Scientists target glioma cancer stem cells, which could improve patient survival

by Dartmouth-Hitchcock Medical CenterThis photo illustrates the effect of secretion inhibitors on the growth of high-grade glial tumors in mice. The top row show tumors grown in the absence of se

Updated on: March 06,2024

Scientists target glioma cancer stem cells, which could improve patient survival

by Dartmouth-Hitchcock Medical CenterThis photo illustrates the effect of secretion inhibitors on the growth of high-grade glial tumors in mice. The top row show tumors grown in the absence of se

Updated on:March 06,2024

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

by Impact JournalsMechanisms of SCR resistance and characterization of the CD20 negative MCL cell lines 353. Credit: LeBlanc et al,Oncotarget(2022). DOI: 10.18632/oncotarget.28258A new res

Updated on: January 02,2024

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma

by Impact JournalsMechanisms of SCR resistance and characterization of the CD20 negative MCL cell lines 353. Credit: LeBlanc et al,Oncotarget(2022). DOI: 10.18632/oncotarget.28258A new res

Updated on:January 02,2024

Researchers identify protein that may protect the heart during certain cancer treatment regimens

by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterCirculating Hpx is elevated in mice treated with Dox. (A) Dox-induced chronic cardiomyopathy model in mice. i.p., intraperitoneally. (B

Updated on: February 18,2024

Researchers identify protein that may protect the heart during certain cancer treatment regimens

by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterCirculating Hpx is elevated in mice treated with Dox. (A) Dox-induced chronic cardiomyopathy model in mice. i.p., intraperitoneally. (B

Updated on:February 18,2024

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Updated on: August 03,2024

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Updated on:August 03,2024

Study finds patient messages help predict medication adherence

by Paul Govern,Vanderbilt UniversityCredit: CC0 Public DomainAround two-thirds of patients treated for breast cancer will have had hormone-sensitive tumors and, after their initial treatment, wi

Updated on: March 06,2024

Study finds patient messages help predict medication adherence

by Paul Govern,Vanderbilt UniversityCredit: CC0 Public DomainAround two-thirds of patients treated for breast cancer will have had hormone-sensitive tumors and, after their initial treatment, wi

Updated on:March 06,2024

Levonorgestrel IUD feasible for low-risk, early uterine cancer

(HealthDay)—A levonorgestrel-releasing intrauterine device (LNG-IUD) is effective in the majority of patients undergoing conservative treatment for low-risk endometrial cancer and complex atypical hyp

Updated on: March 24,2024

Levonorgestrel IUD feasible for low-risk, early uterine cancer

(HealthDay)—A levonorgestrel-releasing intrauterine device (LNG-IUD) is effective in the majority of patients undergoing conservative treatment for low-risk endometrial cancer and complex atypical hyp

Updated on:March 24,2024

Obesity as a risk factor for colorectal cancer underestimated so far, says study

byGerman Cancer Research CenterWeight Change Among Cases and Controls Within 12 Years Before Diagnosis/Interview Lower and upper hinges correspond to 25th and 75th quantile of weight changes, re

Updated on: January 16,2024

Obesity as a risk factor for colorectal cancer underestimated so far, says study

byGerman Cancer Research CenterWeight Change Among Cases and Controls Within 12 Years Before Diagnosis/Interview Lower and upper hinges correspond to 25th and 75th quantile of weight changes, re

Updated on:January 16,2024

Study finds providers use prostate cancer screening tests, even when they provide little value to patients

byWake Forest University Baptist Medical CenterChris Gillette, Ph.D., associate professor of PA Studies for Wake Forest University School of Medicine, collaborates with colleagues. Credit: Wake

Updated on: January 23,2024

Study finds providers use prostate cancer screening tests, even when they provide little value to patients

byWake Forest University Baptist Medical CenterChris Gillette, Ph.D., associate professor of PA Studies for Wake Forest University School of Medicine, collaborates with colleagues. Credit: Wake

Updated on:January 23,2024

Discovery of a gene that could be key for reducing breast cancer risk

by University of OtagoCharacterization of SULT1A1. a Genomic viewer (UCSC) of the SULT1A1 gene locus with copy number variants; deletion (red) and duplication (blue). b Dosage effect in breast tu

Updated on: January 30,2024

Discovery of a gene that could be key for reducing breast cancer risk

by University of OtagoCharacterization of SULT1A1. a Genomic viewer (UCSC) of the SULT1A1 gene locus with copy number variants; deletion (red) and duplication (blue). b Dosage effect in breast tu

Updated on:January 30,2024

Expansion of cell-to-cell communication drives early development of pancreatic cancer, finds new research

by Ian Demsky,Memorial Sloan Kettering Cancer CenterA lens into epigenetic plasticity and its consequences on tumorigenesis. A genetically engineered mouse model enabled a longitudinal view of c

Updated on: February 18,2024

Expansion of cell-to-cell communication drives early development of pancreatic cancer, finds new research

by Ian Demsky,Memorial Sloan Kettering Cancer CenterA lens into epigenetic plasticity and its consequences on tumorigenesis. A genetically engineered mouse model enabled a longitudinal view of c

Updated on:February 18,2024

Researchers unveil experimental compound to block therapeutic target in blood cancer

by UNC Lineberger Comprehensive Cancer CenterBlossom Damania, PhD, Jason Wang and a team of UNC Lineberger researchers report in PNAS they have discovered a hyperactive cell signal that contribut

Updated on: June 15,2024

Researchers unveil experimental compound to block therapeutic target in blood cancer

by UNC Lineberger Comprehensive Cancer CenterBlossom Damania, PhD, Jason Wang and a team of UNC Lineberger researchers report in PNAS they have discovered a hyperactive cell signal that contribut

Updated on:June 15,2024

Cell competition may explain cancer relapses, research suggests

byUT Southwestern Medical CenterCredit:Cancer Discovery(2022). DOI: 10.1158/2159-8290.CD-22-0236A normal process called cell competition, in which healthy tissues eliminate unhealthy

Updated on: January 16,2024

Cell competition may explain cancer relapses, research suggests

byUT Southwestern Medical CenterCredit:Cancer Discovery(2022). DOI: 10.1158/2159-8290.CD-22-0236A normal process called cell competition, in which healthy tissues eliminate unhealthy

Updated on:January 16,2024