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Breakthroughs
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Tryptophan in diet and gut bacteria protect against E. coli infection, study shows

Tryptophan in diet and gut bacteria protect against E. coli infection, study shows

by Krishna Ramanujan,Cornell UniversityDietary Trp protects against infection with C. rodentium strain DBS100 in a mouse model of EHEC infection. Credit:Nature(2024). DOI: 10.1038/s4

Tryptophan in diet and gut bacteria protect against E. coli infection, study shows

by Krishna Ramanujan,Cornell UniversityDietary Trp protects against infection with C. rodentium strain DBS100 in a mouse model of EHEC infection. Credit:Nature(2024). DOI: 10.1038/s4
Poor trial results may prompt maker to pull ALS drug from market

Poor trial results may prompt maker to pull ALS drug from market

by Robin FosterFollowing disappointing trial results, the maker of a controversial ALS drug may pull the medication off the market.In astatementissued Friday, Amylyx Pharmaceuticals said t

Poor trial results may prompt maker to pull ALS drug from market

by Robin FosterFollowing disappointing trial results, the maker of a controversial ALS drug may pull the medication off the market.In astatementissued Friday, Amylyx Pharmaceuticals said t
Researchers shed light on the molecular causes of different functions of opioid receptors

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti
Wastewater sequencing reveals community and variant dynamics of the collective human virome

Wastewater sequencing reveals community and variant dynamics of the collective human virome

by Ana María S. Rodríguez,Baylor College of MedicineStudy sites, capture, and viral diversity. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-42064-1In the not-so-distan

Wastewater sequencing reveals community and variant dynamics of the collective human virome

by Ana María S. Rodríguez,Baylor College of MedicineStudy sites, capture, and viral diversity. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-42064-1In the not-so-distan
Vosoritide beneficial for children younger than 5 years with achondroplasia

Vosoritide beneficial for children younger than 5 years with achondroplasia

by Elana GotkineFor children with achondroplasia, vosoritide is associated with a gain in the change in height Z score from baseline and a mild adverse event profile, according to a study published in

Vosoritide beneficial for children younger than 5 years with achondroplasia

by Elana GotkineFor children with achondroplasia, vosoritide is associated with a gain in the change in height Z score from baseline and a mild adverse event profile, according to a study published in
Study reveals insights into diabetic kidney disease and how anti-obesity drugs work

Study reveals insights into diabetic kidney disease and how anti-obesity drugs work

by Monash UniversityThis image shows a cross section of a kidney. Credit: Holly Fischer/WikipediaData from Australian researchers could partly explain why a trial of a new drug for diabetes, was

Study reveals insights into diabetic kidney disease and how anti-obesity drugs work

by Monash UniversityThis image shows a cross section of a kidney. Credit: Holly Fischer/WikipediaData from Australian researchers could partly explain why a trial of a new drug for diabetes, was
Research finds T cell subset significantly expands in spleen and brain after virus infection

Research finds T cell subset significantly expands in spleen and brain after virus infection

byScience China Pressslc43a2+T cells differentiate and mature in spleen and are then transported to brain to trigger the production of cytokines involved in antiviral strategies against RG

Research finds T cell subset significantly expands in spleen and brain after virus infection

byScience China Pressslc43a2+T cells differentiate and mature in spleen and are then transported to brain to trigger the production of cytokines involved in antiviral strategies against RG
Dapagliflozin cuts cardiovascular events in patients with heart failure, T2D

Dapagliflozin cuts cardiovascular events in patients with heart failure, T2D

by Elana GotkineFor patients with heart failure and type 2 diabetes (T2D), dapagliflozin does not reduce urinary albumin-to-creatinine ratio (UACR) but does reduce some cardiovascular events, accordin

Dapagliflozin cuts cardiovascular events in patients with heart failure, T2D

by Elana GotkineFor patients with heart failure and type 2 diabetes (T2D), dapagliflozin does not reduce urinary albumin-to-creatinine ratio (UACR) but does reduce some cardiovascular events, accordin
Research explores liberalization of medical marijuana and mental health in the US

Research explores liberalization of medical marijuana and mental health in the US

by University of BaselRegulation of (medical) marijuana across US states at the end of 2018. Credit:Health Economics, Policy and Law(2024). DOI: 10.1017/S1744133124000033The approval

Research explores liberalization of medical marijuana and mental health in the US

by University of BaselRegulation of (medical) marijuana across US states at the end of 2018. Credit:Health Economics, Policy and Law(2024). DOI: 10.1017/S1744133124000033The approval
A new weapon against the super-tough C diff bacteria tested in phase-one human trial

A new weapon against the super-tough C diff bacteria tested in phase-one human trial

by Laurie Fickman,University of HoustonFecal drug concentrations of omadacycline and vancomycin. Credit:The Journal of Infectious Diseases(2023). DOI: 10.1093/infdis/jiad537In a phas

A new weapon against the super-tough C diff bacteria tested in phase-one human trial

by Laurie Fickman,University of HoustonFecal drug concentrations of omadacycline and vancomycin. Credit:The Journal of Infectious Diseases(2023). DOI: 10.1093/infdis/jiad537In a phas