Structural analysis reveals an unexpected mechanism for a cancer drug

by Tim Stephens,University of California - Santa CruzThe breast cancer drug palbociclib (grey) interacts with its target protein CDK4 (green) in this structural model. Binding of the activator p

Updated on: December 22,2023

Structural analysis reveals an unexpected mechanism for a cancer drug

by Tim Stephens,University of California - Santa CruzThe breast cancer drug palbociclib (grey) interacts with its target protein CDK4 (green) in this structural model. Binding of the activator p

Updated on:December 22,2023

Obesity is a risk factor for cardiotoxicity in chemotherapy-treated patients with breast cancer

byPublic Library of ScienceObesity is associated with a three-fold increased risk of cardiotoxicity in chemotherapy-treated patients with early-stage breast cancer, regardless of other predictor

Updated on: December 22,2023

Obesity is a risk factor for cardiotoxicity in chemotherapy-treated patients with breast cancer

byPublic Library of ScienceObesity is associated with a three-fold increased risk of cardiotoxicity in chemotherapy-treated patients with early-stage breast cancer, regardless of other predictor

Updated on:December 22,2023

Scientists uncover potential 'electrical language' of breast cancer cells

by Caroline Brogan,Imperial College LondonA wave of voltage fluctuations seen across the cells. Credit: Imperial College LondonNew research has found variable voltages in the membranes of breast

Updated on: December 27,2023

Scientists uncover potential 'electrical language' of breast cancer cells

by Caroline Brogan,Imperial College LondonA wave of voltage fluctuations seen across the cells. Credit: Imperial College LondonNew research has found variable voltages in the membranes of breast

Updated on:December 27,2023

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on: December 22,2023

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on:December 22,2023

Consumer health: What is lung cancer screening, and who needs it?

by Laurel KellyCredit: Pixabay/CC0 Public DomainLung cancer is the leading cause of cancer deaths in the U.S., according to the American Cancer Society. Lung cancer claims more lives each year than co

Updated on: December 18,2023

Consumer health: What is lung cancer screening, and who needs it?

by Laurel KellyCredit: Pixabay/CC0 Public DomainLung cancer is the leading cause of cancer deaths in the U.S., according to the American Cancer Society. Lung cancer claims more lives each year than co

Updated on:December 18,2023

Non-hormonal therapy reduces hot flashes and night sweats in women who have been diagnosed with breast cancer

by Cheryl Critchley,Monash UniversityCredit: Pixabay/CC0 Public DomainA Monash University-led trial of a new drug known as Q-122 therapy significantly reduced the number and severity of hot flas

Updated on: December 22,2023

Non-hormonal therapy reduces hot flashes and night sweats in women who have been diagnosed with breast cancer

by Cheryl Critchley,Monash UniversityCredit: Pixabay/CC0 Public DomainA Monash University-led trial of a new drug known as Q-122 therapy significantly reduced the number and severity of hot flas

Updated on:December 22,2023

How dangerous is it for lung cancer patients to skip radiation treatments?

by Cara MurezAs doctors work toward developing more personalized cancer care, a new study looks at whether lung cancer patients can miss a few days of radiation treatment and make them up with a highe

Updated on: December 22,2023

How dangerous is it for lung cancer patients to skip radiation treatments?

by Cara MurezAs doctors work toward developing more personalized cancer care, a new study looks at whether lung cancer patients can miss a few days of radiation treatment and make them up with a highe

Updated on:December 22,2023

Pathogenesis to management of hepatocellular carcinoma

by Impact JournalsMolecular pathways and targeted therapeutics in hepatocellular carcinoma. Abbreviations: APC: antigen presenting cell; AXL is a cell surface receptor tyrosine kinase, part of the TAM

Updated on: December 22,2023

Pathogenesis to management of hepatocellular carcinoma

by Impact JournalsMolecular pathways and targeted therapeutics in hepatocellular carcinoma. Abbreviations: APC: antigen presenting cell; AXL is a cell surface receptor tyrosine kinase, part of the TAM

Updated on:December 22,2023

When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

by Jaclyn Dunne,Medical University of South CarolinaGraphical abstract. Credit:European Journal of Medicinal Chemistry(2022). DOI: 10.1016/j.ejmech.2022.114818A Medical University of

Updated on: December 20,2023

When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

by Jaclyn Dunne,Medical University of South CarolinaGraphical abstract. Credit:European Journal of Medicinal Chemistry(2022). DOI: 10.1016/j.ejmech.2022.114818A Medical University of

Updated on:December 20,2023

Scientists develop mathematical model to evaluate potential cancer treatment protocols

by Luke Auburn,Rochester Institute of TechnologyCredit: Unsplash/CC0 Public DomainA Rochester Institute of Technology scientist helped develop a new mathematical model that could aid doctors and

Updated on: December 27,2023

Scientists develop mathematical model to evaluate potential cancer treatment protocols

by Luke Auburn,Rochester Institute of TechnologyCredit: Unsplash/CC0 Public DomainA Rochester Institute of Technology scientist helped develop a new mathematical model that could aid doctors and

Updated on:December 27,2023

Polygenic risk scores may miss the mark when predicting aggressive prostate cancers

by Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainAccording to a research letter published inJAMA Internal Medicine, prostate cancer screening frequently results in biopsies tha

Updated on: December 21,2023

Polygenic risk scores may miss the mark when predicting aggressive prostate cancers

by Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainAccording to a research letter published inJAMA Internal Medicine, prostate cancer screening frequently results in biopsies tha

Updated on:December 21,2023

Prozac fights deadly childhood brain cancer

by Hayley Jarvis,Brunel UniversityKiller T cells surround a cancer cell. Credit: NIHThe anti-depressant drug Prozac could be used to tackle one of the deadliest childhood tumours and possibly ot

Updated on: December 22,2023

Prozac fights deadly childhood brain cancer

by Hayley Jarvis,Brunel UniversityKiller T cells surround a cancer cell. Credit: NIHThe anti-depressant drug Prozac could be used to tackle one of the deadliest childhood tumours and possibly ot

Updated on:December 22,2023