Study reveals somatic mutation profile of colorectal tumor with simultaneous APC and MLH1 germline mutations

by Zhao Weiwei; Hong Bo, Hefei Institutes of Physical Science, Chinese Academy of SciencesThe pedigree of the studied family, and hematoxylin-eosin staining of colorectal adenocarcinoma or adenomas in

Updated on: February 20,2024 11

Study reveals somatic mutation profile of colorectal tumor with simultaneous APC and MLH1 germline mutations

by Zhao Weiwei; Hong Bo, Hefei Institutes of Physical Science, Chinese Academy of SciencesThe pedigree of the studied family, and hematoxylin-eosin staining of colorectal adenocarcinoma or adenomas in

Updated on:February 20,2024 11

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on: April 28,2024 0

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on:April 28,2024 0

Editorial: GBP3-STING interaction in glioblastoma coordinates poor response to temozolomide

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper was published inOncotarget, titled "GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative

Updated on: March 06,2024 13

Editorial: GBP3-STING interaction in glioblastoma coordinates poor response to temozolomide

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper was published inOncotarget, titled "GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative

Updated on:March 06,2024 13

Prediagnosis exercise may reduce CV risk in breast cancer

(HealthDay)—For women with primary breast cancer, prediagnosis exercise exposure is associated with a graded reduction in subsequent cardiovascular event (CVE) risk, according to a study published in

Updated on: April 14,2024 16

Prediagnosis exercise may reduce CV risk in breast cancer

(HealthDay)—For women with primary breast cancer, prediagnosis exercise exposure is associated with a graded reduction in subsequent cardiovascular event (CVE) risk, according to a study published in

Updated on:April 14,2024 16

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on: January 02,2024 8

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on:January 02,2024 8

Clinical trial generates promising results for immunotherapy drug nivolumab in patients with advanced skin cancer

byWileyCredit: CC0 Public DomainNumerous studies have shown that drugs called immune checkpoint inhibitors can boost the immune system's response against various cancers. Now a phase II clin

Updated on: January 02,2024 9

Clinical trial generates promising results for immunotherapy drug nivolumab in patients with advanced skin cancer

byWileyCredit: CC0 Public DomainNumerous studies have shown that drugs called immune checkpoint inhibitors can boost the immune system's response against various cancers. Now a phase II clin

Updated on:January 02,2024 9

Alterations in the blood immune system found to increase cancer risk

by Germans Trias i Pujol Research InstitutePleiotropicRNYsare linked to SLE risk and plasmaRNYsare relatively abundant preceding breast cancer diagnosis.aScatter pl

Updated on: April 22,2024 0

Alterations in the blood immune system found to increase cancer risk

by Germans Trias i Pujol Research InstitutePleiotropicRNYsare linked to SLE risk and plasmaRNYsare relatively abundant preceding breast cancer diagnosis.aScatter pl

Updated on:April 22,2024 0

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Updated on: March 30,2024 0

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Updated on:March 30,2024 0

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Updated on: January 02,2024 9

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Updated on:January 02,2024 9

Biomarkers show promise for identifying early risk of pancreatic cancer

byDuke University Medical CenterCredit: Pixabay/CC0 Public DomainA research team at Duke Health has identified a set of biomarkers that could help distinguish whether cysts on the pancreas are l

Updated on: January 04,2024 9

Biomarkers show promise for identifying early risk of pancreatic cancer

byDuke University Medical CenterCredit: Pixabay/CC0 Public DomainA research team at Duke Health has identified a set of biomarkers that could help distinguish whether cysts on the pancreas are l

Updated on:January 04,2024 9

Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

by The Spanish National Cancer Research CentreClinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm.AClinical trial treatment and s

Updated on: February 18,2024 17

Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

by The Spanish National Cancer Research CentreClinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm.AClinical trial treatment and s

Updated on:February 18,2024 17

New drug, WNTinib, delays tumor growth and improves survival in mouse models of children's liver cancer

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainA new drug called WNTinib can delay the growth of tumors and improve survival in hepatoblastoma, a type of

Updated on: November 08,2024 0

New drug, WNTinib, delays tumor growth and improves survival in mouse models of children's liver cancer

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainA new drug called WNTinib can delay the growth of tumors and improve survival in hepatoblastoma, a type of

Updated on:November 08,2024 0