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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Too often, women aren't told of sexual side effects of cancer treatments

Too often, women aren't told of sexual side effects of cancer treatments

by Cara MurezWhen a man has cancer in an area that affects sexual function, his doctor is likely to discuss it with him.But the same is not true for a woman who has cancer in a sex organ, according to

Too often, women aren't told of sexual side effects of cancer treatments

by Cara MurezWhen a man has cancer in an area that affects sexual function, his doctor is likely to discuss it with him.But the same is not true for a woman who has cancer in a sex organ, according to
Pregnancy poses no greater risk to breast cancer survivors

Pregnancy poses no greater risk to breast cancer survivors

by Oxford University PressCredit: CC0 Public DomainA recent study published in theJournal of the National Cancer Instituteindicates that pregnancy does not incur a greater risk of rel

Pregnancy poses no greater risk to breast cancer survivors

by Oxford University PressCredit: CC0 Public DomainA recent study published in theJournal of the National Cancer Instituteindicates that pregnancy does not incur a greater risk of rel
In breast-cancer prevention, race matters

In breast-cancer prevention, race matters

by The Ohio State UniversityCredit: CC0 Public DomainAfrican-American women at high risk of breast cancer are less likely than white women to pursue potentially life-saving preventive care, and r

In breast-cancer prevention, race matters

by The Ohio State UniversityCredit: CC0 Public DomainAfrican-American women at high risk of breast cancer are less likely than white women to pursue potentially life-saving preventive care, and r
Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe
Study reports blocking key enzyme boosts anti-cancer T-cell responses and resistance to immunosuppression

Study reports blocking key enzyme boosts anti-cancer T-cell responses and resistance to immunosuppression

byLouisiana State UniversityCredit:Frontiers in ImmunologyDOI: 10.3389/fimmu.2022.987298A study led by LSU Health New Orleans cancer researchers describes a novel therapeutic strateg

Study reports blocking key enzyme boosts anti-cancer T-cell responses and resistance to immunosuppression

byLouisiana State UniversityCredit:Frontiers in ImmunologyDOI: 10.3389/fimmu.2022.987298A study led by LSU Health New Orleans cancer researchers describes a novel therapeutic strateg
Minorities face longer wait times for vital lung cancer treatment, study finds

Minorities face longer wait times for vital lung cancer treatment, study finds

byUniversity of VirginiaCredit: Pixabay/CC0 Public DomainA new study has revealed significant racial disparities in how quickly minorities with the most common form of lung cancer receive potent

Minorities face longer wait times for vital lung cancer treatment, study finds

byUniversity of VirginiaCredit: Pixabay/CC0 Public DomainA new study has revealed significant racial disparities in how quickly minorities with the most common form of lung cancer receive potent
Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

by Liu Jia,Chinese Academy of SciencesCredit: Pixabay/CC0 Public DomainLactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis

Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

by Liu Jia,Chinese Academy of SciencesCredit: Pixabay/CC0 Public DomainLactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis
Researchers uncover new targets for breast cancers resistant to standard therapies

Researchers uncover new targets for breast cancers resistant to standard therapies

by Leslie Cantu,Medical University of South CarolinaSOC therapy commonly induces DNA damage, BRCAness and toxic PARP1 trapping, leading to transcriptional blockage and growth inhibition in ER+ b

Researchers uncover new targets for breast cancers resistant to standard therapies

by Leslie Cantu,Medical University of South CarolinaSOC therapy commonly induces DNA damage, BRCAness and toxic PARP1 trapping, leading to transcriptional blockage and growth inhibition in ER+ b
Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i
Resistance of mammary fibrosis to immune checkpoint therapy linked to macrophage infiltration, Wnt pathway expression

Resistance of mammary fibrosis to immune checkpoint therapy linked to macrophage infiltration, Wnt pathway expression

by Impact Journals LLCWnt pathway expression in tumors from NeuT/ATTAC mice. Credit: 2022 Yuan et al.A new research paper titled "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint

Resistance of mammary fibrosis to immune checkpoint therapy linked to macrophage infiltration, Wnt pathway expression

by Impact Journals LLCWnt pathway expression in tumors from NeuT/ATTAC mice. Credit: 2022 Yuan et al.A new research paper titled "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint
Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t
Tumors backfire on chemotherapy

Tumors backfire on chemotherapy

by Ecole Polytechnique Federale de LausanneEndothelial cells (blue/grey) internalizing exosomes (red) released from chemotherapy-treated tumors. Credit: C. Cianciaruso/I. Keklikoglou/EPFLSome pat

Tumors backfire on chemotherapy

by Ecole Polytechnique Federale de LausanneEndothelial cells (blue/grey) internalizing exosomes (red) released from chemotherapy-treated tumors. Credit: C. Cianciaruso/I. Keklikoglou/EPFLSome pat