The X chromosome is silenced in some male cancers

by Cell PressGraphical abstract depicting the study’s workflow. Credit:Cell Systems/Sadagopan et al.Cancer cells acquire genetic anomalies that allow them to grow and proliferate unchecked.

Updated on: February 03,2024

The X chromosome is silenced in some male cancers

by Cell PressGraphical abstract depicting the study’s workflow. Credit:Cell Systems/Sadagopan et al.Cancer cells acquire genetic anomalies that allow them to grow and proliferate unchecked.

Updated on:February 03,2024

Chemotherapy before surgery helps patients with nose and sinus cancer avoid debilitating eye and bone removal

by ECOG-ACRIN Cancer Research GroupCredit: CC0 Public DomainResults from a clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) show a striking improvement for patients who received che

Updated on: September 28,2024

Chemotherapy before surgery helps patients with nose and sinus cancer avoid debilitating eye and bone removal

by ECOG-ACRIN Cancer Research GroupCredit: CC0 Public DomainResults from a clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) show a striking improvement for patients who received che

Updated on:September 28,2024

Subtypes of fibroblasts associated with skin cancer could lead to novel immunotherapies

byMedical University of ViennaSchematic summary of spatial distribution of distinct CAF subsets in human skin cancer. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-5390

Updated on: December 01,2024

Subtypes of fibroblasts associated with skin cancer could lead to novel immunotherapies

byMedical University of ViennaSchematic summary of spatial distribution of distinct CAF subsets in human skin cancer. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-5390

Updated on:December 01,2024

Study finds increased MDS/leukemia risks for survivors of common lymphoid neoplasms

by Elana GotkineSurvivors of common lymphoid neoplasms (LNs) have increased risks for therapy-related myelodysplastic syndrome/acute myeloid leukemia (tMDS/AML), although risks have been lower in more

Updated on: January 23,2024

Study finds increased MDS/leukemia risks for survivors of common lymphoid neoplasms

by Elana GotkineSurvivors of common lymphoid neoplasms (LNs) have increased risks for therapy-related myelodysplastic syndrome/acute myeloid leukemia (tMDS/AML), although risks have been lower in more

Updated on:January 23,2024

Blood cancers: Expert explains what you need to know

by Robin FosterBlood cancer is not a diagnosis anyone wants to receive, but understanding the different types of this disease and how best to catch them early is essential, one expert says.First, bloo

Updated on: November 10,2024

Blood cancers: Expert explains what you need to know

by Robin FosterBlood cancer is not a diagnosis anyone wants to receive, but understanding the different types of this disease and how best to catch them early is essential, one expert says.First, bloo

Updated on:November 10,2024

FDA Approves Two Cell-Based SCD Gene Therapies

February 2024The U.S. Food and Drug Administration (FDA) approved exagamglogene autotemcel (exa-cel) and lovotibeglogene autotemcel (lovo-cel) for the treatment of sickle cell disease (SCD) in patient

Updated on: February 18,2024

FDA Approves Two Cell-Based SCD Gene Therapies

February 2024The U.S. Food and Drug Administration (FDA) approved exagamglogene autotemcel (exa-cel) and lovotibeglogene autotemcel (lovo-cel) for the treatment of sickle cell disease (SCD) in patient

Updated on:February 18,2024

Research team develops novel strategy to suppress prostate cancer growth

by Aaron Nieto,Baylor College of MedicineProstate cancer cells. Credit: NIH Image GalleryFinding valuable therapeutic interventions for prostate cancer has long guided the research of Dr. Feng Y

Updated on: February 20,2024

Research team develops novel strategy to suppress prostate cancer growth

by Aaron Nieto,Baylor College of MedicineProstate cancer cells. Credit: NIH Image GalleryFinding valuable therapeutic interventions for prostate cancer has long guided the research of Dr. Feng Y

Updated on:February 20,2024

Tumor heterogeneity and immune-evasive environment in malignant lymphoma at single-cell resolution

byUniversity of TsukubaTranscriptomic profile of T follicular helper cell lymphoma (TFHL) samples. Credit:Leukemia(2023). DOI: 10.1038/s41375-023-02093-7Researchers at the University

Updated on: January 26,2024

Tumor heterogeneity and immune-evasive environment in malignant lymphoma at single-cell resolution

byUniversity of TsukubaTranscriptomic profile of T follicular helper cell lymphoma (TFHL) samples. Credit:Leukemia(2023). DOI: 10.1038/s41375-023-02093-7Researchers at the University

Updated on:January 26,2024

Scientists develop a rapid gene-editing screen to find effects of cancer mutations

by Massachusetts Institute of TechnologyDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHTumors can carry mutations in hundreds of different gen

Updated on: March 20,2024

Scientists develop a rapid gene-editing screen to find effects of cancer mutations

by Massachusetts Institute of TechnologyDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHTumors can carry mutations in hundreds of different gen

Updated on:March 20,2024

Treating the TOTAL patient: clinical trial reduces relapse

by St. Jude Children's Research HospitalSima Jeha, M.D., of the St. Jude Departments of Oncology and Global Pediatric Medicine, and Ching-Hon Pui, M.D., chair of the St. Jude Department of On

Updated on: April 10,2024

Treating the TOTAL patient: clinical trial reduces relapse

by St. Jude Children's Research HospitalSima Jeha, M.D., of the St. Jude Departments of Oncology and Global Pediatric Medicine, and Ching-Hon Pui, M.D., chair of the St. Jude Department of On

Updated on:April 10,2024

Research finds alternating estrogen and anti-estrogen therapies effective in treating metastatic breast cancer

by Dartmouth HealthCredit: Unsplash/CC0 Public DomainAdvanced or metastatic estrogen receptor-positive (ER+) breast cancer is commonly treated with drugs that block the estrogen receptor. However

Updated on: February 24,2024

Research finds alternating estrogen and anti-estrogen therapies effective in treating metastatic breast cancer

by Dartmouth HealthCredit: Unsplash/CC0 Public DomainAdvanced or metastatic estrogen receptor-positive (ER+) breast cancer is commonly treated with drugs that block the estrogen receptor. However

Updated on:February 24,2024

Novel PET radiotracer successfully detects multiple cancers, offers potential for new targeted radionuclide therapy

by Society of Nuclear Medicine and Molecular ImagingMaximum-intensity projection images of 18F-fluorodeoxyglucose (FDG), 68Ga-FAP-2286, and 68Ga-FAPI-46 PET/CT imaging in seven patients with different

Updated on: January 15,2024

Novel PET radiotracer successfully detects multiple cancers, offers potential for new targeted radionuclide therapy

by Society of Nuclear Medicine and Molecular ImagingMaximum-intensity projection images of 18F-fluorodeoxyglucose (FDG), 68Ga-FAP-2286, and 68Ga-FAPI-46 PET/CT imaging in seven patients with different

Updated on:January 15,2024