Study reveals how stem cells respond to environmental signals, with implications for IBD and colorectal cancer

byThe Hospital for Sick ChildrenModel for PIEZO mechanosensing of the ISC niche. Credit:Science(2024). DOI: 10.1126/science.adj7615A new study from The Hospital for Sick Children (Si

Updated on: December 10,2024

Study reveals how stem cells respond to environmental signals, with implications for IBD and colorectal cancer

byThe Hospital for Sick ChildrenModel for PIEZO mechanosensing of the ISC niche. Credit:Science(2024). DOI: 10.1126/science.adj7615A new study from The Hospital for Sick Children (Si

Updated on:December 10,2024

Scientists find new marker that predicts early recurrence of breast cancer

byMedical College of WisconsinPD-L2 immunostaining in ER+ breast cancer. (A-C; brown signal) Immunohistochemistry of PD-L2 using diaminobenzidine chromogen and (D-F; red signal) immunofluorescen

Updated on: December 27,2023

Scientists find new marker that predicts early recurrence of breast cancer

byMedical College of WisconsinPD-L2 immunostaining in ER+ breast cancer. (A-C; brown signal) Immunohistochemistry of PD-L2 using diaminobenzidine chromogen and (D-F; red signal) immunofluorescen

Updated on:December 27,2023

Scientists develop new targeted therapeutic strategies to fight liver metastasis

by Qiu Rong, University of Science and Technology of ChinaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI157937The research group led by Prof. Zeng Zhu

Updated on: December 27,2023

Scientists develop new targeted therapeutic strategies to fight liver metastasis

by Qiu Rong, University of Science and Technology of ChinaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI157937The research group led by Prof. Zeng Zhu

Updated on:December 27,2023

GZ17-6.02 with bexarotene kills mycosis fungoides cells: Study

by Impact Journals LLCCombined macroautophagy and CD95 death receptor signaling facilitate additional tumor cell killing by GZ17-6.02. Credit: 2024 Booth et al.A new research paper titled "GZ17-6

Updated on: May 26,2024

GZ17-6.02 with bexarotene kills mycosis fungoides cells: Study

by Impact Journals LLCCombined macroautophagy and CD95 death receptor signaling facilitate additional tumor cell killing by GZ17-6.02. Credit: 2024 Booth et al.A new research paper titled "GZ17-6

Updated on:May 26,2024

Exposing cancers to bacteria reminds first responder immune cells which side they're on

byGarvan InstituteCancer cells (green) being attacked by neutrophils (red) in the collagen structure (blue) of a tumour’s microenvironment. Credit: Jacqueline Bailey / Dr Chtanova's Innate T

Updated on: December 26,2023

Exposing cancers to bacteria reminds first responder immune cells which side they're on

byGarvan InstituteCancer cells (green) being attacked by neutrophils (red) in the collagen structure (blue) of a tumour’s microenvironment. Credit: Jacqueline Bailey / Dr Chtanova's Innate T

Updated on:December 26,2023

Locally advanced cervical cancer: Better odds using personalized brachytherapy

byMedical University of ViennaCredit: AI-generated imageCervical cancer is the cancer with the fourth highest mortality rate among women worldwide. Locally advanced cervical cancer (LACC) is tre

Updated on: December 26,2023

Locally advanced cervical cancer: Better odds using personalized brachytherapy

byMedical University of ViennaCredit: AI-generated imageCervical cancer is the cancer with the fourth highest mortality rate among women worldwide. Locally advanced cervical cancer (LACC) is tre

Updated on:December 26,2023

New study categorizes and examines four different types of model related to cancerous tumors

by John Stevenson,City University LondonCategories of model and PubMed entries. Credit: Dr Constantino Carlos Reyes AldasoroThe term model is employed quite widely in science and technology.Rese

Updated on: January 07,2024

New study categorizes and examines four different types of model related to cancerous tumors

by John Stevenson,City University LondonCategories of model and PubMed entries. Credit: Dr Constantino Carlos Reyes AldasoroThe term model is employed quite widely in science and technology.Rese

Updated on:January 07,2024

Researchers uncover new clues to origins of the most common pediatric kidney cancer

by Children's Hospital Los AngelesSIX2+CITED1+ cells in hFK and WT have different transcriptional signatures. A,B) Periodic acid Schiff (PAS, left, whole image) and H&E (right, close-up i

Updated on: February 20,2024

Researchers uncover new clues to origins of the most common pediatric kidney cancer

by Children's Hospital Los AngelesSIX2+CITED1+ cells in hFK and WT have different transcriptional signatures. A,B) Periodic acid Schiff (PAS, left, whole image) and H&E (right, close-up i

Updated on:February 20,2024

Deep learning–based virtual staining of tissue facilitates rapid assessment of breast cancer biomarker

byUCLA Engineering Institute for Technology AdvancementVirtual HER2 staining of unlabeled breast tissue sections using deep learning. Credit: Ozcan Lab @ UCLA.Breast cancer is one the leading ca

Updated on: December 25,2023

Deep learning–based virtual staining of tissue facilitates rapid assessment of breast cancer biomarker

byUCLA Engineering Institute for Technology AdvancementVirtual HER2 staining of unlabeled breast tissue sections using deep learning. Credit: Ozcan Lab @ UCLA.Breast cancer is one the leading ca

Updated on:December 25,2023

Magrolimab/Azacitidine Combo Shows Efficacy for Untreated TP53-Mutant AML

December 2023Leah LawrencePatients with previously untreated acute myeloid leukemia (AML) who were not candidates for intensive chemotherapy experienced disease response when treated with a combinatio

Updated on: February 18,2024

Magrolimab/Azacitidine Combo Shows Efficacy for Untreated TP53-Mutant AML

December 2023Leah LawrencePatients with previously untreated acute myeloid leukemia (AML) who were not candidates for intensive chemotherapy experienced disease response when treated with a combinatio

Updated on:February 18,2024

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on: October 26,2024

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on:October 26,2024

Blood pressure drug may prevent immunotherapy-induced brain swelling in patients with glioblastoma

byMassachusetts General HospitalICB increases GBM vascular leakage and induces brain edema. MR T2-weighted-Fluid-Attenuated Inversion Recovery (T2-FLAIR) images obtained from a recurrent GBM pat

Updated on: December 26,2023

Blood pressure drug may prevent immunotherapy-induced brain swelling in patients with glioblastoma

byMassachusetts General HospitalICB increases GBM vascular leakage and induces brain edema. MR T2-weighted-Fluid-Attenuated Inversion Recovery (T2-FLAIR) images obtained from a recurrent GBM pat

Updated on:December 26,2023