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Hematology&Oncology
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CRISPR study silences gene mutations that drive aggressive cancers

CRISPR study silences gene mutations that drive aggressive cancers

byPeter MacCallum Cancer CentreMolecular principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision. Credit:Scienc

CRISPR study silences gene mutations that drive aggressive cancers

byPeter MacCallum Cancer CentreMolecular principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision. Credit:Scienc
Researchers map genetic variants associated with pancreatic cancer in Brazilian patients

Researchers map genetic variants associated with pancreatic cancer in Brazilian patients

Researchers map genetic variants associated with pancreatic cancer in Brazilian patientsby Karina Ninni,FAPESPSolar explosion graph depicting spectrum of PGVs and VUSs in pancreatic cancer patie

Researchers map genetic variants associated with pancreatic cancer in Brazilian patients

Researchers map genetic variants associated with pancreatic cancer in Brazilian patientsby Karina Ninni,FAPESPSolar explosion graph depicting spectrum of PGVs and VUSs in pancreatic cancer patie
Coffee and tea linked to lower head and neck cancer risk

Coffee and tea linked to lower head and neck cancer risk

byWileyCredit: Pixabay/CC0 Public DomainIn an analysis of data from more than a dozen studies, coffee and tea consumption was linked with lower risks of developing head and neck cancer, includin

Coffee and tea linked to lower head and neck cancer risk

byWileyCredit: Pixabay/CC0 Public DomainIn an analysis of data from more than a dozen studies, coffee and tea consumption was linked with lower risks of developing head and neck cancer, includin
Low-dose plasma treatment shows promise for slowing down tumor growth

Low-dose plasma treatment shows promise for slowing down tumor growth

by Nie Lili and Zhao Weiwei,Chinese Academy of SciencesUnder the influence of electrodes, low-temperature plasma emits a purple glow in the laboratory. Credit: Nie LiliA recent study has shown t

Low-dose plasma treatment shows promise for slowing down tumor growth

by Nie Lili and Zhao Weiwei,Chinese Academy of SciencesUnder the influence of electrodes, low-temperature plasma emits a purple glow in the laboratory. Credit: Nie LiliA recent study has shown t
Molecular 'ZIP code' draws killer T cells to brain tumors

Molecular 'ZIP code' draws killer T cells to brain tumors

by Levi Gadye,University of California, San FranciscoProgramming tissue-sensing T cells to deliver therapeutics to the brain. Credit:Science(2024). DOI: 10.1126/science.adl4237UCSF s

Molecular 'ZIP code' draws killer T cells to brain tumors

by Levi Gadye,University of California, San FranciscoProgramming tissue-sensing T cells to deliver therapeutics to the brain. Credit:Science(2024). DOI: 10.1126/science.adl4237UCSF s
PIVKA-II-based model IDs liver cancer risk in hep C-related cirrhosis

PIVKA-II-based model IDs liver cancer risk in hep C-related cirrhosis

by Elana GotkineAmong patients with hepatitis C virus (HCV)-related cirrhosis with sustained virological response (SVR) to direct-acting antivirals (DAAs), a serum protein induced by vitamin K absence

PIVKA-II-based model IDs liver cancer risk in hep C-related cirrhosis

by Elana GotkineAmong patients with hepatitis C virus (HCV)-related cirrhosis with sustained virological response (SVR) to direct-acting antivirals (DAAs), a serum protein induced by vitamin K absence
Fibroblastic reticula cells can organize T cells in the fight against lung cancer

Fibroblastic reticula cells can organize T cells in the fight against lung cancer

by Justin Jackson , Medical XpressGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.10.042Institute of Immunobiology-led research has made a significant breakthrough in under

Fibroblastic reticula cells can organize T cells in the fight against lung cancer

by Justin Jackson , Medical XpressGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.10.042Institute of Immunobiology-led research has made a significant breakthrough in under
Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi
Machine learning uncovers three osteosarcoma subtypes for targeted treatment

Machine learning uncovers three osteosarcoma subtypes for targeted treatment

byUniversity of East AngliaLatent process decomposition model optimization, subtype assignment and clinical outcome. Credit:Briefings in Bioinformatics(2024). DOI: 10.1093/bib/bbae66

Machine learning uncovers three osteosarcoma subtypes for targeted treatment

byUniversity of East AngliaLatent process decomposition model optimization, subtype assignment and clinical outcome. Credit:Briefings in Bioinformatics(2024). DOI: 10.1093/bib/bbae66
Oncologist discusses treating liver cancer

Oncologist discusses treating liver cancer

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainLiver cancer rates have more than tripled in the U.S. since 1980 and continue to rise. More than 41,000 people will be diagnosed with liver

Oncologist discusses treating liver cancer

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainLiver cancer rates have more than tripled in the U.S. since 1980 and continue to rise. More than 41,000 people will be diagnosed with liver
Possible colon cancer vaccine target uncovered in bacteria

Possible colon cancer vaccine target uncovered in bacteria

byWellcome Trust Sanger InstituteEscherichia coli. Credit: Rocky Mountain Laboratories, NIAID, NIHHigher rates of certain cancers in countries, such as the UK, may be linked to two particular st

Possible colon cancer vaccine target uncovered in bacteria

byWellcome Trust Sanger InstituteEscherichia coli. Credit: Rocky Mountain Laboratories, NIAID, NIHHigher rates of certain cancers in countries, such as the UK, may be linked to two particular st