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Hematology&Oncology
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Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi
Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatmentsby Nik Papageorgiou,Ecole Polytechnique Federale de LausanneLymphomoid spiral. Credit: Albert Santamaria-MartinezScientists at EP

Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatmentsby Nik Papageorgiou,Ecole Polytechnique Federale de LausanneLymphomoid spiral. Credit: Albert Santamaria-MartinezScientists at EP
Overcoming glioblastoma resistance to chemotherapy

Overcoming glioblastoma resistance to chemotherapy

byInstitute for Basic ScienceThe "onion model" illustrates how the one-by-one inactivation of the DNA repair pathways brings about changes in TMZ-induced mutational signatures. Every &

Overcoming glioblastoma resistance to chemotherapy

byInstitute for Basic ScienceThe "onion model" illustrates how the one-by-one inactivation of the DNA repair pathways brings about changes in TMZ-induced mutational signatures. Every &
Novel oncolytic immunotherapy shows promise for patients with bladder cancer

Novel oncolytic immunotherapy shows promise for patients with bladder cancer

byMayo ClinicCredit: AI-generated imageA Mayo Clinic Comprehensive Cancer Center researcher will share findings from a late-breaking abstract at the2024 Society of Urologic Oncology Annual

Novel oncolytic immunotherapy shows promise for patients with bladder cancer

byMayo ClinicCredit: AI-generated imageA Mayo Clinic Comprehensive Cancer Center researcher will share findings from a late-breaking abstract at the2024 Society of Urologic Oncology Annual
Low-dose plasma treatment shows promise for slowing down tumor growth

Low-dose plasma treatment shows promise for slowing down tumor growth

by Nie Lili and Zhao Weiwei,Chinese Academy of SciencesUnder the influence of electrodes, low-temperature plasma emits a purple glow in the laboratory. Credit: Nie LiliA recent study has shown t

Low-dose plasma treatment shows promise for slowing down tumor growth

by Nie Lili and Zhao Weiwei,Chinese Academy of SciencesUnder the influence of electrodes, low-temperature plasma emits a purple glow in the laboratory. Credit: Nie LiliA recent study has shown t
Even low levels of arsenic in drinking water raise kidney cancer risk, new study finds

Even low levels of arsenic in drinking water raise kidney cancer risk, new study finds

by Ann Kellett,Texas A&M UniversityCredit: Unsplash/CC0 Public DomainNew research findings from the Texas A&M University School of Public Health indicate that exposure to even low levels

Even low levels of arsenic in drinking water raise kidney cancer risk, new study finds

by Ann Kellett,Texas A&M UniversityCredit: Unsplash/CC0 Public DomainNew research findings from the Texas A&M University School of Public Health indicate that exposure to even low levels
Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

byThe Mount Sinai HospitalLurbinectedin augments the anti-tumor immune response of PD-L1 blockade in immunocompetent SCLC models. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.x

Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

byThe Mount Sinai HospitalLurbinectedin augments the anti-tumor immune response of PD-L1 blockade in immunocompetent SCLC models. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.x
Putting the brakes on prostate cancer cells: Androgen receptor can alter normal prostate growth

Putting the brakes on prostate cancer cells: Androgen receptor can alter normal prostate growth

by Alan Dove,Cornell UniversityA clump of prostate cancer cells. The blue-green cells are growing, whereas the pink ones are dying by programmed cell death (apoptosis). Credit: Dave McCarthy and

Putting the brakes on prostate cancer cells: Androgen receptor can alter normal prostate growth

by Alan Dove,Cornell UniversityA clump of prostate cancer cells. The blue-green cells are growing, whereas the pink ones are dying by programmed cell death (apoptosis). Credit: Dave McCarthy and
Menopausal status influences long-term benefit from anti-hormonal treatment, study shows

Menopausal status influences long-term benefit from anti-hormonal treatment, study shows

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainToday, women with estrogen-sensitive breast cancer receive anti-hormonal therapy. Researchers now show that postmenopausal women with low

Menopausal status influences long-term benefit from anti-hormonal treatment, study shows

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainToday, women with estrogen-sensitive breast cancer receive anti-hormonal therapy. Researchers now show that postmenopausal women with low
Microscopic cell changes linked to cancer's rapid growth in stiff tissues

Microscopic cell changes linked to cancer's rapid growth in stiff tissues

by Bailey Noah,Texas A&M UniversityResearchers in the Lele Lab analyzing cell imaging data. Credit: Texas A&M EngineeringIn 2022 alone, over 20 million people were diagnosed with cancer,

Microscopic cell changes linked to cancer's rapid growth in stiff tissues

by Bailey Noah,Texas A&M UniversityResearchers in the Lele Lab analyzing cell imaging data. Credit: Texas A&M EngineeringIn 2022 alone, over 20 million people were diagnosed with cancer,