FDA Approves Two Cell-Based SCD Gene Therapies

February 2024The U.S. Food and Drug Administration (FDA) approved exagamglogene autotemcel (exa-cel) and lovotibeglogene autotemcel (lovo-cel) for the treatment of sickle cell disease (SCD) in patient

Updated on: February 18,2024

FDA Approves Two Cell-Based SCD Gene Therapies

February 2024The U.S. Food and Drug Administration (FDA) approved exagamglogene autotemcel (exa-cel) and lovotibeglogene autotemcel (lovo-cel) for the treatment of sickle cell disease (SCD) in patient

Updated on:February 18,2024

New therapy could help chronic myeloid leukemia patients live drug-free

by South Australian Health and Medical Research Institute (SAHMRI)Credit: AI-generated imageThe latest research from SAHMRI and the University of Adelaide has discovered a potential new therapy for ch

Updated on: January 13,2024

New therapy could help chronic myeloid leukemia patients live drug-free

by South Australian Health and Medical Research Institute (SAHMRI)Credit: AI-generated imageThe latest research from SAHMRI and the University of Adelaide has discovered a potential new therapy for ch

Updated on:January 13,2024

Researchers examine role of fluid flow in ovarian cancer progression

by Virginia TechAfter multiple rounds of fluid shear stress exposure, human cells in the study began to form tumor-like structures known as spheroids (pictured). Spheroids are indicative of aggre

Updated on: June 15,2024

Researchers examine role of fluid flow in ovarian cancer progression

by Virginia TechAfter multiple rounds of fluid shear stress exposure, human cells in the study began to form tumor-like structures known as spheroids (pictured). Spheroids are indicative of aggre

Updated on:June 15,2024

AI could improve diagnostic accuracy of breast dynamic contrast-enhanced magnetic resonance imaging

A deep learning (DL) system could improve the diagnostic accuracy of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of breast tissue for detecting breast cancer, according to a study p

Updated on: January 02,2024

AI could improve diagnostic accuracy of breast dynamic contrast-enhanced magnetic resonance imaging

A deep learning (DL) system could improve the diagnostic accuracy of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of breast tissue for detecting breast cancer, according to a study p

Updated on:January 02,2024

Study gives new insight into how cancer metastasizes to the brain

by The Wistar InstituteIFN signaling is activated in brain metastasis.a–cIFN signaling is activated in both human astrocytes and MDA231-BrM cells by coculture in vitro.N = 2 bio

Updated on: February 20,2024

Study gives new insight into how cancer metastasizes to the brain

by The Wistar InstituteIFN signaling is activated in brain metastasis.a–cIFN signaling is activated in both human astrocytes and MDA231-BrM cells by coculture in vitro.N = 2 bio

Updated on:February 20,2024

Breakthrough research makes cancer-fighting viral agent more effective

byAarhus University4-OI promotes VSVΔ51 infection and oncolysis. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-48422-xWhen a cancer cell doesn't respond to traditio

Updated on: July 08,2024

Breakthrough research makes cancer-fighting viral agent more effective

byAarhus University4-OI promotes VSVΔ51 infection and oncolysis. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-48422-xWhen a cancer cell doesn't respond to traditio

Updated on:July 08,2024

Immune system holds clues to patients with high-risk smoldering myeloma likely to benefit from treatment

byDana-Farber Cancer InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.10.017For many patients with a condition that often precedes multiple myeloma, e

Updated on: January 02,2024

Immune system holds clues to patients with high-risk smoldering myeloma likely to benefit from treatment

byDana-Farber Cancer InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.10.017For many patients with a condition that often precedes multiple myeloma, e

Updated on:January 02,2024

Noninvasive technology for the high-throughput characterization of cancer cells

byTokyo University of ScienceSchematic of a cell rotation movement in a rotating AC electric field for (a) conventional ROT and (b) newly developed cROT. In conventional ROT in (a), when AC volt

Updated on: January 02,2024

Noninvasive technology for the high-throughput characterization of cancer cells

byTokyo University of ScienceSchematic of a cell rotation movement in a rotating AC electric field for (a) conventional ROT and (b) newly developed cROT. In conventional ROT in (a), when AC volt

Updated on:January 02,2024

Toward a personalized approach to the study and treatment of bone cancers

by Lund UniversityPrimary acute myeloid leukemia cells preferentially home and engraft in MSOD-B hOss.a, Experimental scheme of AML patient sample transplantation. b, Representative histological

Updated on: February 20,2024

Toward a personalized approach to the study and treatment of bone cancers

by Lund UniversityPrimary acute myeloid leukemia cells preferentially home and engraft in MSOD-B hOss.a, Experimental scheme of AML patient sample transplantation. b, Representative histological

Updated on:February 20,2024

Researchers reveal role of PPDPF in development of mutant KRAS-driven pancreatic ductal adenocarcinoma

by Liu Jia,Chinese Academy of SciencesSchematic representation demonstrating the function of PPDPF in KRAS activation. Credit: Dr. XIE Dong's groupA recent study by Dr. Xie Dong's group

Updated on: February 20,2024

Researchers reveal role of PPDPF in development of mutant KRAS-driven pancreatic ductal adenocarcinoma

by Liu Jia,Chinese Academy of SciencesSchematic representation demonstrating the function of PPDPF in KRAS activation. Credit: Dr. XIE Dong's groupA recent study by Dr. Xie Dong's group

Updated on:February 20,2024

Promising new pancreatic cancer treatment moves forward

by Huntsman Cancer InstituteCredit: CC0 Public DomainEven among cancers, pancreatic cancer is an especially sinister form of disease. The one-year survival rate is extremely low, and treatment progres

Updated on: May 07,2024

Promising new pancreatic cancer treatment moves forward

by Huntsman Cancer InstituteCredit: CC0 Public DomainEven among cancers, pancreatic cancer is an especially sinister form of disease. The one-year survival rate is extremely low, and treatment progres

Updated on:May 07,2024

New delivery strategy may improve chemotherapy for acute myeloid leukemia

byWileyCNL augments the efficacy of cytarabine/venetoclax treatment in in vivo AML models. (A–C) Bioluminescence images (A), their quantification (B) and survival of MOLM-13 Luc-YFP bearing NRG

Updated on: January 11,2024

New delivery strategy may improve chemotherapy for acute myeloid leukemia

byWileyCNL augments the efficacy of cytarabine/venetoclax treatment in in vivo AML models. (A–C) Bioluminescence images (A), their quantification (B) and survival of MOLM-13 Luc-YFP bearing NRG

Updated on:January 11,2024