Targeting RIP3 inhibits osteoarthritis development by restoring anabolic-catabolic balance in the bone-cartilage unit

byScience China PressRIP3 plays a pivotal role in the pathogenesis of OA by disrupting cartilage extracellular matrix (ECM) metabolism homeostasis, inhibiting bone formation, and enhancing bone

Updated on: July 08,2024 0

Targeting RIP3 inhibits osteoarthritis development by restoring anabolic-catabolic balance in the bone-cartilage unit

byScience China PressRIP3 plays a pivotal role in the pathogenesis of OA by disrupting cartilage extracellular matrix (ECM) metabolism homeostasis, inhibiting bone formation, and enhancing bone

Updated on:July 08,2024 0

Multiple myeloma: New insights into early detection of aggressive tumors

byCharité - Universitätsmedizin BerlinIdentification of UBE2Q1 as a candidate protein for the aggressive phenotype of MM with gain/amp of chromosome 1q. Credit:Nature Cancer(2024). D

Updated on: July 08,2024 0

Multiple myeloma: New insights into early detection of aggressive tumors

byCharité - Universitätsmedizin BerlinIdentification of UBE2Q1 as a candidate protein for the aggressive phenotype of MM with gain/amp of chromosome 1q. Credit:Nature Cancer(2024). D

Updated on:July 08,2024 0

A prosthesis driven by the nervous system helps people with amputation walk naturally

by Anne Trafton,Massachusetts Institute of TechnologyNeuroprosthesis. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-02994-9State-of-the-art prosthetic limbs can help people w

Updated on: July 08,2024 0

A prosthesis driven by the nervous system helps people with amputation walk naturally

by Anne Trafton,Massachusetts Institute of TechnologyNeuroprosthesis. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-02994-9State-of-the-art prosthetic limbs can help people w

Updated on:July 08,2024 0

Novel mechanism for targeting bone marrow adipocytes to prevent bone loss

by Shenzhen Institute of Advanced Technology, Chinese Academy of SciencesSchematic diagram showing adipocyte ESRRA deficiency preserves osteogenesis and vascular formation in adipocyte-rich bone marrow

Updated on: July 08,2024 0

Novel mechanism for targeting bone marrow adipocytes to prevent bone loss

by Shenzhen Institute of Advanced Technology, Chinese Academy of SciencesSchematic diagram showing adipocyte ESRRA deficiency preserves osteogenesis and vascular formation in adipocyte-rich bone marrow

Updated on:July 08,2024 0

New gene linked to osteoporosis identified

New gene linked to osteoporosis identifiedbyOsaka UniversityMolecular mechanism of senescence induced by osteoblast MEN1 deficiency SASP: senescence-associated secretory phenotype. Credit:

Updated on: July 08,2024 0

New gene linked to osteoporosis identified

New gene linked to osteoporosis identifiedbyOsaka UniversityMolecular mechanism of senescence induced by osteoblast MEN1 deficiency SASP: senescence-associated secretory phenotype. Credit:

Updated on:July 08,2024 0

Can A.I. tell you if you have osteoporosis? Newly developed deep learning model shows promise

byTulane UniversityAUC comparison among different models. (A) AUC comparison among different models with different sample sizes; (B) AUC comparison among different models with different numbers

Updated on: July 08,2024 0

Can A.I. tell you if you have osteoporosis? Newly developed deep learning model shows promise

byTulane UniversityAUC comparison among different models. (A) AUC comparison among different models with different sample sizes; (B) AUC comparison among different models with different numbers

Updated on:July 08,2024 0

Complement modulators for osteoarthritis

Osteoarthritis (OA), also known as degenerative joint disease, is mainly characterized by abnormal proliferation of cartilage at the joint margins and cartilage detachment. Clinical manifestations include chronic joint pain, swelling, and friction sounds

Updated on: July 06,2024 0

Complement modulators for osteoarthritis

Osteoarthritis (OA), also known as degenerative joint disease, is mainly characterized by abnormal proliferation of cartilage at the joint margins and cartilage detachment. Clinical manifestations include chronic joint pain, swelling, and friction sounds

Updated on:July 06,2024 0

Walking or running: For the same distance, which consumes more energy?

by Clément Lemineur, Clément Naveilhan and François Dernoncourt,The ConversationCredit: Pixabay/CC0 Public DomainIt's Monday morning, the alarm goes off and it's already 7:30 a.m.—and yo

Updated on: July 06,2024 0

Walking or running: For the same distance, which consumes more energy?

by Clément Lemineur, Clément Naveilhan and François Dernoncourt,The ConversationCredit: Pixabay/CC0 Public DomainIt's Monday morning, the alarm goes off and it's already 7:30 a.m.—and yo

Updated on:July 06,2024 0

Osteoblast-derived extracellular vesicles exert bone formation effects by WIF1-mediated regulation of mitophagy: Study

byScience China PressWif1 overexpression accelerated osteogenic differentiation by activating genes related to late-stage osteogenic differentiation and mitophagy processes. Moreover administeri

Updated on: July 06,2024 0

Osteoblast-derived extracellular vesicles exert bone formation effects by WIF1-mediated regulation of mitophagy: Study

byScience China PressWif1 overexpression accelerated osteogenic differentiation by activating genes related to late-stage osteogenic differentiation and mitophagy processes. Moreover administeri

Updated on:July 06,2024 0

Tips to staying germ-free at the gym

by Robin FosterGoing to the gym is good for your overall health, but if you and the gym aren't practicing good hygiene you could still catch a nasty illness, an expert says."Good hygiene prev

Updated on: July 05,2024 0

Tips to staying germ-free at the gym

by Robin FosterGoing to the gym is good for your overall health, but if you and the gym aren't practicing good hygiene you could still catch a nasty illness, an expert says."Good hygiene prev

Updated on:July 05,2024 0

Too much treadmill? This could help your shin splints

byUniversity of VirginiaCredit: Pixabay/CC0 Public DomainGood news for all the treadmill runners who suffer from stubborn and painful shin splints: A little outdoor gait training may help, new r

Updated on: July 05,2024 0

Too much treadmill? This could help your shin splints

byUniversity of VirginiaCredit: Pixabay/CC0 Public DomainGood news for all the treadmill runners who suffer from stubborn and painful shin splints: A little outdoor gait training may help, new r

Updated on:July 05,2024 0

Outcomes better at one year with physical therapy for knee OA

(HealthDay)—For patients with osteoarthritis of the knee, those undergoing physical therapy have less pain and functional disability at one year compared with those who receive an intraarticular gluco

Updated on: July 04,2024 3

Outcomes better at one year with physical therapy for knee OA

(HealthDay)—For patients with osteoarthritis of the knee, those undergoing physical therapy have less pain and functional disability at one year compared with those who receive an intraarticular gluco

Updated on:July 04,2024 3