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Hematology&Oncology
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Anticancer drugs could make immunotherapies more effective

Anticancer drugs could make immunotherapies more effective

byWeill Cornell Medical CollegePretreatment with EZH2 inhibitor (top right) leads to higher recruitment of CAR-T cells (red) into the lymph node tumor compared with control (top left). Pretreatm

Anticancer drugs could make immunotherapies more effective

byWeill Cornell Medical CollegePretreatment with EZH2 inhibitor (top right) leads to higher recruitment of CAR-T cells (red) into the lymph node tumor compared with control (top left). Pretreatm
Engineered CAR-NK cells offer an alternative approach to fighting leukemia

Engineered CAR-NK cells offer an alternative approach to fighting leukemia

Engineered CAR-NK cells offer an alternative approach to fighting leukemiaby Markus Bernards,Goethe University Frankfurt am MainGeneration process and evaluation of CRISPR/Cas9 knockout for CAR3

Engineered CAR-NK cells offer an alternative approach to fighting leukemia

Engineered CAR-NK cells offer an alternative approach to fighting leukemiaby Markus Bernards,Goethe University Frankfurt am MainGeneration process and evaluation of CRISPR/Cas9 knockout for CAR3
Immunosuppression study helps understand why some prostate cancer treatments do not work as expected

Immunosuppression study helps understand why some prostate cancer treatments do not work as expected

byTampere UniversityOn the left is a tissue sample from the prostate stained with hematoxylin and eosin. Hematoxylin stains the nuclei blue or purple because it binds to DNA, and eosin stains th

Immunosuppression study helps understand why some prostate cancer treatments do not work as expected

byTampere UniversityOn the left is a tissue sample from the prostate stained with hematoxylin and eosin. Hematoxylin stains the nuclei blue or purple because it binds to DNA, and eosin stains th
Neurocognitive battery feasible in 3-year-olds during leukemia treatment

Neurocognitive battery feasible in 3-year-olds during leukemia treatment

by Elana GotkineA brief neurocognitive battery is feasible for use in 3-year-olds during acute lymphoblastic leukemia treatment, according to a studypublishedonline Dec. 9 inPediatri

Neurocognitive battery feasible in 3-year-olds during leukemia treatment

by Elana GotkineA brief neurocognitive battery is feasible for use in 3-year-olds during acute lymphoblastic leukemia treatment, according to a studypublishedonline Dec. 9 inPediatri
Low-dose plasma treatment shows promise for slowing down tumor growth

Low-dose plasma treatment shows promise for slowing down tumor growth

by Nie Lili and Zhao Weiwei,Chinese Academy of SciencesUnder the influence of electrodes, low-temperature plasma emits a purple glow in the laboratory. Credit: Nie LiliA recent study has shown t

Low-dose plasma treatment shows promise for slowing down tumor growth

by Nie Lili and Zhao Weiwei,Chinese Academy of SciencesUnder the influence of electrodes, low-temperature plasma emits a purple glow in the laboratory. Credit: Nie LiliA recent study has shown t
Adding SBRT to systemic therapy could boost outcomes for some locally advanced hepatocellular carcinoma patients

Adding SBRT to systemic therapy could boost outcomes for some locally advanced hepatocellular carcinoma patients

Adding SBRT to systemic therapy could boost outcomes for some locally advanced hepatocellular carcinoma patientsby NRG OncologyCredit: Pixabay/CC0 Public DomainRecent results from the Phase III NRG-RT

Adding SBRT to systemic therapy could boost outcomes for some locally advanced hepatocellular carcinoma patients

Adding SBRT to systemic therapy could boost outcomes for some locally advanced hepatocellular carcinoma patientsby NRG OncologyCredit: Pixabay/CC0 Public DomainRecent results from the Phase III NRG-RT
How breast cancer cells survive in bone marrow after remission

How breast cancer cells survive in bone marrow after remission

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI170953A study from researchers at the University of Michigan and the Unive

How breast cancer cells survive in bone marrow after remission

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI170953A study from researchers at the University of Michigan and the Unive
Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi
Machine learning uncovers three osteosarcoma subtypes for targeted treatment

Machine learning uncovers three osteosarcoma subtypes for targeted treatment

byUniversity of East AngliaLatent process decomposition model optimization, subtype assignment and clinical outcome. Credit:Briefings in Bioinformatics(2024). DOI: 10.1093/bib/bbae66

Machine learning uncovers three osteosarcoma subtypes for targeted treatment

byUniversity of East AngliaLatent process decomposition model optimization, subtype assignment and clinical outcome. Credit:Briefings in Bioinformatics(2024). DOI: 10.1093/bib/bbae66
Researchers explore e-bikes for cancer recovery

Researchers explore e-bikes for cancer recovery

by Patty Wellborn,University of British ColumbiaOutline of the CRANK intervention development. APEASE: Acceptability, Practicability, Effectiveness, Affordability, Side-Effects, and Equity; BCT:

Researchers explore e-bikes for cancer recovery

by Patty Wellborn,University of British ColumbiaOutline of the CRANK intervention development. APEASE: Acceptability, Practicability, Effectiveness, Affordability, Side-Effects, and Equity; BCT: