Targeting epiregulin in treatment-damaged tumor microenvironment restrains therapeutic resistance

by Liu Jia,Chinese Academy of SciencesGenotoxicity induces expression of EREG and other secreted factors of the SASP spectrum in human stromal cells.aTranscriptome-wide profiling of

Updated on: December 19,2023

Targeting epiregulin in treatment-damaged tumor microenvironment restrains therapeutic resistance

by Liu Jia,Chinese Academy of SciencesGenotoxicity induces expression of EREG and other secreted factors of the SASP spectrum in human stromal cells.aTranscriptome-wide profiling of

Updated on:December 19,2023

Druggable targets found for treating rare, deadly nerve cancer MPNST

byCincinnati Children's Hospital Medical CenterTumor cell–state trajectories from NF to MPNST inferred by Slingshot. Arrows, transformation direction. Credit: Cincinnati Children's and S

Updated on: December 22,2023

Druggable targets found for treating rare, deadly nerve cancer MPNST

byCincinnati Children's Hospital Medical CenterTumor cell–state trajectories from NF to MPNST inferred by Slingshot. Arrows, transformation direction. Credit: Cincinnati Children's and S

Updated on:December 22,2023

Scientists develop new ultrasound technique for earlier detection and diagnosis of breast cancer

byNational Physical LaboratoryCredit: Unsplash/CC0 Public DomainScientists at the UK's National Physical Laboratory (NPL) have demonstrated the first in-person measurements of breast tissue

Updated on: December 27,2023

Scientists develop new ultrasound technique for earlier detection and diagnosis of breast cancer

byNational Physical LaboratoryCredit: Unsplash/CC0 Public DomainScientists at the UK's National Physical Laboratory (NPL) have demonstrated the first in-person measurements of breast tissue

Updated on:December 27,2023

Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

byUniversity of BarcelonaGenetic models to mimic SMAD2/3 alterations in patient-derived ADC-TAFs and SCC-TAFs. a–c, Fold SMAD3 (a) and SMAD2 (b) mRNA and corresponding ratio (c) in primary lung

Updated on: December 21,2023

Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

byUniversity of BarcelonaGenetic models to mimic SMAD2/3 alterations in patient-derived ADC-TAFs and SCC-TAFs. a–c, Fold SMAD3 (a) and SMAD2 (b) mRNA and corresponding ratio (c) in primary lung

Updated on:December 21,2023

Dementia complicates cancer care, increasing risk of poorer clinical outcome and patient experience

byRegenstrief InstituteCredit: Pixabay/CC0 Public DomainPre-existing dementia complicates cancer care and increases the risk of worse clinical outcomes and inferior patient experience, according

Updated on: December 19,2023

Dementia complicates cancer care, increasing risk of poorer clinical outcome and patient experience

byRegenstrief InstituteCredit: Pixabay/CC0 Public DomainPre-existing dementia complicates cancer care and increases the risk of worse clinical outcomes and inferior patient experience, according

Updated on:December 19,2023

Symptom self-monitoring for childhood cancer survivors—what are oncologists' views?

byKing's College LondonCredit: Unsplash/CC0 Public DomainA new international survey, led by the Stanford University Department of Anesthesiology, Perioperative, and Pain Medicine, and the In

Updated on: December 21,2023

Symptom self-monitoring for childhood cancer survivors—what are oncologists' views?

byKing's College LondonCredit: Unsplash/CC0 Public DomainA new international survey, led by the Stanford University Department of Anesthesiology, Perioperative, and Pain Medicine, and the In

Updated on:December 21,2023

Hormone resistance in breast cancer linked to DNA 'rewiring'

byGarvan Institute of Medical ResearchCredit: CC0 Public DomainEpigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatm

Updated on: December 20,2023

Hormone resistance in breast cancer linked to DNA 'rewiring'

byGarvan Institute of Medical ResearchCredit: CC0 Public DomainEpigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatm

Updated on:December 20,2023

Estrogen Receptor Mutation Prospects in Endometrial Cancer Treatment

byHemalatha Manikandanon August 22, 2023Inhibiting CDK9, a protein that works withestrogen receptors, was effective at minimizing the proliferation ofendometrial cancerce

Updated on: December 19,2023

Estrogen Receptor Mutation Prospects in Endometrial Cancer Treatment

byHemalatha Manikandanon August 22, 2023Inhibiting CDK9, a protein that works withestrogen receptors, was effective at minimizing the proliferation ofendometrial cancerce

Updated on:December 19,2023

New insights into the drivers of glioma-related epilepsy

by Graciela Gutierrez,Baylor College of MedicineGraphical abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.01.013Glioma is one of the most aggressive malignant primary brain

Updated on: December 20,2023

New insights into the drivers of glioma-related epilepsy

by Graciela Gutierrez,Baylor College of MedicineGraphical abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.01.013Glioma is one of the most aggressive malignant primary brain

Updated on:December 20,2023

Results mixed for twice-daily APBI in early breast cancer

(HealthDay)—Accelerated partial breast irradiation (APBI) delivered twice per day over one week to the tumor bed is noninferior to whole breast irradiation for preventing ipsilateral breast tumor recu

Updated on: December 22,2023

Results mixed for twice-daily APBI in early breast cancer

(HealthDay)—Accelerated partial breast irradiation (APBI) delivered twice per day over one week to the tumor bed is noninferior to whole breast irradiation for preventing ipsilateral breast tumor recu

Updated on:December 22,2023

MicroRNA is the master regulator of the genome—researchers are learning how to harness the way it controls genes

by Andrea Kasinski,The ConversationMicroRNA can silence genes by binding to mRNA. Credit:Kajsa Mollersen/Wikimedia Commons,CC BY-SAThe Earthformed 4.5 billion years ago, and li

Updated on: December 20,2023

MicroRNA is the master regulator of the genome—researchers are learning how to harness the way it controls genes

by Andrea Kasinski,The ConversationMicroRNA can silence genes by binding to mRNA. Credit:Kajsa Mollersen/Wikimedia Commons,CC BY-SAThe Earthformed 4.5 billion years ago, and li

Updated on:December 20,2023

Researchers identify new genetic risk factors for persistent HPV infections

byUniversity of Maryland School of MedicineDistribution of binding affinity IC50 values by HLA-DRB1 allele category (A) all binding predictions (B) Excluding non-binders (lC50 > 5000 nM). Cre

Updated on: April 27,2024

Researchers identify new genetic risk factors for persistent HPV infections

byUniversity of Maryland School of MedicineDistribution of binding affinity IC50 values by HLA-DRB1 allele category (A) all binding predictions (B) Excluding non-binders (lC50 > 5000 nM). Cre

Updated on:April 27,2024