C-reactive protein reduces the immune response in inflammatory disease

by Karin Söderlund Leifler,Linköping UniversityGraphical abstract. Credit:Journal of Autoimmunity(2023). DOI: 10.1016/j.jaut.2023.102998The biological function of the C-reactive prot

Updated on: April 13,2024 13

C-reactive protein reduces the immune response in inflammatory disease

by Karin Söderlund Leifler,Linköping UniversityGraphical abstract. Credit:Journal of Autoimmunity(2023). DOI: 10.1016/j.jaut.2023.102998The biological function of the C-reactive prot

Updated on:April 13,2024 13

Renal macrophages observed playing crucial role in preventing kidney stones

by Justin Jackson , Medical XpressGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.12.003Researchers at Zhejiang University School of Medicine, China, have investigate

Updated on: March 07,2024 19

Renal macrophages observed playing crucial role in preventing kidney stones

by Justin Jackson , Medical XpressGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.12.003Researchers at Zhejiang University School of Medicine, China, have investigate

Updated on:March 07,2024 19

Study uncovers novel mechanisms behind food allergies

by Melissa Rohman,Northwestern UniversityCredit:Mucosal Immunology(2023). DOI: 10.1016/j.mucimm.2023.12.001A recent Northwestern Medicine study has shed light on the mechanisms of a

Updated on: March 19,2024 18

Study uncovers novel mechanisms behind food allergies

by Melissa Rohman,Northwestern UniversityCredit:Mucosal Immunology(2023). DOI: 10.1016/j.mucimm.2023.12.001A recent Northwestern Medicine study has shed light on the mechanisms of a

Updated on:March 19,2024 18

Smoking cessation may reduce risk of rheumatoid arthritis

by Brigham and Women's HospitalCredit: CC0 Public DomainSmoking is an important risk factor for developing the most common form of rheumatoid arthritis (RA) and other inflammatory diseases, b

Updated on: May 13,2024 7

Smoking cessation may reduce risk of rheumatoid arthritis

by Brigham and Women's HospitalCredit: CC0 Public DomainSmoking is an important risk factor for developing the most common form of rheumatoid arthritis (RA) and other inflammatory diseases, b

Updated on:May 13,2024 7

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on: January 26,2024 19

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on:January 26,2024 19

New method is better able to map immune response and paves way for new treatments

byKarolinska InstitutetSpatial transcriptomics–based method to map B cell and T cell receptors.Targeted capture of antigen receptor sequences from spatial transcriptomics gene expression librari

Updated on: January 26,2024 17

New method is better able to map immune response and paves way for new treatments

byKarolinska InstitutetSpatial transcriptomics–based method to map B cell and T cell receptors.Targeted capture of antigen receptor sequences from spatial transcriptomics gene expression librari

Updated on:January 26,2024 17

CAR T cell therapy effective as first-line treatment for high-risk large B-cell lymphoma

by University of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainA study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-

Updated on: April 09,2024 15

CAR T cell therapy effective as first-line treatment for high-risk large B-cell lymphoma

by University of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainA study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-

Updated on:April 09,2024 15

An extra X chromosome-linked gene may explain decreased viral infection severity in females

by University of California, Los AngelesCredit: CC0 Public DomainIt has long been known that viral infections can be more severe in males than females, but the question as to why has remained a m

Updated on: April 24,2024 13

An extra X chromosome-linked gene may explain decreased viral infection severity in females

by University of California, Los AngelesCredit: CC0 Public DomainIt has long been known that viral infections can be more severe in males than females, but the question as to why has remained a m

Updated on:April 24,2024 13

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on: March 07,2024 12

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on:March 07,2024 12

Researchers develop statistical method for genetic mapping of autoimmune diseases

byBrigham and Women’s HospitalSchematic overview of SCENT and SCENT enhancer–gene pairs across nine single-cell multimodal datasets.a, SCENT identifies (1) activecis-regulatory regio

Updated on: April 27,2024 0

Researchers develop statistical method for genetic mapping of autoimmune diseases

byBrigham and Women’s HospitalSchematic overview of SCENT and SCENT enhancer–gene pairs across nine single-cell multimodal datasets.a, SCENT identifies (1) activecis-regulatory regio

Updated on:April 27,2024 0

Women who are 'larks' have a lower risk of developing breast cancer

by National Cancer Research InstituteThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by To

Updated on: March 13,2024 19

Women who are 'larks' have a lower risk of developing breast cancer

by National Cancer Research InstituteThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by To

Updated on:March 13,2024 19

Study links early TNF inhibitor treatment to higher heart disease risk in ankylosing spondylitis patients, with caveats

by American College of RheumatologyCredit: Jean Liew et al, The Association of Early TNF Inhibitor Use with Incident Cardiovascular Events in Ankylosing Spondylitis [abstract]. Arthritis Rheumato

Updated on: June 15,2024 7

Study links early TNF inhibitor treatment to higher heart disease risk in ankylosing spondylitis patients, with caveats

by American College of RheumatologyCredit: Jean Liew et al, The Association of Early TNF Inhibitor Use with Incident Cardiovascular Events in Ankylosing Spondylitis [abstract]. Arthritis Rheumato

Updated on:June 15,2024 7