First-in-human clinical trial of CAR T cell therapy with new binding mechanism shows promising early responses

by Perelman School of Medicine at the University of PennsylvaniaSafety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with

Updated on: January 26,2024

First-in-human clinical trial of CAR T cell therapy with new binding mechanism shows promising early responses

by Perelman School of Medicine at the University of PennsylvaniaSafety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with

Updated on:January 26,2024

Air pollution from fossil fuel use accounts for over 5 million extra deaths a year, new modeling study finds

by British Medical JournalCredit: CC0 Public DomainAir pollution from using fossil fuels in industry, power generation, and transportation accounts for 5.1 million extra deaths a year worldwide,

Updated on: May 23,2024

Air pollution from fossil fuel use accounts for over 5 million extra deaths a year, new modeling study finds

by British Medical JournalCredit: CC0 Public DomainAir pollution from using fossil fuels in industry, power generation, and transportation accounts for 5.1 million extra deaths a year worldwide,

Updated on:May 23,2024

Machine learning to identify cancer type-specific driver mutations for the development of new drug targets

by Pohang University of Science & Technology (POSTECH)Credit: POSTECHAccording to Statistics Korea, cancer is the top cause of death in 2021, accounting for 26% of deaths. Most cancer patients mis

Updated on: December 25,2023

Machine learning to identify cancer type-specific driver mutations for the development of new drug targets

by Pohang University of Science & Technology (POSTECH)Credit: POSTECHAccording to Statistics Korea, cancer is the top cause of death in 2021, accounting for 26% of deaths. Most cancer patients mis

Updated on:December 25,2023

Treat cancer with cold plasma? Aerospace engineer helps bring first clinical trial

by Kayla Wiles,Purdue UniversityPurdue aerospace engineer Alexey Shashurin assisted in the development of the Canady Helios Cold Plasma System and Scalpel, which has been approved by the FDA for

Updated on: May 11,2024

Treat cancer with cold plasma? Aerospace engineer helps bring first clinical trial

by Kayla Wiles,Purdue UniversityPurdue aerospace engineer Alexey Shashurin assisted in the development of the Canady Helios Cold Plasma System and Scalpel, which has been approved by the FDA for

Updated on:May 11,2024

Why are more young people like Kate Middleton being diagnosed with cancer?

by Cynthia McCormick Hibbert,Northeastern UniversityCredit: Pixabay/CC0 Public DomainPrincess Catherine's announcement Friday that she has been diagnosed with cancer at age 42 makes her part

Updated on: March 30,2024

Why are more young people like Kate Middleton being diagnosed with cancer?

by Cynthia McCormick Hibbert,Northeastern UniversityCredit: Pixabay/CC0 Public DomainPrincess Catherine's announcement Friday that she has been diagnosed with cancer at age 42 makes her part

Updated on:March 30,2024

​ Vigilant monitoring is needed to manage cardiac risks in patients using antipsychotics, doctors say

by ElsevierCredit: Unsplash/CC0 Public DomainThe use of the antipsychotic drugs quetiapine and haloperidol is associated with an increased risk of ventricular arrhythmias and sudden cardiac death

Updated on: May 06,2024

​ Vigilant monitoring is needed to manage cardiac risks in patients using antipsychotics, doctors say

by ElsevierCredit: Unsplash/CC0 Public DomainThe use of the antipsychotic drugs quetiapine and haloperidol is associated with an increased risk of ventricular arrhythmias and sudden cardiac death

Updated on:May 06,2024

Study shows potential for new radiopharmaceutical cancer treatment

by Elizabeth Chapin,University of KentuckyGastrin- releasing peptide receptor (GRPR) immunoreactivity in uterine cervix cancer. Hematoxylin and eosin (H&E) staining of uterine cervix cancer

Updated on: February 20,2024

Study shows potential for new radiopharmaceutical cancer treatment

by Elizabeth Chapin,University of KentuckyGastrin- releasing peptide receptor (GRPR) immunoreactivity in uterine cervix cancer. Hematoxylin and eosin (H&E) staining of uterine cervix cancer

Updated on:February 20,2024

A partnership to tackle childhood cancers in developing countries

by St. Jude Children's Research HospitalCancer cell during cell division. Credit: National Institutes of HealthThe International Atomic Energy Agency (IAEA) and St. Jude Children's Resear

Updated on: April 23,2024

A partnership to tackle childhood cancers in developing countries

by St. Jude Children's Research HospitalCancer cell during cell division. Credit: National Institutes of HealthThe International Atomic Energy Agency (IAEA) and St. Jude Children's Resear

Updated on:April 23,2024

Study provides new insights for ways to use cell metabolism to treat cancer

by Katie Pence,University of Cincinnati Academic Health CenterResearchers at the University of Cincinnati (UC) College of Medicine have discovered that cell metabolism plays an important role in

Updated on: April 18,2024

Study provides new insights for ways to use cell metabolism to treat cancer

by Katie Pence,University of Cincinnati Academic Health CenterResearchers at the University of Cincinnati (UC) College of Medicine have discovered that cell metabolism plays an important role in

Updated on:April 18,2024

Thalidomide reveals path for targeting undruggable transcription factors for cancer treatment

by Tom Ulrich,Broad Institute of MIT and HarvardCredit: Susanna M. Hamilton, Broad CommunicationsThalidomide, a morning-sickness drug recalled in the 1960s because it caused devastating birth de

Updated on: March 06,2024

Thalidomide reveals path for targeting undruggable transcription factors for cancer treatment

by Tom Ulrich,Broad Institute of MIT and HarvardCredit: Susanna M. Hamilton, Broad CommunicationsThalidomide, a morning-sickness drug recalled in the 1960s because it caused devastating birth de

Updated on:March 06,2024

Delayed treatment effect predicting (DTEP) model found to enhance precision in immuno-oncology trial designs

by Science China PressAt the trial design stage, by inputting information on treatment stage, cancer type, and experimental and control arm regimens, investigators can utilize the nomogram or web

Updated on: March 30,2024

Delayed treatment effect predicting (DTEP) model found to enhance precision in immuno-oncology trial designs

by Science China PressAt the trial design stage, by inputting information on treatment stage, cancer type, and experimental and control arm regimens, investigators can utilize the nomogram or web

Updated on:March 30,2024

Trial finds adding immunotherapy to neoadjuvant chemoradiation may improve outcomes in esophageal cancer

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainA studypublishedinClinical Cancer Researchfound that in patients with unresectable, locally advanced

Updated on: November 30,2024

Trial finds adding immunotherapy to neoadjuvant chemoradiation may improve outcomes in esophageal cancer

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainA studypublishedinClinical Cancer Researchfound that in patients with unresectable, locally advanced

Updated on:November 30,2024