New web portal empowers drug discovery, systems-level analysis of critical kinase-substrate interactions

byThe Mount Sinai HospitalKiNet functionalities. Credit:npj Systems Biology and Applications(2024). DOI: 10.1038/s41540-024-00442-5Researchers from the Icahn School of Medicine at Mo

Updated on: October 21,2024

New web portal empowers drug discovery, systems-level analysis of critical kinase-substrate interactions

byThe Mount Sinai HospitalKiNet functionalities. Credit:npj Systems Biology and Applications(2024). DOI: 10.1038/s41540-024-00442-5Researchers from the Icahn School of Medicine at Mo

Updated on:October 21,2024

SGLT-2 inhibitors show mixed results after heart attack

byAmerican College of CardiologyCredit: Unsplash/CC0 Public DomainWhile the composite of death and heart failure hospitalizations was not significantly reduced, empagliflozin may help reduce hea

Updated on: April 28,2024

SGLT-2 inhibitors show mixed results after heart attack

byAmerican College of CardiologyCredit: Unsplash/CC0 Public DomainWhile the composite of death and heart failure hospitalizations was not significantly reduced, empagliflozin may help reduce hea

Updated on:April 28,2024

Evaluating selpercatinib for the treatment of non-small cell lung cancer

by D'Or Institute for Research and EducationCredit: Unsplash/CC0 Public DomainA phase III LIBRETTO-431 multicenter study has evaluated the efficacy and safety of selpercatinib compared to control

Updated on: January 26,2024

Evaluating selpercatinib for the treatment of non-small cell lung cancer

by D'Or Institute for Research and EducationCredit: Unsplash/CC0 Public DomainA phase III LIBRETTO-431 multicenter study has evaluated the efficacy and safety of selpercatinib compared to control

Updated on:January 26,2024

New wearable patch measures trace perspiration during activity and rest

byUniversity of TsukubaConceptual illustration portrays fully assembled patch securely affixed to skin's surface. Credit:Advanced Science(2024). DOI: 10.1002/advs.202401947Resear

Updated on: July 05,2024

New wearable patch measures trace perspiration during activity and rest

byUniversity of TsukubaConceptual illustration portrays fully assembled patch securely affixed to skin's surface. Credit:Advanced Science(2024). DOI: 10.1002/advs.202401947Resear

Updated on:July 05,2024

The genomic architecture of inherited DNA variants

by Graciela Gutierrez,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainYou have your mother's eyes and your father's smile, but genetics is much more than just what's on th

Updated on: March 27,2024

The genomic architecture of inherited DNA variants

by Graciela Gutierrez,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainYou have your mother's eyes and your father's smile, but genetics is much more than just what's on th

Updated on:March 27,2024

Pharmacologic restraint used in 3 percent of pediatric mental health admissions

by Elana GotkineThe use of pharmacologic restraints occurs in 3 percent of hospitalizations for children admitted with a primary mental health diagnosis, according to a study published online Dec. 11

Updated on: January 26,2024

Pharmacologic restraint used in 3 percent of pediatric mental health admissions

by Elana GotkineThe use of pharmacologic restraints occurs in 3 percent of hospitalizations for children admitted with a primary mental health diagnosis, according to a study published online Dec. 11

Updated on:January 26,2024

The year in opioid settlements: 5 things you need to know

DECEMBER 30, 2023 Editors' notesby Aneri Pattani, KFF Health NewsCredit: Pixabay/CC0 Public DomainThis year, about $1.5 billion has landed in state and local government coffers from court settleme

Updated on: March 15,2024

The year in opioid settlements: 5 things you need to know

DECEMBER 30, 2023 Editors' notesby Aneri Pattani, KFF Health NewsCredit: Pixabay/CC0 Public DomainThis year, about $1.5 billion has landed in state and local government coffers from court settleme

Updated on:March 15,2024

Study of palliative care demonstrates scalable strategy to increase support for seriously ill patients in hospital

JANUARY 16, 2024byPerelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainOrdering a palliative care consultation by "default"—via an automatic o

Updated on: March 15,2024

Study of palliative care demonstrates scalable strategy to increase support for seriously ill patients in hospital

JANUARY 16, 2024byPerelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainOrdering a palliative care consultation by "default"—via an automatic o

Updated on:March 15,2024

Re-engineered antibiotic shows potential for treatment of drug-resistant bacteria

by St. Jude Children's Research HospitalResearchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness ag

Updated on: March 06,2024

Re-engineered antibiotic shows potential for treatment of drug-resistant bacteria

by St. Jude Children's Research HospitalResearchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness ag

Updated on:March 06,2024

A computational model to simulate the biomechanical growth of breast tumors

byCarlos III University of MadridTumor cells invading surrounding tissue under different mechanical conditions. The blue line indicates the boundary of the solid tumor and the yellow line indica

Updated on: March 28,2024

A computational model to simulate the biomechanical growth of breast tumors

byCarlos III University of MadridTumor cells invading surrounding tissue under different mechanical conditions. The blue line indicates the boundary of the solid tumor and the yellow line indica

Updated on:March 28,2024

Spot-on laser treatment for skin blemishes becoming clearer with new index

by Osaka Metropolitan UniversityLeft: Unirradiated melanosomes show a smooth surface. Right: Irradiation by picosecond lasers with a pulse width of 450 ps at a wavelength of 1,064 nm and a fluenc

Updated on: March 30,2024

Spot-on laser treatment for skin blemishes becoming clearer with new index

by Osaka Metropolitan UniversityLeft: Unirradiated melanosomes show a smooth surface. Right: Irradiation by picosecond lasers with a pulse width of 450 ps at a wavelength of 1,064 nm and a fluenc

Updated on:March 30,2024

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Updated on: July 23,2024

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Updated on:July 23,2024