Research raises hopes for new treatment of fusion-driven cancer

by Aarhus UniversityFusion-gene disruption strategy.ADual intron-targeting CRISPR-Cas9-mediated disruption ofRUNX1-RUNX1T1. sgRNAs targeting intron 4 ofRUNX1(orange)

Updated on: February 03,2024

Research raises hopes for new treatment of fusion-driven cancer

by Aarhus UniversityFusion-gene disruption strategy.ADual intron-targeting CRISPR-Cas9-mediated disruption ofRUNX1-RUNX1T1. sgRNAs targeting intron 4 ofRUNX1(orange)

Updated on:February 03,2024

A novel network computer model to find co-occurring mutations—researchers improve search for cancer drivers

by Tina Hilding,Washington State UniversityNumber of mutations by variant type (A) before filtering and (B) after filtering. (C) Number of genes and their role in cancer. (D) Pie chart showing t

Updated on: September 28,2024

A novel network computer model to find co-occurring mutations—researchers improve search for cancer drivers

by Tina Hilding,Washington State UniversityNumber of mutations by variant type (A) before filtering and (B) after filtering. (C) Number of genes and their role in cancer. (D) Pie chart showing t

Updated on:September 28,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on: February 18,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on:February 18,2024

Potential probe for early ovarian cancer

by Anivarya Kumar,Vanderbilt UniversityFigure 1. (a) Structure of COX-2-selective inhibitors (celecoxib, rofecoxib, and valdecoxib) and COX-1-selective inhibitors (SC560, P6/18F-P6, and VU048783

Updated on: April 20,2024

Potential probe for early ovarian cancer

by Anivarya Kumar,Vanderbilt UniversityFigure 1. (a) Structure of COX-2-selective inhibitors (celecoxib, rofecoxib, and valdecoxib) and COX-1-selective inhibitors (SC560, P6/18F-P6, and VU048783

Updated on:April 20,2024

Researchers make next move in the fight against ovarian cancer

by University of Arizona College of EngineeringGraphic representation of falloposcope image resolution on the University of Arizona's "Block A." Credit: University of ArizonaOvarian canc

Updated on: June 04,2024

Researchers make next move in the fight against ovarian cancer

by University of Arizona College of EngineeringGraphic representation of falloposcope image resolution on the University of Arizona's "Block A." Credit: University of ArizonaOvarian canc

Updated on:June 04,2024

Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

by Rebecca Brierley,University at BuffaloGraphical abstract. Credit:Molecular & Cellular Proteomics(2022). DOI: 10.1016/j.mcpro.2022.100409Researchers from the University at Buff

Updated on: February 20,2024

Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

by Rebecca Brierley,University at BuffaloGraphical abstract. Credit:Molecular & Cellular Proteomics(2022). DOI: 10.1016/j.mcpro.2022.100409Researchers from the University at Buff

Updated on:February 20,2024

Race/ethnicity, socioeconomics, age contribute to disparities in cancer death

by Elana GotkineFactors contributing to disparities in cancer death include race/ethnicity, socioeconomic status, geographic location, and age, according to a study published online Nov. 14 inCA

Updated on: April 07,2024

Race/ethnicity, socioeconomics, age contribute to disparities in cancer death

by Elana GotkineFactors contributing to disparities in cancer death include race/ethnicity, socioeconomic status, geographic location, and age, according to a study published online Nov. 14 inCA

Updated on:April 07,2024

Swapping meat for 'mycoprotein' may protect against bowel cancer

by Northumbria UniversityVegetarian chilli con carne made with Quorn mycoprotein. Credit: QuornResearchers from Northumbria University have found that swapping red and processed meat for Quorn&#3

Updated on: February 23,2024

Swapping meat for 'mycoprotein' may protect against bowel cancer

by Northumbria UniversityVegetarian chilli con carne made with Quorn mycoprotein. Credit: QuornResearchers from Northumbria University have found that swapping red and processed meat for Quorn&#3

Updated on:February 23,2024

A code for reprogramming immune sentinels

by Lund UniversityArtistic rendering of the surface of a human dendritic cell illustrating sheet-like processes that fold back onto the membrane surface. Credit: National Institutes of Health (NI

Updated on: May 23,2024

A code for reprogramming immune sentinels

by Lund UniversityArtistic rendering of the surface of a human dendritic cell illustrating sheet-like processes that fold back onto the membrane surface. Credit: National Institutes of Health (NI

Updated on:May 23,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on: May 23,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on:May 23,2024

Study uncovers how B cells react to skin cancer

by King's College LondonSpatial transcriptomic coupled with high throughput intratumoral antibody repertoire analyses suggest an active but aberrant B cell response.aRepresentativ

Updated on: February 23,2024

Study uncovers how B cells react to skin cancer

by King's College LondonSpatial transcriptomic coupled with high throughput intratumoral antibody repertoire analyses suggest an active but aberrant B cell response.aRepresentativ

Updated on:February 23,2024

Molecular change to immunotherapy antibody could accelerate immune response to cancer

byWeizmann Institute of ScienceTissue sample of a particularly aggressive skin cancer reveals immune cells (yellow) that express on their surfaces a “brake pedal” receptor called FcgIIb (purple)

Updated on: January 02,2024

Molecular change to immunotherapy antibody could accelerate immune response to cancer

byWeizmann Institute of ScienceTissue sample of a particularly aggressive skin cancer reveals immune cells (yellow) that express on their surfaces a “brake pedal” receptor called FcgIIb (purple)

Updated on:January 02,2024