Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi

Updated on: January 17,2025

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi

Updated on:January 17,2025

Reducing dose of popular blood thinners may limit risk of future bleeding, study finds

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainFor people taking popular blood thinners after having a blood clot, a reduced dose may limit the future risk of bleeding as well as hospi

Updated on: January 17,2025

Reducing dose of popular blood thinners may limit risk of future bleeding, study finds

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainFor people taking popular blood thinners after having a blood clot, a reduced dose may limit the future risk of bleeding as well as hospi

Updated on:January 17,2025

Innovative red blood cell shape test promises better blood storage and transfusions

Innovative red blood cell shape test promises better blood storage and transfusionsbyUniversity of OxfordCredit: Pixabay/CC0 Public DomainScientists have developed a way of assessing the ability

Updated on: January 06,2025

Innovative red blood cell shape test promises better blood storage and transfusions

Innovative red blood cell shape test promises better blood storage and transfusionsbyUniversity of OxfordCredit: Pixabay/CC0 Public DomainScientists have developed a way of assessing the ability

Updated on:January 06,2025

Auto hematopoietic cell transplant not beneficial for mantle cell lymphoma with undetectable residual disease

by Elana GotkineAutologous hematopoietic cell transplant (auto-HCT) is not beneficial for patients with mantle cell lymphoma (MCL) in first complete remission (CR) with undetectable minimal residual d

Updated on: December 21,2024

Auto hematopoietic cell transplant not beneficial for mantle cell lymphoma with undetectable residual disease

by Elana GotkineAutologous hematopoietic cell transplant (auto-HCT) is not beneficial for patients with mantle cell lymphoma (MCL) in first complete remission (CR) with undetectable minimal residual d

Updated on:December 21,2024

Scientists expose cells driving aggressive tumor growth

byUniversity College LondonSPRINTER identifies tumor clone proliferation heterogeneity in patient CRUKP9145 with NSCLC. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01989-zT

Updated on: December 21,2024

Scientists expose cells driving aggressive tumor growth

byUniversity College LondonSPRINTER identifies tumor clone proliferation heterogeneity in patient CRUKP9145 with NSCLC. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01989-zT

Updated on:December 21,2024

Annual report reveals more cancers are being treated with personalized therapies before surgery

byAmerican College of SurgeonsWhat to know about breast cancer according to the National Cancer Database. Credit: American College of SurgeonsBreast, bladder, and pancreatic cancers are increasi

Updated on: December 21,2024

Annual report reveals more cancers are being treated with personalized therapies before surgery

byAmerican College of SurgeonsWhat to know about breast cancer according to the National Cancer Database. Credit: American College of SurgeonsBreast, bladder, and pancreatic cancers are increasi

Updated on:December 21,2024

Immunosuppression study helps understand why some prostate cancer treatments do not work as expected

byTampere UniversityOn the left is a tissue sample from the prostate stained with hematoxylin and eosin. Hematoxylin stains the nuclei blue or purple because it binds to DNA, and eosin stains th

Updated on: December 21,2024

Immunosuppression study helps understand why some prostate cancer treatments do not work as expected

byTampere UniversityOn the left is a tissue sample from the prostate stained with hematoxylin and eosin. Hematoxylin stains the nuclei blue or purple because it binds to DNA, and eosin stains th

Updated on:December 21,2024

Anticancer drugs could make immunotherapies more effective

byWeill Cornell Medical CollegePretreatment with EZH2 inhibitor (top right) leads to higher recruitment of CAR-T cells (red) into the lymph node tumor compared with control (top left). Pretreatm

Updated on: December 21,2024

Anticancer drugs could make immunotherapies more effective

byWeill Cornell Medical CollegePretreatment with EZH2 inhibitor (top right) leads to higher recruitment of CAR-T cells (red) into the lymph node tumor compared with control (top left). Pretreatm

Updated on:December 21,2024

Changes in blood cell production over the lifetime could impact leukemia outcomes

by Susanne Clara Bard,University of California - San DiegoCredit: Unsplash/CC0 Public DomainResearchers at University of California San Diego School of Medicine and their colleagues have develop

Updated on: December 21,2024

Changes in blood cell production over the lifetime could impact leukemia outcomes

by Susanne Clara Bard,University of California - San DiegoCredit: Unsplash/CC0 Public DomainResearchers at University of California San Diego School of Medicine and their colleagues have develop

Updated on:December 21,2024

Research reveals how fructose in diet enhances tumor growth

byWashington University in St. LouisCredit: CC0 Public DomainFructose consumption has increased considerably over the past five decades, largely due to the widespread use of high-fructose corn s

Updated on: December 21,2024

Research reveals how fructose in diet enhances tumor growth

byWashington University in St. LouisCredit: CC0 Public DomainFructose consumption has increased considerably over the past five decades, largely due to the widespread use of high-fructose corn s

Updated on:December 21,2024

Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

byUniversity of TokyoCancer cell during cell division. Credit: National Institutes of HealthTreatment for more advanced and difficult-to-treat head and neck cancers can be improved with the addi

Updated on: December 21,2024

Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

byUniversity of TokyoCancer cell during cell division. Credit: National Institutes of HealthTreatment for more advanced and difficult-to-treat head and neck cancers can be improved with the addi

Updated on:December 21,2024

Computational model for drug resistance assessment can improve treatment for leukemia and lung cancer

byLinnaeus UniversityCredit: Unsplash/CC0 Public DomainA new method can improve treatment for patients with chronic myeloid leukemia by predicting which medication will be most effective. The me

Updated on: December 21,2024

Computational model for drug resistance assessment can improve treatment for leukemia and lung cancer

byLinnaeus UniversityCredit: Unsplash/CC0 Public DomainA new method can improve treatment for patients with chronic myeloid leukemia by predicting which medication will be most effective. The me

Updated on:December 21,2024