Research reveals functional targets of oncogenic HOXA9 protein in high-risk pediatric leukemia

by St. Jude Children's Research HospitalSchematic diagram summarizing this study. Our work interrogated the transcription factor function of HOXA9 in MLL-r leukemias by targeting HOXA9-bound

Updated on: July 02,2024 5

Research reveals functional targets of oncogenic HOXA9 protein in high-risk pediatric leukemia

by St. Jude Children's Research HospitalSchematic diagram summarizing this study. Our work interrogated the transcription factor function of HOXA9 in MLL-r leukemias by targeting HOXA9-bound

Updated on:July 02,2024 5

Immunotherapy research offers new hope for children with primary liver carcinomas

by Jessica Cerretani,Children's Hospital BostonSwimmers plots for each individual patient course. Credit:eBioMedicine(2024). DOI: 10.1016/j.ebiom.2024.105147Pediatric hepatocellu

Updated on: September 07,2024 0

Immunotherapy research offers new hope for children with primary liver carcinomas

by Jessica Cerretani,Children's Hospital BostonSwimmers plots for each individual patient course. Credit:eBioMedicine(2024). DOI: 10.1016/j.ebiom.2024.105147Pediatric hepatocellu

Updated on:September 07,2024 0

Researchers find out why some lung tumors avoid immunotherapy, and learn how to predict this in advance

by Josep Carreras Leukaemia Research InstituteGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101006The oncogenic activation of MYC, a critical gene i

Updated on: February 18,2024 12

Researchers find out why some lung tumors avoid immunotherapy, and learn how to predict this in advance

by Josep Carreras Leukaemia Research InstituteGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101006The oncogenic activation of MYC, a critical gene i

Updated on:February 18,2024 12

Research could lead to better understanding of pancreatic cancer

by University of SurreyAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainSurrey's BioProChem group has developed a biomaterial based c

Updated on: June 28,2024 6

Research could lead to better understanding of pancreatic cancer

by University of SurreyAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainSurrey's BioProChem group has developed a biomaterial based c

Updated on:June 28,2024 6

Researchers find a 'critical need' for whole genome sequencing of young cancer patients

by St. Jude Children's Research HospitalSt. Jude investigators (from left) Michael Rusch, Sheila Shurtleff, Ph.D., Jinghui Zhang, Ph.D., and Scott Newman, Ph.D. Credit: St. Jude Children'

Updated on: June 22,2024 4

Researchers find a 'critical need' for whole genome sequencing of young cancer patients

by St. Jude Children's Research HospitalSt. Jude investigators (from left) Michael Rusch, Sheila Shurtleff, Ph.D., Jinghui Zhang, Ph.D., and Scott Newman, Ph.D. Credit: St. Jude Children'

Updated on:June 22,2024 4

Researchers report on ctDNA-based detection of residual disease prognostic for resected CRC

by Elana GotkineFor patients with radically resected, stage II to IV colorectal cancer (CRC), circulating tumor (ct)DNA-based detection of molecular residual disease (MRD) in response to adjuvant chem

Updated on: March 05,2024 12

Researchers report on ctDNA-based detection of residual disease prognostic for resected CRC

by Elana GotkineFor patients with radically resected, stage II to IV colorectal cancer (CRC), circulating tumor (ct)DNA-based detection of molecular residual disease (MRD) in response to adjuvant chem

Updated on:March 05,2024 12

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on: March 30,2024 0

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on:March 30,2024 0

Researchers discover 40 genes involved in early development of myeloma

by Sarah Wells, The Institute of Cancer ResearchMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0Researchers have revealed 40 ge

Updated on: June 24,2024 3

Researchers discover 40 genes involved in early development of myeloma

by Sarah Wells, The Institute of Cancer ResearchMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0Researchers have revealed 40 ge

Updated on:June 24,2024 3

Researchers identify new gene mutation in familial thyroid cancers

by Pennsylvania State UniversityCredit: CC0 Public DomainResearchers from Penn State College of Medicine identified a new gene mutation that may cause a type of familial thyroid cancer. Dr. Darri

Updated on: June 04,2024 7

Researchers identify new gene mutation in familial thyroid cancers

by Pennsylvania State UniversityCredit: CC0 Public DomainResearchers from Penn State College of Medicine identified a new gene mutation that may cause a type of familial thyroid cancer. Dr. Darri

Updated on:June 04,2024 7

Researcher and her students discover lesser-known gene associated with breast cancer

by Villanova UniversityCredit: Villanova UniversityVillanova University biology professor Janice Knepper, PhD, and her students have discovered that a gene, previously poorly characterized, can b

Updated on: March 01,2024 14

Researcher and her students discover lesser-known gene associated with breast cancer

by Villanova UniversityCredit: Villanova UniversityVillanova University biology professor Janice Knepper, PhD, and her students have discovered that a gene, previously poorly characterized, can b

Updated on:March 01,2024 14

Multigene testing replacing BRCA tests for breast cancer risk, researcher says

by Stanford University Medical CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014

Updated on: June 24,2024 8

Multigene testing replacing BRCA tests for breast cancer risk, researcher says

by Stanford University Medical CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014

Updated on:June 24,2024 8

Induced pluripotent stem cells could serve as cancer vaccine, researchers say

by Stanford University Medical CenterCredit: CC0 Public DomainInduced pluripotent stem cells, or iPS cells, are a keystone of regenerative medicine. Outside the body, they can be coaxed to become

Updated on: June 06,2024 5

Induced pluripotent stem cells could serve as cancer vaccine, researchers say

by Stanford University Medical CenterCredit: CC0 Public DomainInduced pluripotent stem cells, or iPS cells, are a keystone of regenerative medicine. Outside the body, they can be coaxed to become

Updated on:June 06,2024 5