Combination therapy overcomes BET inhibitor resistance, shows study

bySt. Jude Children's Research HospitalStudy first author Shaela Fields (Wright), from the lab of Chunliang, Li, PhD, St. Jude Department of Tumor Cell Biology, led research to understand BE

Updated on: January 16,2024

Combination therapy overcomes BET inhibitor resistance, shows study

bySt. Jude Children's Research HospitalStudy first author Shaela Fields (Wright), from the lab of Chunliang, Li, PhD, St. Jude Department of Tumor Cell Biology, led research to understand BE

Updated on:January 16,2024

Study finds behavior matters far more to lifetime exposure to cancer-causing radiation than previously believed

by Allie Miller,University of CalgaryResidential radon exposure periods modified by radon awareness behavior and test decision-making that can differ by age, sex/gender or parental status. Credi

Updated on: January 23,2024

Study finds behavior matters far more to lifetime exposure to cancer-causing radiation than previously believed

by Allie Miller,University of CalgaryResidential radon exposure periods modified by radon awareness behavior and test decision-making that can differ by age, sex/gender or parental status. Credi

Updated on:January 23,2024

Specifically designed diets demonstrate a 'powerful ability' to prevent tumorigenesis, delay tumor growth

byThe Spanish National Cancer Research CentrePrecision nutrition in cancer therapyPrecision nutrition takes into account genetic, physiological and lifestyle factors to develop personalized diet

Updated on: January 22,2024

Specifically designed diets demonstrate a 'powerful ability' to prevent tumorigenesis, delay tumor growth

byThe Spanish National Cancer Research CentrePrecision nutrition in cancer therapyPrecision nutrition takes into account genetic, physiological and lifestyle factors to develop personalized diet

Updated on:January 22,2024

Study reveals somatic mutation profile of colorectal tumor with simultaneous APC and MLH1 germline mutations

by Zhao Weiwei; Hong Bo, Hefei Institutes of Physical Science, Chinese Academy of SciencesThe pedigree of the studied family, and hematoxylin-eosin staining of colorectal adenocarcinoma or adenomas in

Updated on: February 20,2024

Study reveals somatic mutation profile of colorectal tumor with simultaneous APC and MLH1 germline mutations

by Zhao Weiwei; Hong Bo, Hefei Institutes of Physical Science, Chinese Academy of SciencesThe pedigree of the studied family, and hematoxylin-eosin staining of colorectal adenocarcinoma or adenomas in

Updated on:February 20,2024

Drug bypasses suppressive immune cells to unleash immunotherapy

by Marta Wegorzewska,Washington University School of MedicineImmunobiologists Robert Schreiber, Ph.D., (left) and Hussein Sultan, Ph.D., of Washington University School of Medicine in St. Louis,

Updated on: August 28,2024

Drug bypasses suppressive immune cells to unleash immunotherapy

by Marta Wegorzewska,Washington University School of MedicineImmunobiologists Robert Schreiber, Ph.D., (left) and Hussein Sultan, Ph.D., of Washington University School of Medicine in St. Louis,

Updated on:August 28,2024

Mouse studies have revealed more about the mechanisms behind cancer drugs in trials

by Agency for Science, Technology and Research (A*STAR), SingaporeDNA damage (red) in the spleen of a mouse that expresses the mutant form of CDK1 that cannot be suppressed by phosphorylation. Cr

Updated on: March 01,2024

Mouse studies have revealed more about the mechanisms behind cancer drugs in trials

by Agency for Science, Technology and Research (A*STAR), SingaporeDNA damage (red) in the spleen of a mouse that expresses the mutant form of CDK1 that cannot be suppressed by phosphorylation. Cr

Updated on:March 01,2024

Workaround erases side effects of promising cell-based cancer therapy

by Bruce Goldman,Stanford University Medical CenterResearch at Stanford are looking at whether a type of immune cell known as a T cell could be taken from a cancer patient, then modified and ret

Updated on: March 01,2024

Workaround erases side effects of promising cell-based cancer therapy

by Bruce Goldman,Stanford University Medical CenterResearch at Stanford are looking at whether a type of immune cell known as a T cell could be taken from a cancer patient, then modified and ret

Updated on:March 01,2024

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud

Updated on: March 14,2024

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud

Updated on:March 14,2024

Intraventricular immunovirotherapy: A translational step forward

by Impact JournalsPutative mechanisms of toxicity. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28343A new research perspective titled "Intraventricular immunovirotherapy; a tran

Updated on: January 02,2024

Intraventricular immunovirotherapy: A translational step forward

by Impact JournalsPutative mechanisms of toxicity. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28343A new research perspective titled "Intraventricular immunovirotherapy; a tran

Updated on:January 02,2024

Inherited BRCA2 mutations linked to increased risk of childhood lymphoma

by St. Jude Children's Research HospitalInvestigators at St. Jude Children's Research Hospital have linked inherited BRCA2 gene mutations with an increased risk of non-Hodgkin lymphoma in

Updated on: May 13,2024

Inherited BRCA2 mutations linked to increased risk of childhood lymphoma

by St. Jude Children's Research HospitalInvestigators at St. Jude Children's Research Hospital have linked inherited BRCA2 gene mutations with an increased risk of non-Hodgkin lymphoma in

Updated on:May 13,2024

HPV vaccine eliminates advanced skin cancer in 97-year-old

(HealthDay)—The 9-valent human papillomavirus (HPV) vaccine could be a therapeutic option for patients with cutaneous squamous cell carcinoma when surgical management is not an option, according to a

Updated on: March 12,2024

HPV vaccine eliminates advanced skin cancer in 97-year-old

(HealthDay)—The 9-valent human papillomavirus (HPV) vaccine could be a therapeutic option for patients with cutaneous squamous cell carcinoma when surgical management is not an option, according to a

Updated on:March 12,2024

Everolimus inhibits angiogenesis and lymphangiogenesis in TP53 mutant HNSCC via STAT3/HIF-1α/VEGF pathway

by Impact Journals LLCEverolimus reduces microvessel density (MVD) and lymphatic vessel density (LVD) in TP53 mutant HNSCC xenografts. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.283

Updated on: February 03,2024

Everolimus inhibits angiogenesis and lymphangiogenesis in TP53 mutant HNSCC via STAT3/HIF-1α/VEGF pathway

by Impact Journals LLCEverolimus reduces microvessel density (MVD) and lymphatic vessel density (LVD) in TP53 mutant HNSCC xenografts. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.283

Updated on:February 03,2024