Major response to immunotherapy in early-stage mismatch repair deficient colon cancer

byEuropean Society for Medical OncologyCredit:Annals of OncologyPre-operative treatment with a combination of the immune checkpoint inhibitors nivolumab and ipilimumab achieves major patho

Updated on: December 18,2023

Major response to immunotherapy in early-stage mismatch repair deficient colon cancer

byEuropean Society for Medical OncologyCredit:Annals of OncologyPre-operative treatment with a combination of the immune checkpoint inhibitors nivolumab and ipilimumab achieves major patho

Updated on:December 18,2023

Hodgkin lymphoma survivors show signs of dementia in early adulthood

by Leslie Orr,University of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainIn a new study, the majority of individuals treated as children for Hodgkin lymphoma who are now in their 30s

Updated on: December 25,2023

Hodgkin lymphoma survivors show signs of dementia in early adulthood

by Leslie Orr,University of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainIn a new study, the majority of individuals treated as children for Hodgkin lymphoma who are now in their 30s

Updated on:December 25,2023

Method that uses combination of immune cells could provide clearer prognoses

by Elin Bäckström,Swedish Research CouncilPrognostic value of CD8+T cells and CD68+CD163+macrophages revealed by comprehensive characterization of immune cell subsets in 286 therapy-

Updated on: January 04,2024

Method that uses combination of immune cells could provide clearer prognoses

by Elin Bäckström,Swedish Research CouncilPrognostic value of CD8+T cells and CD68+CD163+macrophages revealed by comprehensive characterization of immune cell subsets in 286 therapy-

Updated on:January 04,2024

Study maps alterations that make melanoma more severe, could lead to better therapies and diagnosis

by André Julião,FAPESPStudy design, resources and methodology. A major aim (steps 1–2) is the discovery and validation of genome-wide methylation alterations associated with the UV mutational si

Updated on: February 20,2024

Study maps alterations that make melanoma more severe, could lead to better therapies and diagnosis

by André Julião,FAPESPStudy design, resources and methodology. A major aim (steps 1–2) is the discovery and validation of genome-wide methylation alterations associated with the UV mutational si

Updated on:February 20,2024

Genetic test could guide use of cancer chemotherapy

by Ellie Cawthera,Imperial College LondonDiscovery ofKRASG12mutation status as potential biomarker of outcome of FTD/TPI treatment in mCRC.a, Dot plot showing the associations

Updated on: December 25,2023

Genetic test could guide use of cancer chemotherapy

by Ellie Cawthera,Imperial College LondonDiscovery ofKRASG12mutation status as potential biomarker of outcome of FTD/TPI treatment in mCRC.a, Dot plot showing the associations

Updated on:December 25,2023

Radiation therapy outcomes better for African-American than Caucasian prostate cancer patients

byAmerican Society for Radiation OncologyWhile popular beliefs and population data suggest that African-American men are at higher risk of dying from prostate cancer than Caucasian men, a new an

Updated on: December 18,2023

Radiation therapy outcomes better for African-American than Caucasian prostate cancer patients

byAmerican Society for Radiation OncologyWhile popular beliefs and population data suggest that African-American men are at higher risk of dying from prostate cancer than Caucasian men, a new an

Updated on:December 18,2023

Harms reporting is inconsistent across organ cancer guidelines

byAmerican College of PhysiciansCredit: CC0 Public DomainA review of 33 organ-specific cancer screening guidelines has found that the reporting of harms related to screening tests and procedures

Updated on: December 22,2023

Harms reporting is inconsistent across organ cancer guidelines

byAmerican College of PhysiciansCredit: CC0 Public DomainA review of 33 organ-specific cancer screening guidelines has found that the reporting of harms related to screening tests and procedures

Updated on:December 22,2023

3D genome features point to possible therapeutic target for aggressive and deadly pediatric brain tumors

by Fabienne Landry,McGill University Health CentreCredit:Cell(2024). DOI: 10.1016/j.cell.2024.06.023Posterior fossa group A (PFA) ependymoma are rare, treatment-resistant pediatric t

Updated on: July 11,2024

3D genome features point to possible therapeutic target for aggressive and deadly pediatric brain tumors

by Fabienne Landry,McGill University Health CentreCredit:Cell(2024). DOI: 10.1016/j.cell.2024.06.023Posterior fossa group A (PFA) ependymoma are rare, treatment-resistant pediatric t

Updated on:July 11,2024

Jumping genes for early detection of gastric cancer

by Braulio Valdebenito-MaturanaExample of a transposable element following cancer development on spatially resolved data. In green the normal epithelium, in brown the serrated lesion, and in red the t

Updated on: December 02,2024

Jumping genes for early detection of gastric cancer

by Braulio Valdebenito-MaturanaExample of a transposable element following cancer development on spatially resolved data. In green the normal epithelium, in brown the serrated lesion, and in red the t

Updated on:December 02,2024

Testing hundreds of therapeutics outside the body to predict their effectiveness against multiple myeloma

by Peter Rüegg,ETH ZurichBone-marrow cells of a multiple myeloma patient. Red cells are healthy monocytes, green and yellow are plasma cells. Credit: Berend Snijder Lab / ETH ZurichMultiple myel

Updated on: February 20,2024

Testing hundreds of therapeutics outside the body to predict their effectiveness against multiple myeloma

by Peter Rüegg,ETH ZurichBone-marrow cells of a multiple myeloma patient. Red cells are healthy monocytes, green and yellow are plasma cells. Credit: Berend Snijder Lab / ETH ZurichMultiple myel

Updated on:February 20,2024

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha

Updated on: March 27,2024

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha

Updated on:March 27,2024

The obesity paradox in lung cancer diagnosis may differ by race

by Makhari Dysart,Thomas Jefferson UniversityCredit: Pixabay/CC0 Public DomainLung cancer is the leading cause of cancer death in the U.S., making up 25% of cancer deaths. With obesity rates sim

Updated on: December 22,2023

The obesity paradox in lung cancer diagnosis may differ by race

by Makhari Dysart,Thomas Jefferson UniversityCredit: Pixabay/CC0 Public DomainLung cancer is the leading cause of cancer death in the U.S., making up 25% of cancer deaths. With obesity rates sim

Updated on:December 22,2023