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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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APC protein affects colon cancer immunity by preventing pre-cancerous inflammation

APC protein affects colon cancer immunity by preventing pre-cancerous inflammation

by Institut PasteurHuman T lymphocytes expressing or lacking APC. Lack of APC impairs microtubule cytoskeleton organization (green filaments). Credit: Institut PasteurAdenomatous polyposis coli (APC)

APC protein affects colon cancer immunity by preventing pre-cancerous inflammation

by Institut PasteurHuman T lymphocytes expressing or lacking APC. Lack of APC impairs microtubule cytoskeleton organization (green filaments). Credit: Institut PasteurAdenomatous polyposis coli (APC)
Editorial: GBP3-STING interaction in glioblastoma coordinates poor response to temozolomide

Editorial: GBP3-STING interaction in glioblastoma coordinates poor response to temozolomide

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper was published inOncotarget, titled "GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative

Editorial: GBP3-STING interaction in glioblastoma coordinates poor response to temozolomide

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper was published inOncotarget, titled "GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative
Study quantifies impact of NCI-sponsored trials on clinical cancer care

Study quantifies impact of NCI-sponsored trials on clinical cancer care

by National Cancer InstituteA study shows that 82 of 182 phase 3 clinical trials led by SWOG or by other NCTN groups with SWOG participation were 'practice influential'. Credit: National

Study quantifies impact of NCI-sponsored trials on clinical cancer care

by National Cancer InstituteA study shows that 82 of 182 phase 3 clinical trials led by SWOG or by other NCTN groups with SWOG participation were 'practice influential'. Credit: National
One simple change cut unnecessary imaging for cancer patients in half

One simple change cut unnecessary imaging for cancer patients in half

by Perelman School of Medicine at the University of PennsylvaniaKiller T cells surround a cancer cell. Credit: NIHSimply introducing a default physician order—a "nudge"—into electronic

One simple change cut unnecessary imaging for cancer patients in half

by Perelman School of Medicine at the University of PennsylvaniaKiller T cells surround a cancer cell. Credit: NIHSimply introducing a default physician order—a "nudge"—into electronic
Predicting oral cancer-related mortality among adults using machine learning approach

Predicting oral cancer-related mortality among adults using machine learning approach

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Unsplash/CC0 Public DomainA study aiming to predict oral cancer-related mortality among adults in the United States and

Predicting oral cancer-related mortality among adults using machine learning approach

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Unsplash/CC0 Public DomainA study aiming to predict oral cancer-related mortality among adults in the United States and
Team targets tumor suppressor to treat 'triple-negative' breast cancer

Team targets tumor suppressor to treat 'triple-negative' breast cancer

by University of Arizona Health SciencesAgnieszka Witkiewicz, MD and Erik Knudsen, PhD, UA Cancer Center. Credit: BioCommunications, Kris HanningA study by scientists at the University of Arizona Canc

Team targets tumor suppressor to treat 'triple-negative' breast cancer

by University of Arizona Health SciencesAgnieszka Witkiewicz, MD and Erik Knudsen, PhD, UA Cancer Center. Credit: BioCommunications, Kris HanningA study by scientists at the University of Arizona Canc
Boosting T cell 'memory' may result in longer-lasting and effective responses for patients

Boosting T cell 'memory' may result in longer-lasting and effective responses for patients

by University of Texas M. D. Anderson Cancer CenterScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDJust like pe

Boosting T cell 'memory' may result in longer-lasting and effective responses for patients

by University of Texas M. D. Anderson Cancer CenterScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDJust like pe
Metalloimmunotherapy: Combination of cisplatin and STING agonist into one molecule boosts cancer immune response

Metalloimmunotherapy: Combination of cisplatin and STING agonist into one molecule boosts cancer immune response

by Science China PressSchematic illustration of the construction of conjugates I and II. Schematic illustration of the combinational effects on tumors of the PtIV-MSA-2 conjugates. The PtIV-MSA-2

Metalloimmunotherapy: Combination of cisplatin and STING agonist into one molecule boosts cancer immune response

by Science China PressSchematic illustration of the construction of conjugates I and II. Schematic illustration of the combinational effects on tumors of the PtIV-MSA-2 conjugates. The PtIV-MSA-2
Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti
Researchers are building detailed maps of colorectal cancer to better understand the dynamics of the disease

Researchers are building detailed maps of colorectal cancer to better understand the dynamics of the disease

by Harvard Medical SchoolA 3D reconstruction of colorectal cancer revealed that what was once thought to be 2D mucin pools with clusters of cancer cells floating inside is actually a complex and

Researchers are building detailed maps of colorectal cancer to better understand the dynamics of the disease

by Harvard Medical SchoolA 3D reconstruction of colorectal cancer revealed that what was once thought to be 2D mucin pools with clusters of cancer cells floating inside is actually a complex and
Social vulnerability tied to worse pediatric head and neck cancer outcomes

Social vulnerability tied to worse pediatric head and neck cancer outcomes

by Lori SolomonAmong pediatric patients with head and neck cancers (HNCs), increasing social vulnerability is associated with significant decreases in receipt of care and survival time, according to a

Social vulnerability tied to worse pediatric head and neck cancer outcomes

by Lori SolomonAmong pediatric patients with head and neck cancers (HNCs), increasing social vulnerability is associated with significant decreases in receipt of care and survival time, according to a
Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

by The Spanish National Cancer Research CentreClinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm.AClinical trial treatment and s

Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

by The Spanish National Cancer Research CentreClinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm.AClinical trial treatment and s