Pembrolizumab Monotherapy Displays Efficacy in Rare Sarcomas

The PD-1 inhibitor pembrolizumab (Keytruda) displayed activity with a manageable safety profile in patients with certain rare and ultra-raresarcoma histotypes, according to findings from the phase 2 A

Updated on: November 07,2023 6

Pembrolizumab Monotherapy Displays Efficacy in Rare Sarcomas

The PD-1 inhibitor pembrolizumab (Keytruda) displayed activity with a manageable safety profile in patients with certain rare and ultra-raresarcoma histotypes, according to findings from the phase 2 A

Updated on:November 07,2023 6

How does obesity cause cancer?

Overweight and obesity is the second biggest cause of cancer in the UK – causing more than 1 in 20 cancer cases.The risk is higher the more overweight you are and the longer you are overweight for.Kee

Updated on: December 19,2023 16

How does obesity cause cancer?

Overweight and obesity is the second biggest cause of cancer in the UK – causing more than 1 in 20 cancer cases.The risk is higher the more overweight you are and the longer you are overweight for.Kee

Updated on:December 19,2023 16

Skin cancer cells harness nerve cell gene to drill through and invade new tissues

byInstitute of Cancer ResearchMelanoma cell growing into a soft hydrogel. Credit: Professor Chris BakalMelanoma skin cancer cells harness a gene usually used by growing nerves to escape from the

Updated on: December 18,2023 22

Skin cancer cells harness nerve cell gene to drill through and invade new tissues

byInstitute of Cancer ResearchMelanoma cell growing into a soft hydrogel. Credit: Professor Chris BakalMelanoma skin cancer cells harness a gene usually used by growing nerves to escape from the

Updated on:December 18,2023 22

Localizing BRCA gene mutations to better treat ovarian cancer

byUniversity of GenevaDistribution of mutations in BRCA1 and BRCA2. A. Graphical summary of BRCA1 and BRCA2 mutations. Mutation plot was generated using cBioPortal MutationMapper tool. Black = n

Updated on: December 20,2023 10

Localizing BRCA gene mutations to better treat ovarian cancer

byUniversity of GenevaDistribution of mutations in BRCA1 and BRCA2. A. Graphical summary of BRCA1 and BRCA2 mutations. Mutation plot was generated using cBioPortal MutationMapper tool. Black = n

Updated on:December 20,2023 10

hematopoietic changes on colon cancer, unveiling therapeutic avenues

In a recent study published in theJournal of Experimental Medicine, researchers investigated whether bone marrow-derived cells with heterozygous loss of Dnmt3a (Dnmt3a+/Δ), the most common genet

Updated on: October 30,2023 29

hematopoietic changes on colon cancer, unveiling therapeutic avenues

In a recent study published in theJournal of Experimental Medicine, researchers investigated whether bone marrow-derived cells with heterozygous loss of Dnmt3a (Dnmt3a+/Δ), the most common genet

Updated on:October 30,2023 29

New optimism on myelodysplastic syndromes

by Sylvester Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainPhysician scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have publish

Updated on: December 22,2023 13

New optimism on myelodysplastic syndromes

by Sylvester Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainPhysician scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have publish

Updated on:December 22,2023 13

Results mixed for twice-daily APBI in early breast cancer

(HealthDay)—Accelerated partial breast irradiation (APBI) delivered twice per day over one week to the tumor bed is noninferior to whole breast irradiation for preventing ipsilateral breast tumor recu

Updated on: December 22,2023 11

Results mixed for twice-daily APBI in early breast cancer

(HealthDay)—Accelerated partial breast irradiation (APBI) delivered twice per day over one week to the tumor bed is noninferior to whole breast irradiation for preventing ipsilateral breast tumor recu

Updated on:December 22,2023 11

Scientists identify gene target to boost effectiveness of cancer immunotherapy

by Katie Marquedant,Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainImmune checkpoint inhibitors are important medications that boost the immune system's response against vari

Updated on: December 27,2023 9

Scientists identify gene target to boost effectiveness of cancer immunotherapy

by Katie Marquedant,Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainImmune checkpoint inhibitors are important medications that boost the immune system's response against vari

Updated on:December 27,2023 9

Study shows older age and smoking most important risk factors for developing any cancer

byAmerican Cancer SocietyCredit: Unsplash/CC0 Public DomainA new large study led by researchers at the American Cancer Society (ACS) shows older age and smoking are the two most important risk f

Updated on: December 18,2023 23

Study shows older age and smoking most important risk factors for developing any cancer

byAmerican Cancer SocietyCredit: Unsplash/CC0 Public DomainA new large study led by researchers at the American Cancer Society (ACS) shows older age and smoking are the two most important risk f

Updated on:December 18,2023 23

HER2+ early breast cancers where shorter-course trastuzumab could be an option

byEuropean Society for Medical OncologyCredit: European Society for Medical OncologyWomen with HER2-positive early breast cancer with small tumours have similar disease-free survival and lower r

Updated on: December 18,2023 17

HER2+ early breast cancers where shorter-course trastuzumab could be an option

byEuropean Society for Medical OncologyCredit: European Society for Medical OncologyWomen with HER2-positive early breast cancer with small tumours have similar disease-free survival and lower r

Updated on:December 18,2023 17

First test of anti-cancer agent PAC-1 in human clinical trials shows promise

by Diana Yates,University of Illinois at Urbana-ChampaignProcaspase-3 (PC-3) expressions in diverse tumor histologies categorized as moderate-to-strong immunostaining intensities. Credit:B

Updated on: December 27,2023 6

First test of anti-cancer agent PAC-1 in human clinical trials shows promise

by Diana Yates,University of Illinois at Urbana-ChampaignProcaspase-3 (PC-3) expressions in diverse tumor histologies categorized as moderate-to-strong immunostaining intensities. Credit:B

Updated on:December 27,2023 6

Strategy could remove metastatic traits and drug resistance from lung cancer cells

byThe Korea Advanced Institute of Science and Technology (KAIST)Figure 1. Construction of the mathematical model of the regulatory network to represent the EMT phenotype based on the interaction

Updated on: December 19,2023 10

Strategy could remove metastatic traits and drug resistance from lung cancer cells

byThe Korea Advanced Institute of Science and Technology (KAIST)Figure 1. Construction of the mathematical model of the regulatory network to represent the EMT phenotype based on the interaction

Updated on:December 19,2023 10