Novel therapeutic targets discovered for triple-negative breast cancer

by Melissa Rohman,Northwestern UniversityThe signature of TRIM21low/CD73highis associated with unfavorable immune response. (A) Proteomic data from CPTAC identified that the expression of

Updated on: December 21,2023 13

Novel therapeutic targets discovered for triple-negative breast cancer

by Melissa Rohman,Northwestern UniversityThe signature of TRIM21low/CD73highis associated with unfavorable immune response. (A) Proteomic data from CPTAC identified that the expression of

Updated on:December 21,2023 13

Tracking genes to fight breast cancer

byLeiden UniversityMicroscope image of moving breast cancer cells leaving a track. Koedoot: "We switched of certain proteins and then looked to see if the pathways changed." Credit: Es

Updated on: December 20,2023 21

Tracking genes to fight breast cancer

byLeiden UniversityMicroscope image of moving breast cancer cells leaving a track. Koedoot: "We switched of certain proteins and then looked to see if the pathways changed." Credit: Es

Updated on:December 20,2023 21

FAM3C encapsulated in circulating tumor-derived extracellular vesicles promotes distant growth in lung cancers

byNational University of SingaporeTumor-derived EVs containing FAM3C trigger aggressiveness of lung carcinoma cells in vivo. (A) Tail vein injection of A549 lung carcinoma cells in mouse model a

Updated on: December 19,2023 6

FAM3C encapsulated in circulating tumor-derived extracellular vesicles promotes distant growth in lung cancers

byNational University of SingaporeTumor-derived EVs containing FAM3C trigger aggressiveness of lung carcinoma cells in vivo. (A) Tail vein injection of A549 lung carcinoma cells in mouse model a

Updated on:December 19,2023 6

CYNK-101 Plus Avelumab Mediates ADCC Activity in Select PD-L1+ Solid Tumors

November 13, 2022Gina MauroCYNK-101 demonstrated synergistic activity when used in combination with avelumab through antibody-dependent cellular cytotoxicity against PD-L1–positive non–small cell lung

Updated on: October 17,2023 129

CYNK-101 Plus Avelumab Mediates ADCC Activity in Select PD-L1+ Solid Tumors

November 13, 2022Gina MauroCYNK-101 demonstrated synergistic activity when used in combination with avelumab through antibody-dependent cellular cytotoxicity against PD-L1–positive non–small cell lung

Updated on:October 17,2023 129

Targeted drug tagrisso could be advance against lung cancer

Updated on: December 19,2023 8

Targeted drug tagrisso could be advance against lung cancer

Updated on:December 19,2023 8

EMA Accepts Marketing Application for Odronextamab in R/R DLBCL or Follicular Lymphoma

August 17, 2023Chris RyanThe European Medicines Agency has accepted a marketing authorization application seeking the approval of odronextamab for the treatment of adult patients with relapsed/refract

Updated on: October 12,2023 6

EMA Accepts Marketing Application for Odronextamab in R/R DLBCL or Follicular Lymphoma

August 17, 2023Chris RyanThe European Medicines Agency has accepted a marketing authorization application seeking the approval of odronextamab for the treatment of adult patients with relapsed/refract

Updated on:October 12,2023 6

Seeking leukemia's Achilles heel

byAmerican Society for Biochemistry and Molecular BiologyGraphical abstract. Credit:Molecular & Cellular Proteomics(2023). DOI: 10.1016/j.mcpro.2023.100503A team of researchers h

Updated on: December 17,2023 10

Seeking leukemia's Achilles heel

byAmerican Society for Biochemistry and Molecular BiologyGraphical abstract. Credit:Molecular & Cellular Proteomics(2023). DOI: 10.1016/j.mcpro.2023.100503A team of researchers h

Updated on:December 17,2023 10

Interrupting endocrine therapy to pursue pregnancy doesn't lead to worse short-term breast cancer recurrence rates

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainBreast cancer patients who paused their endocrine therapy to try to get pregnant experienced short-term rates of breas

Updated on: January 08,2024 10

Interrupting endocrine therapy to pursue pregnancy doesn't lead to worse short-term breast cancer recurrence rates

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainBreast cancer patients who paused their endocrine therapy to try to get pregnant experienced short-term rates of breas

Updated on:January 08,2024 10

U.S. incidence of thyroid cancer plateaued in 2009

(HealthDay)—From 2009 to 2016, the incidence of thyroid cancer reached a plateau and possibly started to decline, according to a research letter published in the Dec. 24/31 issue of theJournal o

Updated on: December 20,2023 15

U.S. incidence of thyroid cancer plateaued in 2009

(HealthDay)—From 2009 to 2016, the incidence of thyroid cancer reached a plateau and possibly started to decline, according to a research letter published in the Dec. 24/31 issue of theJournal o

Updated on:December 20,2023 15

Discovery explains cancer chemotherapy resistance, offers solution

byCornell UniversityGraphical abstract. Credit:Molecular Cell(2022). DOI: 10.1016/j.molcel.2022.08.028Researchers have uncovered a novel pathway that explains how cancer cells become

Updated on: December 21,2023 4

Discovery explains cancer chemotherapy resistance, offers solution

byCornell UniversityGraphical abstract. Credit:Molecular Cell(2022). DOI: 10.1016/j.molcel.2022.08.028Researchers have uncovered a novel pathway that explains how cancer cells become

Updated on:December 21,2023 4

Patient's own immune cells effective as living medicine for melanoma

byNetherlands Cancer InstitutePreparing tumor-infiltrating lymphocyte therapy for melanoma patients in the lab. Credit: NKIA patient's own immune cells, multiplied into an army of billions o

Updated on: December 19,2023 10

Patient's own immune cells effective as living medicine for melanoma

byNetherlands Cancer InstitutePreparing tumor-infiltrating lymphocyte therapy for melanoma patients in the lab. Credit: NKIA patient's own immune cells, multiplied into an army of billions o

Updated on:December 19,2023 10

With Urological Cancer and COVID-19 Undergoing Elective Surgery at Higher Risk for Mortality

July 10, 2021Kristi RosaPatients with a urological cancer who were also infected with COVID-19 and undergoing elective surgery for their disease, were found to have a significantly higher likelihood o

Updated on: October 24,2023 60

With Urological Cancer and COVID-19 Undergoing Elective Surgery at Higher Risk for Mortality

July 10, 2021Kristi RosaPatients with a urological cancer who were also infected with COVID-19 and undergoing elective surgery for their disease, were found to have a significantly higher likelihood o

Updated on:October 24,2023 60