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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part
Research could lead to better understanding of pancreatic cancer

Research could lead to better understanding of pancreatic cancer

by University of SurreyAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainSurrey's BioProChem group has developed a biomaterial based c

Research could lead to better understanding of pancreatic cancer

by University of SurreyAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainSurrey's BioProChem group has developed a biomaterial based c
Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo
Researchers uncover potential biomarkers of positive response to immunotherapy

Researchers uncover potential biomarkers of positive response to immunotherapy

by Denise Heady,University of California, Los AngelesResponse to ICI or MAPKi therapy is associated with increased T cell infiltration and enhanced interferon gamma (IFNγ) pathway activity in th

Researchers uncover potential biomarkers of positive response to immunotherapy

by Denise Heady,University of California, Los AngelesResponse to ICI or MAPKi therapy is associated with increased T cell infiltration and enhanced interferon gamma (IFNγ) pathway activity in th
Researchers circumvent radiation resistance in subtype of brain tumors

Researchers circumvent radiation resistance in subtype of brain tumors

by University of MichiganMutant IDH1 glioma invading the normal brain structures. Non-tumor astrocytes are stained using an anti-GFAP antibody and are seen in brown. Credit: Maria Castro, Ph.D.It

Researchers circumvent radiation resistance in subtype of brain tumors

by University of MichiganMutant IDH1 glioma invading the normal brain structures. Non-tumor astrocytes are stained using an anti-GFAP antibody and are seen in brown. Credit: Maria Castro, Ph.D.It
The search to discover why 'outliers' survive deadliest cancers

The search to discover why 'outliers' survive deadliest cancers

by Isabelle TOURNÉThe biotech start-up Cure51 is working on the first global molecular database of exceptional survivors of cancer.When Herve found out he had glioblastoma—the most aggressive form of

The search to discover why 'outliers' survive deadliest cancers

by Isabelle TOURNÉThe biotech start-up Cure51 is working on the first global molecular database of exceptional survivors of cancer.When Herve found out he had glioblastoma—the most aggressive form of
Researchers examine the metabolic effects of an oral blood cancer drug

Researchers examine the metabolic effects of an oral blood cancer drug

by The Mount Sinai HospitalCredit: CC0 Public DomainA popular cancer drug is associated with significant weight gain and increased systolic blood pressure, researchers from the Icahn School of Me

Researchers examine the metabolic effects of an oral blood cancer drug

by The Mount Sinai HospitalCredit: CC0 Public DomainA popular cancer drug is associated with significant weight gain and increased systolic blood pressure, researchers from the Icahn School of Me
Researchers solving treatment resistance in most common breast cancer

Researchers solving treatment resistance in most common breast cancer

by University of Pittsburgh Schools of the Health SciencesMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainAt Magee-Womens Research Institute (MWRI

Researchers solving treatment resistance in most common breast cancer

by University of Pittsburgh Schools of the Health SciencesMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainAt Magee-Womens Research Institute (MWRI
Cell lines deserve unique considerations when creating research protections, researchers say

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi
Researchers shed light on signaling pathway responsible for head and neck cancers

Researchers shed light on signaling pathway responsible for head and neck cancers

by Gina DiGravio,Boston University School of MedicineCausal Inference Models of Interactions Between Pathways/Cell States in Head and Neck Cancer scRNAseq Data. A. Causal inference graphs indica

Researchers shed light on signaling pathway responsible for head and neck cancers

by Gina DiGravio,Boston University School of MedicineCausal Inference Models of Interactions Between Pathways/Cell States in Head and Neck Cancer scRNAseq Data. A. Causal inference graphs indica
Researchers advance role of circulating tumor DNA to detect early melanoma growth

Researchers advance role of circulating tumor DNA to detect early melanoma growth

by Johns Hopkins University School of MedicineEvidence of disease activity detected in circulating tumor DNA (ctDNA) predicts radiographic melanoma progression. Credit: Johns Hopkins Kimmel Cance

Researchers advance role of circulating tumor DNA to detect early melanoma growth

by Johns Hopkins University School of MedicineEvidence of disease activity detected in circulating tumor DNA (ctDNA) predicts radiographic melanoma progression. Credit: Johns Hopkins Kimmel Cance
Research points to an immunotherapy to overcome resistant leukemia

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula