First genomic study of puberty yields insights into development and cancer

by Huntsman Cancer InstituteBradley Cairns, Ph.D. Credit: Huntsman Cancer InstituteIn the first-ever genome-scale analysis of the puberty process in humans, researchers at Huntsman Cancer Institute (H

Updated on: December 20,2023 19

First genomic study of puberty yields insights into development and cancer

by Huntsman Cancer InstituteBradley Cairns, Ph.D. Credit: Huntsman Cancer InstituteIn the first-ever genome-scale analysis of the puberty process in humans, researchers at Huntsman Cancer Institute (H

Updated on:December 20,2023 19

Pregnancy possible after chemotherapy for breast cancer patients, but many no longer wish

byEuropean Society for Medical OncologyDr. Jérôme Martin-Babau from Centre Armoricain de Radiothérapie, Imagerie Médicale et Oncologie in Plérin, France, study author. Credit: European Society f

Updated on: December 18,2023 11

Pregnancy possible after chemotherapy for breast cancer patients, but many no longer wish

byEuropean Society for Medical OncologyDr. Jérôme Martin-Babau from Centre Armoricain de Radiothérapie, Imagerie Médicale et Oncologie in Plérin, France, study author. Credit: European Society f

Updated on:December 18,2023 11

What kind of support do breast cancer patients want? Food, rides and prayer

by Tisha Felder,The ConversationCredit: AI-generated imageFor 31 days every October, pink ribbons and #BCAM hashtags flood our social media timelines with information about breast cancer. That&#

Updated on: December 18,2023 19

What kind of support do breast cancer patients want? Food, rides and prayer

by Tisha Felder,The ConversationCredit: AI-generated imageFor 31 days every October, pink ribbons and #BCAM hashtags flood our social media timelines with information about breast cancer. That&#

Updated on:December 18,2023 19

Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

byUniversity of BarcelonaGenetic models to mimic SMAD2/3 alterations in patient-derived ADC-TAFs and SCC-TAFs. a–c, Fold SMAD3 (a) and SMAD2 (b) mRNA and corresponding ratio (c) in primary lung

Updated on: December 21,2023 13

Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

byUniversity of BarcelonaGenetic models to mimic SMAD2/3 alterations in patient-derived ADC-TAFs and SCC-TAFs. a–c, Fold SMAD3 (a) and SMAD2 (b) mRNA and corresponding ratio (c) in primary lung

Updated on:December 21,2023 13

Precision oncology approach shows potential for high grade gliomas harboring a genetic mutation

by Nicole Fawcett,University of MichiganImmunostaining in a genetically engineered pediatric high grade glioma model harboring the H3-G34R mutation. Tumor cells are shown in green, nuclei in blu

Updated on: December 26,2023 10

Precision oncology approach shows potential for high grade gliomas harboring a genetic mutation

by Nicole Fawcett,University of MichiganImmunostaining in a genetically engineered pediatric high grade glioma model harboring the H3-G34R mutation. Tumor cells are shown in green, nuclei in blu

Updated on:December 26,2023 10

Hormone resistance in breast cancer linked to DNA 'rewiring'

byGarvan Institute of Medical ResearchCredit: CC0 Public DomainEpigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatm

Updated on: December 20,2023 16

Hormone resistance in breast cancer linked to DNA 'rewiring'

byGarvan Institute of Medical ResearchCredit: CC0 Public DomainEpigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatm

Updated on:December 20,2023 16

Researchers clarify role of SMYD3 enzyme in prostate cancer progression

by Sarah Hansen,University of Maryland Baltimore CountySMYD3 loss impedes PCa progression.(A) Expression ofSMYD3mRNA from TCGA [GTEX normal (n= 105), TCGA tumor adjacent normal

Updated on: December 26,2023 5

Researchers clarify role of SMYD3 enzyme in prostate cancer progression

by Sarah Hansen,University of Maryland Baltimore CountySMYD3 loss impedes PCa progression.(A) Expression ofSMYD3mRNA from TCGA [GTEX normal (n= 105), TCGA tumor adjacent normal

Updated on:December 26,2023 5

Shutting down backup genes leads to cancer remission in mice

by Jim Lynch,University of MichiganAbhinav Achreja, PhD, Research Fellow at the University of Michigan Biomedical Engineering and Deepak Nagrath, Ph.D. Associate Professor of Biomedical Engineer

Updated on: December 22,2023 9

Shutting down backup genes leads to cancer remission in mice

by Jim Lynch,University of MichiganAbhinav Achreja, PhD, Research Fellow at the University of Michigan Biomedical Engineering and Deepak Nagrath, Ph.D. Associate Professor of Biomedical Engineer

Updated on:December 22,2023 9

Cancer mortality continues steady decline, driven by progress against lung cancer

byAmerican Cancer SocietyTrends in Overall Cancer Mortality Rates by Sex, United States, 1930 to 2017. Rates are age adjusted to the 2000 US standard population Credit: American Cancer SocietyTh

Updated on: December 22,2023 19

Cancer mortality continues steady decline, driven by progress against lung cancer

byAmerican Cancer SocietyTrends in Overall Cancer Mortality Rates by Sex, United States, 1930 to 2017. Rates are age adjusted to the 2000 US standard population Credit: American Cancer SocietyTh

Updated on:December 22,2023 19

High BMI may improve cancer survival

byFlinders UniversityDr. Ganessan Kichenadasse from the Flinders Centre for Innovation in Cancer, South Australia. Credit: Flinders UniversityAbove average or high BMI—often linked to cancers, d

Updated on: December 20,2023 24

High BMI may improve cancer survival

byFlinders UniversityDr. Ganessan Kichenadasse from the Flinders Centre for Innovation in Cancer, South Australia. Credit: Flinders UniversityAbove average or high BMI—often linked to cancers, d

Updated on:December 20,2023 24

Pinpointing the prevalence of mismatch repair (MMR)-deficient rectal adenocarcinomas

byBrigham and Women's HospitalCredit: Pixabay/CC0 Public DomainA widely-circulated clinical trial published earlier this year in theNew England Journal of Medicine (NEJM)describe

Updated on: December 26,2023 10

Pinpointing the prevalence of mismatch repair (MMR)-deficient rectal adenocarcinomas

byBrigham and Women's HospitalCredit: Pixabay/CC0 Public DomainA widely-circulated clinical trial published earlier this year in theNew England Journal of Medicine (NEJM)describe

Updated on:December 26,2023 10

Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

byElsevierA: Comparison of clinical assay variant allele fraction (VAF) and Ion Torrent Genexus VAF showed high correlation (r2= 0.98) across a broad range of VAFs, including both in-house

Updated on: December 22,2023 9

Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

byElsevierA: Comparison of clinical assay variant allele fraction (VAF) and Ion Torrent Genexus VAF showed high correlation (r2= 0.98) across a broad range of VAFs, including both in-house

Updated on:December 22,2023 9