Evaluation of ruxolitinib, a JAK inhibitor, in multiple myeloma

by Impact Journals LLCRuxolitinib exerts its anti-myeloma effects through several mechanisms. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28547A new research perspective titled &quot

Updated on: May 07,2024

Evaluation of ruxolitinib, a JAK inhibitor, in multiple myeloma

by Impact Journals LLCRuxolitinib exerts its anti-myeloma effects through several mechanisms. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28547A new research perspective titled &quot

Updated on:May 07,2024

Preventing 'identity theft' in prostate cancer cells re-sensitizes them to therapy

byUT Southwestern Medical CenterJAK–STAT signaling is required for Enz resistance in TP53/RB1-deficient mCRPC.a, Heat map representing the significantly changed signaling pathways in LNCaP

Updated on: December 22,2023

Preventing 'identity theft' in prostate cancer cells re-sensitizes them to therapy

byUT Southwestern Medical CenterJAK–STAT signaling is required for Enz resistance in TP53/RB1-deficient mCRPC.a, Heat map representing the significantly changed signaling pathways in LNCaP

Updated on:December 22,2023

Black men found to have greater microvascular dysfunction than white men after prostate cancer diagnosis

byAmerican Physiological SocietyCredit: Pixabay/CC0 Public DomainMicrovascular function is lower is Black men following a recent diagnosis of prostate cancer, compared to white men, according to

Updated on: April 30,2024

Black men found to have greater microvascular dysfunction than white men after prostate cancer diagnosis

byAmerican Physiological SocietyCredit: Pixabay/CC0 Public DomainMicrovascular function is lower is Black men following a recent diagnosis of prostate cancer, compared to white men, according to

Updated on:April 30,2024

National quality improvement initiative successfully helps address pandemic-related cancer screening deficits

byAmerican College of SurgeonsMean Monthly Screening Test Volumes in April Through November. 2021 April and May 2021 is the preintervention period. Vertical dotted line indicates the start of th

Updated on: December 23,2023

National quality improvement initiative successfully helps address pandemic-related cancer screening deficits

byAmerican College of SurgeonsMean Monthly Screening Test Volumes in April Through November. 2021 April and May 2021 is the preintervention period. Vertical dotted line indicates the start of th

Updated on:December 23,2023

Researchers develop gel to deliver cancer drugs for solid tumors

byMass General BrighamCredit: Pixabay/CC0 Public DomainIntratumoral therapy—in which cancer drugs are injected directly into tumors—is a promising treatment option for solid cancers but has show

Updated on: January 03,2024

Researchers develop gel to deliver cancer drugs for solid tumors

byMass General BrighamCredit: Pixabay/CC0 Public DomainIntratumoral therapy—in which cancer drugs are injected directly into tumors—is a promising treatment option for solid cancers but has show

Updated on:January 03,2024

Exploring artificial general intelligence for radiation oncology

by KeAi Communications Co.Large Multimodal Foundation Models For Radiation Oncology. Credit: Chenbin LiuAn estimated 600,000 people in the United States succumb to cancer every year. Beyond surgery, c

Updated on: December 28,2023

Exploring artificial general intelligence for radiation oncology

by KeAi Communications Co.Large Multimodal Foundation Models For Radiation Oncology. Credit: Chenbin LiuAn estimated 600,000 people in the United States succumb to cancer every year. Beyond surgery, c

Updated on:December 28,2023

Most incidentally found adrenal tumors are nonfunctioning, regardless of patient age

by American College of PhysiciansCredit: Pixabay/CC0 Public DomainA cross-sectional study of more than 25,000 adults has found that with increased screening, the prevalence of adrenal tumors in an uns

Updated on: December 20,2023

Most incidentally found adrenal tumors are nonfunctioning, regardless of patient age

by American College of PhysiciansCredit: Pixabay/CC0 Public DomainA cross-sectional study of more than 25,000 adults has found that with increased screening, the prevalence of adrenal tumors in an uns

Updated on:December 20,2023

Unique insights into differences between primary and metastatic cancer by large-scale DNA data analyses

by Hartwig Medical FoundationInference of HLA-I tumor status with LILAC. a, Representation of the six immune escape pathways considered in the present study alongside their associated genes (adapted f

Updated on: January 07,2024

Unique insights into differences between primary and metastatic cancer by large-scale DNA data analyses

by Hartwig Medical FoundationInference of HLA-I tumor status with LILAC. a, Representation of the six immune escape pathways considered in the present study alongside their associated genes (adapted f

Updated on:January 07,2024

Researchers develop new open-source method to improve decoding of single-cell data

by Ian Demsky,Memorial Sloan Kettering Cancer CenterSpectra uses gene sets and cell types to guide gene program discovery from scRNA-seq data.a, As input, Spectra receives a gene expressio

Updated on: June 11,2024

Researchers develop new open-source method to improve decoding of single-cell data

by Ian Demsky,Memorial Sloan Kettering Cancer CenterSpectra uses gene sets and cell types to guide gene program discovery from scRNA-seq data.a, As input, Spectra receives a gene expressio

Updated on:June 11,2024

Researchers find a common immune system mechanism between pregnancy and cancer

by Nicole Fawcett,University of MichiganCredit:Cell(2024). DOI: 10.1016/j.cell.2024.06.012To understand why some cancers successfully circumvent the immune system to grow unchecked,

Updated on: July 09,2024

Researchers find a common immune system mechanism between pregnancy and cancer

by Nicole Fawcett,University of MichiganCredit:Cell(2024). DOI: 10.1016/j.cell.2024.06.012To understand why some cancers successfully circumvent the immune system to grow unchecked,

Updated on:July 09,2024

Incurable but not hopeless: How hope shapes patients' awareness of their advanced cancer prognosis

by Jean Mathews and Michael Brundage,The ConversationCredit: Unsplash/CC0 Public DomainHope is defined as the expectation of achieving a future good. Patients with cancer, whether it is curable

Updated on: March 30,2024

Incurable but not hopeless: How hope shapes patients' awareness of their advanced cancer prognosis

by Jean Mathews and Michael Brundage,The ConversationCredit: Unsplash/CC0 Public DomainHope is defined as the expectation of achieving a future good. Patients with cancer, whether it is curable

Updated on:March 30,2024

Killer T cells get better with age, study finds

by Claudia Ehrlich, Universität des SaarlandesDr. Annette Lis (R) and Dorina Zöphel (L) of Saarland University are studying how the activity of killer cells changes as the cells age. Credit: Oliver Di

Updated on: January 23,2024

Killer T cells get better with age, study finds

by Claudia Ehrlich, Universität des SaarlandesDr. Annette Lis (R) and Dorina Zöphel (L) of Saarland University are studying how the activity of killer cells changes as the cells age. Credit: Oliver Di

Updated on:January 23,2024