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The dual role of well-known protein sheds light on Parkinson's disease mechanisms

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th
Experimental compound extends life in amyotrophic lateral sclerosis mouse model

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i
Erections: What researchers learned from mice could help with sexual health in humans

Erections: What researchers learned from mice could help with sexual health in humans

FEBRUARY 9, 2024 Editors' notesby Christian Göritz,The ConversationFibroblasts mediate erectile activity–dependent modulation of penile blood flow. Credit:Science(2024). DOI: 10.

Erections: What researchers learned from mice could help with sexual health in humans

FEBRUARY 9, 2024 Editors' notesby Christian Göritz,The ConversationFibroblasts mediate erectile activity–dependent modulation of penile blood flow. Credit:Science(2024). DOI: 10.
Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

by Bob Yirka , Medical XpressExome-wide, gene-based association testing in 38,043 left-handed and 313,271 right-handed individuals, based on rare protein-altering variants. Top: the strict variant set

Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

by Bob Yirka , Medical XpressExome-wide, gene-based association testing in 38,043 left-handed and 313,271 right-handed individuals, based on rare protein-altering variants. Top: the strict variant set
Researchers identify peptides produced by the proteasome that degrade damaged proteins

Researchers identify peptides produced by the proteasome that degrade damaged proteins

FEBRUARY 14, 2024by Carmen Rotte,Max Planck SocietyUsing innovative computer programs and biochemical experiments, researchers identified and quantified fragments that the cellular garbage dispo

Researchers identify peptides produced by the proteasome that degrade damaged proteins

FEBRUARY 14, 2024by Carmen Rotte,Max Planck SocietyUsing innovative computer programs and biochemical experiments, researchers identified and quantified fragments that the cellular garbage dispo
Urine test halves painful procedures in bladder cancer follow up, new trial shows

Urine test halves painful procedures in bladder cancer follow up, new trial shows

by European Association of UrologyCredit: Unsplash/CC0 Public DomainA simple urine test can more than halve the number of cystoscopies necessary to follow up high-risk bladder cancer patients, ne

Urine test halves painful procedures in bladder cancer follow up, new trial shows

by European Association of UrologyCredit: Unsplash/CC0 Public DomainA simple urine test can more than halve the number of cystoscopies necessary to follow up high-risk bladder cancer patients, ne
New monoclonal antibody for treating cerebral ischemia injury

New monoclonal antibody for treating cerebral ischemia injury

FEBRUARY 27, 2024byThe University of Hong KongProfessor Ruby Hoo Lai-chong (first, right), Department of Pharmacology and Pharmacy of HKUMed, and her research team have successfully developed a

New monoclonal antibody for treating cerebral ischemia injury

FEBRUARY 27, 2024byThe University of Hong KongProfessor Ruby Hoo Lai-chong (first, right), Department of Pharmacology and Pharmacy of HKUMed, and her research team have successfully developed a
The roles of genes and 3D genome folds in determining health

The roles of genes and 3D genome folds in determining health

by Carmen Rotte,Max Planck SocietyModel for the mechanism of chromatin domain formation in S. cerevisiae. Credit:Nature Genetics(2024). DOI:10.1038/s41588-023-01649-8Whether we stay

The roles of genes and 3D genome folds in determining health

by Carmen Rotte,Max Planck SocietyModel for the mechanism of chromatin domain formation in S. cerevisiae. Credit:Nature Genetics(2024). DOI:10.1038/s41588-023-01649-8Whether we stay
Novel compound protects against infection by virus that causes COVID-19, preliminary studies show

Novel compound protects against infection by virus that causes COVID-19, preliminary studies show

JANUARY 5, 2024 Editors' notesbyDana-Farber Cancer InstituteDesign and screening of stapled lipopeptide inhibitors of SARS-CoV-2.aSchematic of the six-helix bundle (6-HB) fusion

Novel compound protects against infection by virus that causes COVID-19, preliminary studies show

JANUARY 5, 2024 Editors' notesbyDana-Farber Cancer InstituteDesign and screening of stapled lipopeptide inhibitors of SARS-CoV-2.aSchematic of the six-helix bundle (6-HB) fusion
Smarter blood tests could deliver faster diagnoses and improved outcomes

Smarter blood tests could deliver faster diagnoses and improved outcomes

by Dalin Clark,Michigan State UniversitySmall molecule modulation of protein corona significantly enhances deep plasma proteome profiling. Credit: Mahmoudi GroupMedical professionals have long k

Smarter blood tests could deliver faster diagnoses and improved outcomes

by Dalin Clark,Michigan State UniversitySmall molecule modulation of protein corona significantly enhances deep plasma proteome profiling. Credit: Mahmoudi GroupMedical professionals have long k
Team develops a single-nucleus resolution atlas of white adipose tissue in different depots

Team develops a single-nucleus resolution atlas of white adipose tissue in different depots

FEBRUARY 5, 2024by Higher Education PressWorkflow to perform snRNA-seq of different WAT depots. The nuclei were derived from subcutaneous (S), epididymal (E), mesenteric (M), peri-nephritic (N), and p

Team develops a single-nucleus resolution atlas of white adipose tissue in different depots

FEBRUARY 5, 2024by Higher Education PressWorkflow to perform snRNA-seq of different WAT depots. The nuclei were derived from subcutaneous (S), epididymal (E), mesenteric (M), peri-nephritic (N), and p
New methodological approach allows more precise summary of study results

New methodological approach allows more precise summary of study results

JANUARY 24, 2024byInstitute for Quality and Efficiency in Health CareCredit: Pixabay/CC0 Public DomainBefore new drugs are launched on the market they are tested in clinical studies in which one

New methodological approach allows more precise summary of study results

JANUARY 24, 2024byInstitute for Quality and Efficiency in Health CareCredit: Pixabay/CC0 Public DomainBefore new drugs are launched on the market they are tested in clinical studies in which one