less (in blue) common than the national average. The deeper the shade, the greater

Updated on:December 28,2023

Erectile dysfunction medications may increase risk of death when combined with common chest pain medication

by American College of CardiologyCredit: Unsplash/CC0 Public DomainPhosphodiesterase type 5 inhibitors (PDE5i)—an erectile dysfunction drug sold under the names Viagra, Levitra, Cialis, and other

Updated on: March 25,2024

Erectile dysfunction medications may increase risk of death when combined with common chest pain medication

by American College of CardiologyCredit: Unsplash/CC0 Public DomainPhosphodiesterase type 5 inhibitors (PDE5i)—an erectile dysfunction drug sold under the names Viagra, Levitra, Cialis, and other

Updated on:March 25,2024

Tiny, implantable therapeutic sponge device helps kill cancer in mice

by Wayne Lewis,University of California, Los AngelesThe SymphNode device (left), contains nanoparticles (red dots) that release a drug that blocks the activity of regulatory T cells (green), whi

Updated on: January 08,2024

Tiny, implantable therapeutic sponge device helps kill cancer in mice

by Wayne Lewis,University of California, Los AngelesThe SymphNode device (left), contains nanoparticles (red dots) that release a drug that blocks the activity of regulatory T cells (green), whi

Updated on:January 08,2024

Colon cancer screenings are more effective than previously understood: Study

by Peter Dizikes,Massachusetts Institute of TechnologyCredit: Unsplash/CC0 Public DomainScreening for colon cancer reduces cancer rates by substantially more than previous analyses of randomized

Updated on: December 30,2023

Colon cancer screenings are more effective than previously understood: Study

by Peter Dizikes,Massachusetts Institute of TechnologyCredit: Unsplash/CC0 Public DomainScreening for colon cancer reduces cancer rates by substantially more than previous analyses of randomized

Updated on:December 30,2023

Genetic discovery could improve treatment of colorectal cancer

by Rémi Carlier,Ecole Polytechnique Federale de LausannePOU5F1B differs from OCT4. a Representative immunofluorescence–confocal microscopy of POU5F1B-HA overexpressing SW480 cells, with DAPI in

Updated on: December 25,2023

Genetic discovery could improve treatment of colorectal cancer

by Rémi Carlier,Ecole Polytechnique Federale de LausannePOU5F1B differs from OCT4. a Representative immunofluorescence–confocal microscopy of POU5F1B-HA overexpressing SW480 cells, with DAPI in

Updated on:December 25,2023

Researchers uncover on/off switch for breast cancer metastasis

by Rebecca McClellan,Stanford UniversitySongnan Wang (left) and Lingyin Li (right) found that a protein called ENPP1 acts as an on/off switch for breast cancer metastases. High protein levels le

Updated on: December 28,2023

Researchers uncover on/off switch for breast cancer metastasis

by Rebecca McClellan,Stanford UniversitySongnan Wang (left) and Lingyin Li (right) found that a protein called ENPP1 acts as an on/off switch for breast cancer metastases. High protein levels le

Updated on:December 28,2023

Delivering oxygen to tumors may be key in overcoming radiation therapy resistance

by National Institute of Biomedical Imaging and BioengineeringOxygen in tumors is necessary for radiotherapy to effectively treat cancer, but when tumors are hypoxic, this method can fail. A new strat

Updated on: January 10,2024

Delivering oxygen to tumors may be key in overcoming radiation therapy resistance

by National Institute of Biomedical Imaging and BioengineeringOxygen in tumors is necessary for radiotherapy to effectively treat cancer, but when tumors are hypoxic, this method can fail. A new strat

Updated on:January 10,2024

Antibody-based therapy eliminates circulating tumor cells in mouse models of breast and pancreatic cancer

by Katie Marquedant,Massachusetts General Hospital(A) Schema for the mouse models of neoadjuvant placebo or 23C6 treatment. (B) Tumor volume measurements of 4T1 orthotopic mammary gland tumors i

Updated on: December 25,2023

Antibody-based therapy eliminates circulating tumor cells in mouse models of breast and pancreatic cancer

by Katie Marquedant,Massachusetts General Hospital(A) Schema for the mouse models of neoadjuvant placebo or 23C6 treatment. (B) Tumor volume measurements of 4T1 orthotopic mammary gland tumors i

Updated on:December 25,2023

p53 mutations in 10,000 cancer patients shed new light on gene's function

by Molly Chiu,Baylor College of MedicineKiller T cells surround a cancer cell. Credit: NIHOne of the most extensively studied genes in cancer, TP53 is well known for its role as a tumor suppress

Updated on: March 14,2024

p53 mutations in 10,000 cancer patients shed new light on gene's function

by Molly Chiu,Baylor College of MedicineKiller T cells surround a cancer cell. Credit: NIHOne of the most extensively studied genes in cancer, TP53 is well known for its role as a tumor suppress

Updated on:March 14,2024