New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on: May 21,2024

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on:May 21,2024

Targeting mutation slows breast cancer spread, study finds

Credit: Pixabay/CC0 Public DomainThe progression of certain types of breast cancers can be slowed by identifying a particular genetic mutation and then quickly adapting treatment, a first-of-its-kind

Updated on: January 23,2024

Targeting mutation slows breast cancer spread, study finds

Credit: Pixabay/CC0 Public DomainThe progression of certain types of breast cancers can be slowed by identifying a particular genetic mutation and then quickly adapting treatment, a first-of-its-kind

Updated on:January 23,2024

Insurance status mediates racial, ethnic inequities in cervical cancer, finds study

by Elana GotkineInsurance status mediates racial and ethnic inequities in advanced-stage cervical cancer diagnosis, according to a study published online March 10 inJAMA Network Open.Hunter K. H

Updated on: January 23,2024

Insurance status mediates racial, ethnic inequities in cervical cancer, finds study

by Elana GotkineInsurance status mediates racial and ethnic inequities in advanced-stage cervical cancer diagnosis, according to a study published online March 10 inJAMA Network Open.Hunter K. H

Updated on:January 23,2024

New tools to manage rare eye cancer

by University College DublinTumor secretion of IL-6, IL-13, VEGF-A, and PlGF correlate with clinical characteristics in ex vivo, control-treated, primary UM patient tumors. (A) Schematic of the e

Updated on: January 29,2024

New tools to manage rare eye cancer

by University College DublinTumor secretion of IL-6, IL-13, VEGF-A, and PlGF correlate with clinical characteristics in ex vivo, control-treated, primary UM patient tumors. (A) Schematic of the e

Updated on:January 29,2024

No increased cancer risk found in rheumatology patients with history of malignancy taking DMARDS and TNF inhibitors

byAmerican College of RheumatologyFlowchart of patients included in the study. Credit: Cancer Risk with Biologic and Targeted Synthetic DMARDs in Patients with Rheumatic Diseases and Previous Ma

Updated on: January 29,2024

No increased cancer risk found in rheumatology patients with history of malignancy taking DMARDS and TNF inhibitors

byAmerican College of RheumatologyFlowchart of patients included in the study. Credit: Cancer Risk with Biologic and Targeted Synthetic DMARDs in Patients with Rheumatic Diseases and Previous Ma

Updated on:January 29,2024

Researchers discover method to 'turn off' mutated melanoma

by Boston University School of MedicineMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma is the deadliest f

Updated on: June 22,2024

Researchers discover method to 'turn off' mutated melanoma

by Boston University School of MedicineMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma is the deadliest f

Updated on:June 22,2024

Second primary malignancy risk increased after cutaneous B-cell lymphoma

by Elana GotkinePatients with primary cutaneous B-cell lymphomas (PCBCLs) have an increased risk for second primary malignancies (SPMs), according to a studypublishedonline March 19 in the

Updated on: April 06,2024

Second primary malignancy risk increased after cutaneous B-cell lymphoma

by Elana GotkinePatients with primary cutaneous B-cell lymphomas (PCBCLs) have an increased risk for second primary malignancies (SPMs), according to a studypublishedonline March 19 in the

Updated on:April 06,2024

Breast cancer test could guide treatment for more aggressive subtype

byInstitute of Cancer ResearchKi67 changes from baseline to surgery stratified by intrinsic subtype at baseline within a. Treated and b. Controls. Abbreviations: HER2-E, HER2-Enriched Subtype; L

Updated on: January 02,2024

Breast cancer test could guide treatment for more aggressive subtype

byInstitute of Cancer ResearchKi67 changes from baseline to surgery stratified by intrinsic subtype at baseline within a. Treated and b. Controls. Abbreviations: HER2-E, HER2-Enriched Subtype; L

Updated on:January 02,2024

How oncologists can ethically navigate the 'Right-To-Try' drug law

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainThe 2018 federal Right to Try Act allows patients with a life-threatening illness to be treated with drugs

Updated on: April 07,2024

How oncologists can ethically navigate the 'Right-To-Try' drug law

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainThe 2018 federal Right to Try Act allows patients with a life-threatening illness to be treated with drugs

Updated on:April 07,2024

Novel approach to study hypoxia enables identification of a marker for ovarian cancers

by Myreille Larouche,University of MontrealLong-term severe hypoxia adaptation induces EMT-like morphological changes. Credit:Cancer Gene Therapy(2024). DOI: 10.1038/s41417-024-00795

Updated on: August 28,2024

Novel approach to study hypoxia enables identification of a marker for ovarian cancers

by Myreille Larouche,University of MontrealLong-term severe hypoxia adaptation induces EMT-like morphological changes. Credit:Cancer Gene Therapy(2024). DOI: 10.1038/s41417-024-00795

Updated on:August 28,2024

Brain tumor clinical trial: Failed Alzheimer's drug that boosts effect of radiotherapy to be tested in humans this year

by Worldwide Cancer ResearchFlow chart with the design of a clinical trial with azeliragon in combination with radiotherapy in patients with brain metastases from non-small-cell lung cancer, breast ca

Updated on: January 02,2024

Brain tumor clinical trial: Failed Alzheimer's drug that boosts effect of radiotherapy to be tested in humans this year

by Worldwide Cancer ResearchFlow chart with the design of a clinical trial with azeliragon in combination with radiotherapy in patients with brain metastases from non-small-cell lung cancer, breast ca

Updated on:January 02,2024

Researchers unveil the origin of second pediatric cancers and chemotherapy-induced mutations in healthy tissues

byInstitute for Research in Biomedicine (IRB Barcelona)The origin of second solid tumors of cases 3 (A–D) and 4 (E–F). A, Eight years after the development of NB, the child presented with MRT. B

Updated on: March 30,2024

Researchers unveil the origin of second pediatric cancers and chemotherapy-induced mutations in healthy tissues

byInstitute for Research in Biomedicine (IRB Barcelona)The origin of second solid tumors of cases 3 (A–D) and 4 (E–F). A, Eight years after the development of NB, the child presented with MRT. B

Updated on:March 30,2024