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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Capturing immunotherapy response in a blood drop

Capturing immunotherapy response in a blood drop

byJohns Hopkins University School of MedicineAn impressionist painting of a liquid biopsy. Credit: Valsamo Anagnostou x DALL-E, openAILiquid biopsies are blood tests that can serially measure ci

Capturing immunotherapy response in a blood drop

byJohns Hopkins University School of MedicineAn impressionist painting of a liquid biopsy. Credit: Valsamo Anagnostou x DALL-E, openAILiquid biopsies are blood tests that can serially measure ci
To improve a promising cancer drug, cut it in half

To improve a promising cancer drug, cut it in half

by Ian Haydon,University of Washington School of MedicineNeoleukin-2/15 can be split into two fragments that reconstitute its activity when combined. a, Splitting strategy for Neo-2/15. Structur

To improve a promising cancer drug, cut it in half

by Ian Haydon,University of Washington School of MedicineNeoleukin-2/15 can be split into two fragments that reconstitute its activity when combined. a, Splitting strategy for Neo-2/15. Structur
Mapping oesophageal cancer genes leads to new drug targets

Mapping oesophageal cancer genes leads to new drug targets

byCancer Research UK| News4 February 2019Mutations that cause oesophageal adenocarcinoma (OAC) have been mapped in unprecedented detail – unveiling that more than half could be targeted by

Mapping oesophageal cancer genes leads to new drug targets

byCancer Research UK| News4 February 2019Mutations that cause oesophageal adenocarcinoma (OAC) have been mapped in unprecedented detail – unveiling that more than half could be targeted by
Chinese medicine ingredients found to generate autophagic flux to suppress tumor progression in gastric cancer

Chinese medicine ingredients found to generate autophagic flux to suppress tumor progression in gastric cancer

byScience China PressActivation of Beclin-1 by piceatannol promotes autophagic flux in GC cells, and combined with everolimus, triggers autophagic death, ultimately inhibiting tumor progression,

Chinese medicine ingredients found to generate autophagic flux to suppress tumor progression in gastric cancer

byScience China PressActivation of Beclin-1 by piceatannol promotes autophagic flux in GC cells, and combined with everolimus, triggers autophagic death, ultimately inhibiting tumor progression,
Saliva test shows promise for earlier and easier detection of mouth and throat cancer

Saliva test shows promise for earlier and easier detection of mouth and throat cancer

byElsevierAcoustofluidic exosome isolation chip for salivary exosome isolation. The microfluidic channel is shown by red dye solution and the coin demonstrates the size of the chip. Two pairs of

Saliva test shows promise for earlier and easier detection of mouth and throat cancer

byElsevierAcoustofluidic exosome isolation chip for salivary exosome isolation. The microfluidic channel is shown by red dye solution and the coin demonstrates the size of the chip. Two pairs of
Survival rates high for children, teens with melanoma

Survival rates high for children, teens with melanoma

by Lori SolomonSurvival rates for children and adolescents with melanomas are high, according to a study published online Dec. 9 in theJournal of the American Academy of Dermatology.Mary-Ann El

Survival rates high for children, teens with melanoma

by Lori SolomonSurvival rates for children and adolescents with melanomas are high, according to a study published online Dec. 9 in theJournal of the American Academy of Dermatology.Mary-Ann El
Study identifies genetic cause for some brain tumors

Study identifies genetic cause for some brain tumors

Study identifies genetic cause for some brain tumorsby Olivia Dimmer,Northwestern UniversityMultiplex immunofluorescence staining and imaging using the COMET system platform on a human meningiom

Study identifies genetic cause for some brain tumors

Study identifies genetic cause for some brain tumorsby Olivia Dimmer,Northwestern UniversityMultiplex immunofluorescence staining and imaging using the COMET system platform on a human meningiom
Multicenter Review Supports TKI Use in Patients With mRCC and Bone Metastases

Multicenter Review Supports TKI Use in Patients With mRCC and Bone Metastases

September 20, 2022Megan HollaschAn analysis of patterns of care and outcomes for patients with metastatic renal cell carcinoma with bone metastases supported the role of TKIs as the standard of care.&

Multicenter Review Supports TKI Use in Patients With mRCC and Bone Metastases

September 20, 2022Megan HollaschAn analysis of patterns of care and outcomes for patients with metastatic renal cell carcinoma with bone metastases supported the role of TKIs as the standard of care.&
Cancer prevention experts provide top tips for reducing cancer risk

Cancer prevention experts provide top tips for reducing cancer risk

by Rutgers Cancer Institute of New JerseyCredit: Pixabay/CC0 Public DomainMany forms of cancer are preventable. Although risk factors such as age or genetics cannot be changed, other risk factors for

Cancer prevention experts provide top tips for reducing cancer risk

by Rutgers Cancer Institute of New JerseyCredit: Pixabay/CC0 Public DomainMany forms of cancer are preventable. Although risk factors such as age or genetics cannot be changed, other risk factors for
Olaparib and adavosertib work best when given sequentially for DNA-damage response mutations in advanced tumors

Olaparib and adavosertib work best when given sequentially for DNA-damage response mutations in advanced tumors

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainPatients with cancers that are driven by certain mutations occurring in response to DNA damage can be safe

Olaparib and adavosertib work best when given sequentially for DNA-damage response mutations in advanced tumors

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainPatients with cancers that are driven by certain mutations occurring in response to DNA damage can be safe
One-cycle cisplatin seems safe for high-risk early testicular cancer

One-cycle cisplatin seems safe for high-risk early testicular cancer

(HealthDay)—For high-risk stage 1 nonseminoma germ cell tumors of the testis (NSGCTT), one cycle of adjuvant bleomycin, etoposide (500 mg/m²), and cisplatin (BE500P) is safe, resulting in a two-year m

One-cycle cisplatin seems safe for high-risk early testicular cancer

(HealthDay)—For high-risk stage 1 nonseminoma germ cell tumors of the testis (NSGCTT), one cycle of adjuvant bleomycin, etoposide (500 mg/m²), and cisplatin (BE500P) is safe, resulting in a two-year m
Protective mutation shown to impair esophagus tumor growth

Protective mutation shown to impair esophagus tumor growth

byWellcome Trust Sanger InstituteDifferentiation and homeostasis in aged Notch1 mutant mouse tissue. a, YFPCreNotch1flox/floxmice were induced at high dose so mutant cells rapidly covered

Protective mutation shown to impair esophagus tumor growth

byWellcome Trust Sanger InstituteDifferentiation and homeostasis in aged Notch1 mutant mouse tissue. a, YFPCreNotch1flox/floxmice were induced at high dose so mutant cells rapidly covered