Sunitinib Elicits Improved Efficacy Vs Placebo in Malignant Pheochromocytoma/Paragangliomas

September 20, 2021Kristie L. KahlFirst-line sunitinib was found to improve efficacy compared with placebo in patients with malignant pheochromocytoma and paragangliomas.First-line sunitinib (Sut

Updated on: October 24,2023 32

Sunitinib Elicits Improved Efficacy Vs Placebo in Malignant Pheochromocytoma/Paragangliomas

September 20, 2021Kristie L. KahlFirst-line sunitinib was found to improve efficacy compared with placebo in patients with malignant pheochromocytoma and paragangliomas.First-line sunitinib (Sut

Updated on:October 24,2023 32

First immunotherapy success for triple-negative breast cancer

byQueen Mary, University of LondonThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by

Updated on: December 18,2023 23

First immunotherapy success for triple-negative breast cancer

byQueen Mary, University of LondonThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by

Updated on:December 18,2023 23

Ultrasound-guided surgery could be quicker, less painful and more effective for treating early form of breast cancer

by European Organisation for Research and Treatment of CancerAntonio Esgueva using IOUS to guide breast surgery. Credit: Antonio Esguega / EORTCUsing ultrasound to guide surgery for patients with duct

Updated on: December 19,2023 15

Ultrasound-guided surgery could be quicker, less painful and more effective for treating early form of breast cancer

by European Organisation for Research and Treatment of CancerAntonio Esgueva using IOUS to guide breast surgery. Credit: Antonio Esguega / EORTCUsing ultrasound to guide surgery for patients with duct

Updated on:December 19,2023 15

Targeted therapy momelotinib provides significant symptom and anemia improvements in patients with myelofibrosis

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainPatients with myelofibrosis had clinically significant improvement in disease-related symptoms, including anem

Updated on: December 19,2023 10

Targeted therapy momelotinib provides significant symptom and anemia improvements in patients with myelofibrosis

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainPatients with myelofibrosis had clinically significant improvement in disease-related symptoms, including anem

Updated on:December 19,2023 10

Adding immunotherapy to chemotherapy regimen improves survival in metastatic bladder cancer patients

byThe Mount Sinai HospitalCredit: Unsplash/CC0 Public DomainA clinical trial co-led by Mount Sinai researchers is the first to show that using chemotherapy with immunotherapy resulted in improve

Updated on: October 23,2023 164

Adding immunotherapy to chemotherapy regimen improves survival in metastatic bladder cancer patients

byThe Mount Sinai HospitalCredit: Unsplash/CC0 Public DomainA clinical trial co-led by Mount Sinai researchers is the first to show that using chemotherapy with immunotherapy resulted in improve

Updated on:October 23,2023 164

Fertility preservation measures do not appear to increase the risk of breast cancer recurrence

byKarolinska InstitutetCancer-Specific Survival in the Cohort. FP indicates fertility preservation. Credit:JAMA OncologyDOI: 10.1001/jamaoncol.2022.3677Women with a breast cancer dia

Updated on: December 19,2023 9

Fertility preservation measures do not appear to increase the risk of breast cancer recurrence

byKarolinska InstitutetCancer-Specific Survival in the Cohort. FP indicates fertility preservation. Credit:JAMA OncologyDOI: 10.1001/jamaoncol.2022.3677Women with a breast cancer dia

Updated on:December 19,2023 9

The phenotypic plasticity effect of cancer cells and how to exploit it

by Michael Hesse,Max Planck SocietyMathematical model of tumor heterogeneity and phenotype switching: A detailed analysis. Credit: M.Raatz, MPI for Evolutionary BiologyCancer cells are notorious

Updated on: October 31,2023 20

The phenotypic plasticity effect of cancer cells and how to exploit it

by Michael Hesse,Max Planck SocietyMathematical model of tumor heterogeneity and phenotype switching: A detailed analysis. Credit: M.Raatz, MPI for Evolutionary BiologyCancer cells are notorious

Updated on:October 31,2023 20

Researchers identify molecular characteristics of leptomeningeal melanoma metastases

byH. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Patients w

Updated on: December 20,2023 19

Researchers identify molecular characteristics of leptomeningeal melanoma metastases

byH. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Patients w

Updated on:December 20,2023 19

α-KG-dependent glycolysis activation by BCAT1 contributes to EGFR-TKI resistance in NSCLC

Updated on: November 28,2024 0

α-KG-dependent glycolysis activation by BCAT1 contributes to EGFR-TKI resistance in NSCLC

Updated on:November 28,2024 0

New near-infrared activated photo-oxidants kill cancer cells without oxygen

A research team led by scientists from City University of Hong Kong (CityU) has achieved a significant breakthrough by inventing a new class of near-infrared-activated photo-oxidants that can effectiv

Updated on: November 12,2023 21

New near-infrared activated photo-oxidants kill cancer cells without oxygen

A research team led by scientists from City University of Hong Kong (CityU) has achieved a significant breakthrough by inventing a new class of near-infrared-activated photo-oxidants that can effectiv

Updated on:November 12,2023 21

UC San Diego Moores administers its first personalized cancer vaccine

by Paul Sisson, The San Diego Union-TribuneCredit: Min Yu (Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC),USC Norris Comprehensive Cancer CenterMore than 18 round

Updated on: December 18,2023 18

UC San Diego Moores administers its first personalized cancer vaccine

by Paul Sisson, The San Diego Union-TribuneCredit: Min Yu (Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC),USC Norris Comprehensive Cancer CenterMore than 18 round

Updated on:December 18,2023 18

Novel therapeutic targets discovered for triple-negative breast cancer

by Melissa Rohman,Northwestern UniversityThe signature of TRIM21low/CD73highis associated with unfavorable immune response. (A) Proteomic data from CPTAC identified that the expression of

Updated on: December 21,2023 13

Novel therapeutic targets discovered for triple-negative breast cancer

by Melissa Rohman,Northwestern UniversityThe signature of TRIM21low/CD73highis associated with unfavorable immune response. (A) Proteomic data from CPTAC identified that the expression of

Updated on:December 21,2023 13