Next-generation trial shows five-drug combo can keep 'ultra-high-risk' bone marrow cancer at bay

byInstitute of Cancer ResearchImmunofluorescent image of autophagosomes in multiple myeloma cells. Credit: Institute of Cancer ResearchCombining five existing drugs can keep a highly aggressive

Updated on: January 15,2024 19

Next-generation trial shows five-drug combo can keep 'ultra-high-risk' bone marrow cancer at bay

byInstitute of Cancer ResearchImmunofluorescent image of autophagosomes in multiple myeloma cells. Credit: Institute of Cancer ResearchCombining five existing drugs can keep a highly aggressive

Updated on:January 15,2024 19

Hunting brain cancer cells: Neuronal and tumorigenic boundaries of glioblastoma plasticity

byFlinders UniversityGlioblastoma tumor cells express aberrant neuronal signatures and differentiate along a neurodevelopmental trajectory. (A) Healthy neuronal cells transform to a malignant ph

Updated on: January 15,2024 17

Hunting brain cancer cells: Neuronal and tumorigenic boundaries of glioblastoma plasticity

byFlinders UniversityGlioblastoma tumor cells express aberrant neuronal signatures and differentiate along a neurodevelopmental trajectory. (A) Healthy neuronal cells transform to a malignant ph

Updated on:January 15,2024 17

A step forward in the struggle against neuroblastoma, a type of childhood cancer

by University of SevilleCredit: CC0 Public DomainA group of researchers from the University of Seville and the Seville Biomedicine Institute (Instituto de Biomedicina de Sevilla—IBiS) has publish

Updated on: March 09,2024 16

A step forward in the struggle against neuroblastoma, a type of childhood cancer

by University of SevilleCredit: CC0 Public DomainA group of researchers from the University of Seville and the Seville Biomedicine Institute (Instituto de Biomedicina de Sevilla—IBiS) has publish

Updated on:March 09,2024 16

Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on: August 26,2024 0

Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on:August 26,2024 0

Blood test spots early pancreatic cancers with 97% accuracy

by Dennis ThompsonA blood test appears capable of detecting early-stage pancreatic cancers with up to 97% accuracy, a new study reports.The test looks for eight small RNA particles and eight larger DN

Updated on: April 28,2024 0

Blood test spots early pancreatic cancers with 97% accuracy

by Dennis ThompsonA blood test appears capable of detecting early-stage pancreatic cancers with up to 97% accuracy, a new study reports.The test looks for eight small RNA particles and eight larger DN

Updated on:April 28,2024 0

Researchers identify mechanism that allow ketamine to act both fast and slow

by Northwestern UniversityMultiple doses of ketamine do not increase the activity of immature neurons. Credit:Cellular and Molecular Life Sciences(2024). DOI: 10.1007/s00018-024-05121

Updated on: May 16,2024 6

Researchers identify mechanism that allow ketamine to act both fast and slow

by Northwestern UniversityMultiple doses of ketamine do not increase the activity of immature neurons. Credit:Cellular and Molecular Life Sciences(2024). DOI: 10.1007/s00018-024-05121

Updated on:May 16,2024 6

Study suggests the possibility of combination therapy of SORA and FGF21 in hepatocellular carcinoma

by Higher Education PressFGF21 combined with SORA promotes apoptosis and inhibits proliferation of 7721‐Smad3 cells under anaerobic conditions. Credit: Ting Zhang, Huiling Shi, Shihui Zhang, Qin Zhu,

Updated on: May 16,2024 7

Study suggests the possibility of combination therapy of SORA and FGF21 in hepatocellular carcinoma

by Higher Education PressFGF21 combined with SORA promotes apoptosis and inhibits proliferation of 7721‐Smad3 cells under anaerobic conditions. Credit: Ting Zhang, Huiling Shi, Shihui Zhang, Qin Zhu,

Updated on:May 16,2024 7

Convection-enhanced delivery of topotecan active in glioblastoma

by Elana GotkineA subcutaneously implanted, catheter-pump system capable of chronic convection-enhanced delivery (CED) of topotecan is well tolerated and active for patients with recurrent glioblastom

Updated on: January 30,2024 20

Convection-enhanced delivery of topotecan active in glioblastoma

by Elana GotkineA subcutaneously implanted, catheter-pump system capable of chronic convection-enhanced delivery (CED) of topotecan is well tolerated and active for patients with recurrent glioblastom

Updated on:January 30,2024 20

Time of day matters when it comes to cancer diagnosis and treatment, says metastasis study

byCell PressCredit: Unsplash/CC0 Public DomainYour circadian rhythm doesn't just govern your sleeping schedule; it can also impact cancer development, diagnosis, and treatment. In a review p

Updated on: January 23,2024 12

Time of day matters when it comes to cancer diagnosis and treatment, says metastasis study

byCell PressCredit: Unsplash/CC0 Public DomainYour circadian rhythm doesn't just govern your sleeping schedule; it can also impact cancer development, diagnosis, and treatment. In a review p

Updated on:January 23,2024 12

Study suggests new strategies against bone metastases from prostate cancer

by Garth Sundem,CU Anschutz Medical CampusWhen prostate cancer spreads, it most often spreads to bone. And while the 5-year survival rate for prostate cancer that has not spread is nearly 100 pe

Updated on: June 01,2024 5

Study suggests new strategies against bone metastases from prostate cancer

by Garth Sundem,CU Anschutz Medical CampusWhen prostate cancer spreads, it most often spreads to bone. And while the 5-year survival rate for prostate cancer that has not spread is nearly 100 pe

Updated on:June 01,2024 5

Uptake of HIV prevention medication doubles with mix of digital health interventions, study finds

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainA UCLA Health-led study found a combination of interventions of one-on-one telehealth coaching, peer support forums, and a

Updated on: May 16,2024 7

Uptake of HIV prevention medication doubles with mix of digital health interventions, study finds

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainA UCLA Health-led study found a combination of interventions of one-on-one telehealth coaching, peer support forums, and a

Updated on:May 16,2024 7

Microbubbles could help bowel cancer patients avoid life-changing surgeries

byUniversity of Strathclyde, Glasgow(a) KPN [13,14] or WT organoids were generated from KPN or C57BL6/J mice, respectively, and were injected into the hind leg of C57BL6/J mice. Animals injected

Updated on: January 08,2024 10

Microbubbles could help bowel cancer patients avoid life-changing surgeries

byUniversity of Strathclyde, Glasgow(a) KPN [13,14] or WT organoids were generated from KPN or C57BL6/J mice, respectively, and were injected into the hind leg of C57BL6/J mice. Animals injected

Updated on:January 08,2024 10